MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

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Human DNA Exonuclease TREX1 Is Also an Exoribonuclease That Acts on Single-stranded RNA

(2015) Fenghua Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

(2015) Jessica L. Grieves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The glioblastoma vasculature as a target for cancer therapy: Figure 1

(2014) Anna Dimberg   BIOCHEMICAL SOCIETY TRANSACTIONS

Sequencing of Antiangiogenic Agents in the Treatment of Metastatic Colorectal Cancer

(2014) James J. Lee et al.   Clinical Colorectal Cancer

The 3′–5′ DNA Exonuclease TREX1 Directly Interacts with Poly(ADP-ribose) Polymerase-1 (PARP1) during the DNA Damage Response

(2014) Takuya Miyazaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

(2014) James E. Dahlman et al.   Nature Nanotechnology

Small RNA combination therapy for lung cancer

(2014) W. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis

(2013) Zhen Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

The Exonuclease Trex1 Restrains Macrophage Proinflammatory Activation

(2013) S. Pereira-Lopes et al.   JOURNAL OF IMMUNOLOGY

Deregulated Type I IFN Response in TREX1-Associated Familial Chilblain Lupus

(2013) Katrin Peschke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Systematic Screen Identifies miRNAs That Target RAD51 and RAD51D to Enhance Chemosensitivity

(2013) J.-W. Huang et al.   MOLECULAR CANCER RESEARCH

miRNAs as Modulators of Angiogenesis

(2013) S. Landskroner-Eiger et al.   Cold Spring Harbor Perspectives in Medicine

The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies

(2012) Emmanouil Fokas et al.   CANCER AND METASTASIS REVIEWS

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Pathological neoangiogenesis depends on oxidative stress regulation by ATM

(2012) Yuji Okuno et al.   NATURE MEDICINE

Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach

(2012) X. A. Cambronne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential macrophage programming in the tumor microenvironment

(2012) Brian Ruffell et al.   TRENDS IN IMMUNOLOGY

A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor

(2011) Sophie Chabot et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers

(2011) Michela Garofalo et al.   NATURE MEDICINE

A MicroRNA Targeting Dicer for Metastasis Control

(2010) Graziano Martello et al.   CELL

New roles for the major human 3′-5′ exonuclease TREX1 in human disease

(2010) David Kavanagh et al.   CELL CYCLE

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

(2010) Nan Yan et al.   NATURE IMMUNOLOGY

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

IP-10 induces dissociation of newly formed blood vessels

(2009) R. J. Bodnar et al.   JOURNAL OF CELL SCIENCE

Histone H2AX is integral to hypoxia-driven neovascularization

(2009) Matina Economopoulou et al.   NATURE MEDICINE

miRNA in situ hybridization in formaldehyde and EDC–fixed tissues

(2009) John T G Pena et al.   NATURE METHODS

Targeting angiogenesis: progress with anti-VEGF treatment with large molecules

(2009) Axel Grothey et al.   Nature Reviews Clinical Oncology