PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

Site-Directed Methyl Group Labeling as an NMR Probe of Structure and Dynamics in Supramolecular Protein Systems: Applications to the Proteasome and to the ClpP Protease

(2011) Tomasz L. Religa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy

(2011) L. R. Masterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

(2010) D. Ren et al.   SCIENCE

The MDM2-Binding Region in the Transactivation Domain of p53 Also Acts as a Bcl-XL-Binding Motif

(2009) Huibin Xu et al.   BIOCHEMISTRY

BclxL Changes Conformation upon Binding to Wild-type but Not Mutant p53 DNA Binding Domain

(2009) Franz Hagn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

(2009) Hyungjin Kim et al.   MOLECULAR CELL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Dynamic activation of an allosteric regulatory protein

(2009) Shiou-Ru Tzeng et al.   NATURE

Sending Signals Dynamically

(2009) R. G. Smock et al.   SCIENCE

Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1

(2008) Catherine L. Day et al.   JOURNAL OF MOLECULAR BIOLOGY

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

(2008) J. E. Chipuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1

(2008) Callum Smits et al.   STRUCTURE