Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways

WNT-SHH Antagonism Specifies and Expands Stem Cells prior to Niche Formation

(2016) Tamara Ouspenskaia et al.   CELL

Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer

(2016) P. S. Mathur et al.   MOLECULAR CANCER RESEARCH

Opposing Activities of Notch and Wnt Signaling Regulate Intestinal Stem Cells and Gut Homeostasis

(2015) Hua Tian et al.   Cell Reports

Roles for Hedgehog signaling in adult organ homeostasis and repair

(2014) R. Petrova et al.   DEVELOPMENT

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

YAP and TAZ, Hippo Signaling Targets, Act as a Rheostat for Nuclear SHP2 Function

(2013) Ryouhei Tsutsumi et al.   DEVELOPMENTAL CELL

WNT10B/β-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer

(2013) Peter Wend et al.   EMBO Molecular Medicine

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Notch Signaling Is Activated in Human Hepatocellular Carcinoma and Induces Tumor Formation in Mice

(2012) Augusto Villanueva et al.   GASTROENTEROLOGY

Morphogen Gradients: From Generation to Interpretation

(2011) Katherine W. Rogers et al.   Annual Review of Cell and Developmental Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

SHP2 Tyrosine Phosphatase Converts Parafibromin/Cdc73 from a Tumor Suppressor to an Oncogenic Driver

(2011) Atsushi Takahashi et al.   MOLECULAR CELL

Sonic Hedgehog Acts as a Negative Regulator of β-Catenin Signaling in the Adult Tongue Epithelium

(2010) Fabian T. Schneider et al.   AMERICAN JOURNAL OF PATHOLOGY

The Arabidopsis Paf1c Complex Component CDC73 Participates in the Modification of FLOWERING LOCUS C Chromatin

(2010) X. Yu et al.   PLANT PHYSIOLOGY

HMGA1 Is Induced by Wnt/β-Catenin Pathway and Maintains Cell Proliferation in Gastric Cancer

(2009) Shin-ichi Akaboshi et al.   AMERICAN JOURNAL OF PATHOLOGY

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Depletion of the Colonic Epithelial Precursor Cell Compartment Upon Conditional Activation of the Hedgehog Pathway

(2009) Willemijn A. van Dop et al.   GASTROENTEROLOGY

GLI1 Is a Direct Transcriptional Target of EWS-FLI1 Oncoprotein

(2009) Elspeth Beauchamp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parafibromin - functional insights

(2009) P. J. Newey et al.   JOURNAL OF INTERNAL MEDICINE

The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control

(2009) Christian Mosimann et al.   MECHANISMS OF DEVELOPMENT

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

(2009) S. Fre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Organ Growth by Morphogen Gradients

(2009) G. Schwank et al.   Cold Spring Harbor Perspectives in Biology

Crosstalk of hedgehog and Wnt pathways in gastric cancer

(2008) Kosuke Yanai et al.   CANCER LETTERS

Parafibromin, a Component of the Human PAF Complex, Regulates Growth Factors and Is Required for Embryonic Development and Survival in Adult Mice

(2008) P. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY