Diverse chemotypes disrupt ion homeostasis in the malaria parasite

Plasma Membrane Calcium ATPases as Novel Candidates for Therapeutic Agent Development

(2016) Emanuel E Strehler   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Spiroindolone KAE609 for Falciparum and Vivax Malaria

(2014) Nicholas J. White et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiapicoplast and Gametocytocidal Screening To Identify the Mechanisms of Action of Compounds within the Malaria Box

(2013) Jessica D. Bowman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay

(2013) Leonardo Lucantoni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

(2013) Natalie J. Spillman et al.   Cell Host & Microbe

Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance

(2013) C. Wongsrichanalai et al.   CLINICAL MICROBIOLOGY AND INFECTION

Identification of inhibitors of Plasmodium falciparum gametocyte development

(2013) Sandra Duffy et al.   MALARIA JOURNAL

Na+ extrusion imposes an acid load on the intraerythrocytic malaria parasite

(2013) Natalie J. Spillman et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Malaria parasites tolerate a broad range of ionic environments and do not require host cation remodelling

(2013) Ajay D. Pillai et al.   MOLECULAR MICROBIOLOGY

Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated

(2013) Christina Spry et al.   PLoS One

The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases

(2013) Thomas Spangenberg et al.   PLoS One

The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector

(2012) J. C. van Pelt-Koops et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

X-Ray Microanalysis Investigation of the Changes in Na, K, and Hemoglobin Concentration in Plasmodium falciparum-Infected Red Blood Cells

(2011) Jakob M.A. Mauritz et al.   BIOPHYSICAL JOURNAL

The Phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii Reveal Unusual Adaptations Within and Beyond the Parasites' Boundaries

(2011) Moritz Treeck et al.   Cell Host & Microbe

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Chemical genetics of Plasmodium falciparum

(2010) W. Armand Guiguemde et al.   NATURE

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Plasmodium falciparum culture: The benefits of shaking

(2009) Richard J.W. Allen et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The Inhibitory Effect of 2-Halo Derivatives of D-Glucose on Glycolysis and on the Proliferation of the Human Malaria Parasite Plasmodium falciparum

(2008) D. A. van Schalkwyk et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

In silicoactivity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

(2008) David Plouffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA