Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

Rac1 Regulates Myosin II Phosphorylation Through Regulation of Myosin Light Chain Phosphatase

(2015) Keita Shibata et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Flightless I interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling

(2015) Pamma D. Arora et al.   MOLECULAR BIOLOGY OF THE CELL

Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells

(2014) Alexander Braun et al.   JOURNAL OF CELL BIOLOGY

Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure

(2014) R. C. Williamson et al.   JOURNAL OF CELL SCIENCE

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer

(2013) M. Nobis et al.   CANCER RESEARCH

P-Rex1 Cooperates with PDGFRβ to Drive Cellular Migration in 3D Microenvironments

(2013) Andrew D. Campbell et al.   PLoS One

Flightless I is a focal adhesion-associated actin-capping protein that regulates cell migration

(2012) Ibrahim Mohammad et al.   FASEB JOURNAL

Functional specialisation of yeast Rho1 GTP exchange factors

(2012) S. A. Krause et al.   JOURNAL OF CELL SCIENCE

Mtss1 Promotes Cell-Cell Junction Assembly and Stability through the Small GTPase Rac1

(2012) John C. Dawson et al.   PLoS One

The diverse roles of Rac signaling in tumorigenesis

(2011) Natalie A. Mack et al.   CELL CYCLE

Ajuba is required for Rac activation and maintenance of E-cadherin adhesion

(2011) Sébastien Nola et al.   JOURNAL OF CELL BIOLOGY

Regulation of Focal Adhesions by Flightless I Involves Inhibition of Paxillin Phosphorylation via a Rac1-Dependent Pathway

(2011) Zlatko Kopecki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Decreased expression of Flightless I, a gelsolin family member and developmental regulator, in early-gestation fetal wounds improves healing

(2011) Cheng-Hung Lin et al.   MAMMALIAN GENOME

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

(2011) Colin R. Lindsay et al.   Nature Communications

Rac and Rho GTPases in cancer cell motility control

(2010) Matteo Parri et al.   Cell Communication and Signaling

Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COSphox cells

(2010) Baoming Nie et al.   CELLULAR SIGNALLING

Scaffold Proteins IRSp53 and Spinophilin Regulate Localized Rac Activation by T-lymphocyte Invasion and Metastasis Protein 1 (TIAM1)

(2010) Soumitra Rajagopal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Motility in Metastasizing Cells

(2010) Mahmut Yilmaz et al.   MOLECULAR CANCER RESEARCH

NetPath: a public resource of curated signal transduction pathways

(2010) Kumaran Kandasamy et al.   GENOME BIOLOGY

Scoring of collagen organization in healthy and diseased human dermis by multiphoton microscopy

(2009) Riccardo Cicchi et al.   Journal of Biophotonics

Flightless I Regulates Hemidesmosome Formation and Integrin-Mediated Cellular Adhesion and Migration during Wound Repair

(2009) Zlatko Kopecki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

(2009) J Qin et al.   ONCOGENE

Arp2/3 complex activity in filopodia of spreading cells

(2008) Simon A Johnston et al.   BMC CELL BIOLOGY

PIPs: human protein-protein interaction prediction database

(2008) M. D. McDowall et al.   NUCLEIC ACIDS RESEARCH

Gender specific effects on the actin-remodelling protein Flightless I and TGF-β1 contribute to impaired wound healing in aged skin

(2007) Damian H. Adams et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY