Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice

Caspase-2 deficiency accelerates chemically induced liver cancer in mice

(2016) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

DNA Damage Response in Hematopoietic Stem Cell Ageing

(2016) Tangliang Li et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd

(2015) L Peintner et al.   CELL DEATH AND DIFFERENTIATION

Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice

(2015) C H Wilson et al.   Cell Death & Disease

Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo

(2014) M R Terry et al.   CELL DEATH AND DIFFERENTIATION

Old, new and emerging functions of caspases

(2014) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

Age-related mutations associated with clonal hematopoietic expansion and malignancies

(2014) Mingchao Xie et al.   NATURE MEDICINE

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

(2014) Giulio Genovese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Caspase-2 protects against oxidative stress in vivo

(2014) S Shalini et al.   ONCOGENE

An unexpected role for caspase-2 in neuroblastoma

(2014) L Dorstyn et al.   Cell Death & Disease

Monoclonal antibody targeting of IL-3 receptor   with CSL362 effectively depletes CML progenitor and stem cells

(2013) E. Nievergall et al.   BLOOD

Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice

(2013) M J Parsons et al.   CELL DEATH AND DIFFERENTIATION

Caspase-2 as a tumour suppressor

(2013) J Puccini et al.   CELL DEATH AND DIFFERENTIATION

Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice

(2013) J. Puccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Reactive Oxygen Species Mark and Influence the Megakaryocyte-Erythrocyte Progenitor Fate of Common Myeloid Progenitors

(2013) Akihito Shinohara et al.   STEM CELLS

Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice

(2012) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

PIDDosome-independent tumor suppression by Caspase-2

(2012) C Manzl et al.   CELL DEATH AND DIFFERENTIATION

Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability

(2012) L Dorstyn et al.   CELL DEATH AND DIFFERENTIATION

Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer

(2011) N. J. Birkbak et al.   CANCER RESEARCH

Chromosomal Instability Substantiates Poor Prognosis in Patients with Diffuse Large B-cell Lymphoma

(2011) S. F. Bakhoum et al.   CLINICAL CANCER RESEARCH

A tumor suppressor function for caspase-2

(2009) L. H. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stems Cells and the Pathways to Aging and Cancer

(2008) Derrick J. Rossi et al.   CELL