Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4
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Title
Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4
Authors
Keywords
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Journal
Nature Communications
Volume 7, Issue -, Pages 10857
Publisher
Springer Nature
Online
2016-03-03
DOI
10.1038/ncomms10857
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Note: Only part of the references are listed.- TH9 cells are required for tissue mast cell accumulation during allergic inflammation
- (2015) Sarita Sehra et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell–Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9–Producing T Cells
- (2015) Arianne C. Richard et al. JOURNAL OF IMMUNOLOGY
- Peripheral blood Th9 cells and eosinophil apoptosis in asthma patients
- (2015) Deimantė Hoppenot et al. Medicina-Lithuania
- Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response
- (2015) Yonglian Sun et al. Science Signaling
- T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens
- (2015) Guillaume Voisinne et al. Cell Reports
- Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response
- (2015) Yonglian Sun et al. Science Signaling
- Peripheral blood Th9 cells and eosinophil apoptosis in asthma patients
- (2015) Deimantė Hoppenot et al. Medicina-Lithuania
- IRF4 at the crossroads of effector T-cell fate decision
- (2014) Magdalena Huber et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation
- (2014) Timotheus Y.F. Halim et al. IMMUNITY
- MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion
- (2014) Christopher J. Oliphant et al. IMMUNITY
- Complex interactions of transcription factors in mediating cytokine biology in T cells
- (2014) Peng Li et al. IMMUNOLOGICAL REVIEWS
- Counter-regulation of T cell effector function by differentially activated p38
- (2014) Muhammad S. Alam et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells
- (2014) Julio Gomez-Rodriguez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Naive and Innate Memory Phenotype CD4+ T Cells Have Different Requirements for Active Itk for Their Development
- (2014) J. Hu et al. JOURNAL OF IMMUNOLOGY
- BCL6 Controls Th9 Cell Development by Repressing Il9 Transcription
- (2014) R. Bassil et al. JOURNAL OF IMMUNOLOGY
- The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation
- (2014) Weishan Huang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression
- (2014) Wei Liao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phenotype and functions of memory Tfh cells in human blood
- (2014) Nathalie Schmitt et al. TRENDS IN IMMUNOLOGY
- Nitric oxide enhances Th9 cell differentiation and airway inflammation
- (2014) Wanda Niedbala et al. Nature Communications
- Interferon Regulatory Factor 4 Sustains CD8+ T Cell Expansion and Effector Differentiation
- (2013) Shuyu Yao et al. IMMUNITY
- Interleukin-9 Is Required for Allergic Airway Inflammation Mediated by the Cytokine TSLP
- (2013) Weiguo Yao et al. IMMUNITY
- Early signaling events that underlie fate decisions of naive CD4+T cells toward distinct T-helper cell subsets
- (2013) Hidehiro Yamane et al. IMMUNOLOGICAL REVIEWS
- Orai1-NFAT signalling pathway triggered by T cell receptor stimulation
- (2013) Sonal Srikanth et al. MOLECULES AND CELLS
- The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells
- (2013) Kevin Man et al. NATURE IMMUNOLOGY
- IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation
- (2012) Clare S. Hardman et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Activin A and TGF-β promote TH9 cell–mediated pulmonary allergic pathology
- (2012) Carla P. Jones et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Nuclear Factor of Activated T Cells 1 (NFAT1)-induced Permissive Chromatin Modification Facilitates Nuclear Factor-κB (NF-κB)-mediated Interleukin-9 (IL-9) Transactivation
- (2012) Arijita Jash et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- OX40 signaling favors the induction of TH9 cells and airway inflammation
- (2012) Xiang Xiao et al. NATURE IMMUNOLOGY
- TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation
- (2012) R. Nayar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Association of a Single-Nucleotide Polymorphism of the IL-2 Inducible T-cell Kinase Gene with Asthma
- (2011) Shin-Hwa Lee et al. ANNALS OF HUMAN GENETICS
- Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates
- (2011) Julio Gomez-Rodriguez et al. FEBS Journal
- STAT6-Dependent Regulation of Th9 Development
- (2011) R. Goswami et al. JOURNAL OF IMMUNOLOGY
- An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
- (2011) Christoph Wilhelm et al. NATURE IMMUNOLOGY
- IL-9 Governs Allergen-induced Mast Cell Numbers in the Lung and Chronic Remodeling of the Airways
- (2010) Jennifer Kearley et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells
- (2010) Valérie Staudt et al. IMMUNITY
- Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response
- (2010) Ofer Feinerman et al. Molecular Systems Biology
- The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
- (2010) Hua-Chen Chang et al. NATURE IMMUNOLOGY
- The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
- (2009) Di Yu et al. IMMUNITY
- Differential Expression of Interleukin-17A and -17F Is Coupled to T Cell Receptor Signaling via Inducible T Cell Kinase
- (2009) Julio Gomez-Rodriguez et al. IMMUNITY
- IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity
- (2008) Elizabeth E. Forbes et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset
- (2008) Marc Veldhoen et al. NATURE IMMUNOLOGY
- IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells
- (2008) Valérie Dardalhon et al. NATURE IMMUNOLOGY
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