Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid

tBid Undergoes Multiple Conformational Changes at the Membrane Required for Bax Activation

(2013) Aisha Shamas-Din et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights of tBid, the Caspase-8-activated Bid, and Its BH3Domain

(2013) Yu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response

(2013) Kristopher A. Sarosiek et al.   MOLECULAR CELL

Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming

(2013) Barbara Schellenberg et al.   MOLECULAR CELL

Mitochondrial Regulation of Cell Death

(2013) S. W. G. Tait et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms of Action of Bcl-2 Family Proteins

(2013) A. Shamas-Din et al.   Cold Spring Harbor Perspectives in Biology

Bid-induced mitochondrial membrane permeabilization waves propagated by local reactive oxygen species (ROS) signaling

(2012) C. Garcia-Perez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of the full-length Bax protein with biomimetic mitochondrial liposomes: A small-angle neutron scattering and fluorescence study

(2011) Dmitri Satsoura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

(2011) Frank Edlich et al.   CELL

Measuring and Modeling Apoptosis in Single Cells

(2011) Sabrina L. Spencer et al.   CELL

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria

(2010) Yehudit Zaltsman et al.   NATURE CELL BIOLOGY

Still embedded together binding to membranes regulates Bcl-2 protein interactions

(2010) B Leber et al.   ONCOGENE

Dynamics of outer mitochondrial membrane permeabilization during apoptosis

(2009) M Rehm et al.   CELL DEATH AND DIFFERENTIATION

Membrane promotes tBID interaction with BCLXL

(2009) Ana J García-Sáez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bid: a Bax-like BH3 protein

(2009) L P Billen et al.   ONCOGENE

Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax

(2008) Jonathan F. Lovell et al.   CELL

Bax targeting to mitochondria occurs via both tail anchor-dependent and -independent mechanisms

(2008) A J Valentijn et al.   CELL DEATH AND DIFFERENTIATION

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax

(2008) Lieven P Billen et al.   PLOS BIOLOGY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY