Bcl-2 proteins bid and bax form a network to permeabilize the mitochondria at the onset of apoptosis

Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane

(2016) Katelyn L. O'Neill et al.   GENES & DEVELOPMENT

Bax/Bak activation in the absence of Bid, Bim, Puma and p53

(2016) J Zhang et al.   Cell Death & Disease

Bcl-2 family of proteins as drug targets for cancer chemotherapy: the long way of BH3 mimetics from bench to bedside

(2015) Laura Vela et al.   CURRENT OPINION IN PHARMACOLOGY

Potent and Specific Peptide Inhibitors of Human Pro-Survival Protein Bcl-x L

(2015) Sanjib Dutta et al.   JOURNAL OF MOLECULAR BIOLOGY

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

(2015) Ariele Viacava Follis et al.   MOLECULAR CELL

Surviving apoptosis: life–death signaling in single cells

(2015) Deborah A. Flusberg et al.   TRENDS IN CELL BIOLOGY

Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax and show no preference for Bak versus Bax

(2015) C Hockings et al.   Cell Death & Disease

The Bcl-2 family: structures, interactions and targets for drug discovery

(2014) Marc Kvansakul et al.   APOPTOSIS

The Proapoptotic Protein tBid Forms Both Superficially Bound and Membrane-Inserted Oligomers

(2014) Sanjeevan Shivakumar et al.   BIOPHYSICAL JOURNAL

Conformational Rearrangements in the Pro-apoptotic Protein, Bax, as It Inserts into Mitochondria

(2014) Robert F. Gahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Many players in BCL-2 family affairs

(2014) Tudor Moldoveanu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid

(2014) A Shamas-Din et al.   Cell Death & Disease

The rheostat in the membrane: BCL-2 family proteins and apoptosis

(2013) N Volkmann et al.   CELL DEATH AND DIFFERENTIATION

Structural Insights of tBid, the Caspase-8-activated Bid, and Its BH3Domain

(2013) Yu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single color FRET based measurements of conformational changes of proteins resulting from translocation inside cells

(2013) Robert F. Gahl et al.   METHODS

Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming

(2013) Barbara Schellenberg et al.   MOLECULAR CELL

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

(2013) Ariele Viacava Follis et al.   Nature Chemical Biology

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The C-terminal helix of Bcl-xL mediates Bax retrotranslocation from the mitochondria

(2012) F Todt et al.   CELL DEATH AND DIFFERENTIATION

Dynamic Interaction of cBid with Detergents, Liposomes and Mitochondria

(2012) Stephanie Bleicken et al.   PLoS One

Mechanisms of Membrane Curvature Sensing

(2011) Bruno Antonny   Annual Review of Biochemistry

Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

(2011) Frank Edlich et al.   CELL

Measuring and Modeling Apoptosis in Single Cells

(2011) Sabrina L. Spencer et al.   CELL

Bax dimerizes via a symmetric BH3:groove interface during apoptosis

(2011) G Dewson et al.   CELL DEATH AND DIFFERENTIATION

BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore

(2011) Loren D. Walensky et al.   TRENDS IN BIOCHEMICAL SCIENCES

Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

(2010) Sylvie Montessuit et al.   CELL

BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane

(2010) Z T Schug et al.   CELL DEATH AND DIFFERENTIATION

FRET Microscopy in 2010: The Legacy of Theodor Förster on the 100th Anniversary of his Birth

(2010) Yuansheng Sun et al.   CHEMPHYSCHEM

Membrane curvature controls dynamin polymerization

(2010) A. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amphipathic helices and membrane curvature

(2009) Guillaume Drin et al.   FEBS LETTERS

Molecular Details of Bax Activation, Oligomerization, and Membrane Insertion

(2009) Stephanie Bleicken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bid: a Bax-like BH3 protein

(2009) L P Billen et al.   ONCOGENE

Imaging endocytic clathrin structures in living cells

(2009) Tom Kirchhausen   TRENDS IN CELL BIOLOGY

Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax

(2008) Jonathan F. Lovell et al.   CELL