Membranolytic anticancer peptides

The effect of amidation on the behaviour of antimicrobial peptides

(2016) Manuela Mura et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

High Selective Performance of Designed Antibacterial and Anticancer Peptide Amphiphiles

(2015) Cuixia Chen et al.   ACS Applied Materials & Interfaces

Multidimensional Design of Anticancer Peptides

(2015) Yen-Chu Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overlap and diversity in antimicrobial peptide databases: compiling a non-redundant set of sequences

(2015) Longendri Aguilera-Mendoza et al.   BIOINFORMATICS

PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties

(2015) Natália Bueno Leite et al.   BIOPHYSICAL JOURNAL

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

A biomimetic approach for enhancing the in vivo half-life of peptides

(2015) Sravan C Penchala et al.   Nature Chemical Biology

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

The increasing role of phosphatidylethanolamine as a lipid receptor in the action of host defence peptides

(2015) David A. Phoenix et al.   PROGRESS IN LIPID RESEARCH

Management of Chemotherapy Induced Nausea and Vomiting in Patients on Multiday Cisplatin Based Combination Chemotherapy

(2015) Praveen Ranganath et al.   Biomed Research International

Peptide-Based Treatment: A Promising Cancer Therapy

(2015) Yu-Feng Xiao et al.   Journal of Immunology Research

Insect antimicrobial peptides and their applications

(2014) Hui-Yu Yi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Killing of melanoma cells and their metastases by human lactoferricin derivatives requires interaction with the cancer marker phosphatidylserine

(2014) Sabrina Riedl et al.   BIOMETALS

Sialic Acids Sweeten a Tumor's Life

(2014) C. Bull et al.   CANCER RESEARCH

Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts

(2014) Lars Erik Uggerhøj et al.   CHEMBIOCHEM

Mechanisms of Resistance Against Cancer Therapeutic Drugs

(2014) Shailja Chatterjee et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

dbaasp: database of antimicrobial activity and structure of peptides

(2014) Giorgi Gogoladze et al.   FEMS MICROBIOLOGY LETTERS

CancerPPD: a database of anticancer peptides and proteins

(2014) Atul Tyagi et al.   NUCLEIC ACIDS RESEARCH

Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa

(2013) Qing-Zhu Yang et al.   ARCHIVES OF PHARMACAL RESEARCH

Future directions for peptide therapeutics development

(2013) Allan A. Kaspar et al.   DRUG DISCOVERY TODAY

Antimicrobial peptides stage a comeback

(2013) Jeffrey L Fox   NATURE BIOTECHNOLOGY

LAMP: A Database Linking Antimicrobial Peptides

(2013) Xiaowei Zhao et al.   PLoS One

Process of inducing pores in membranes by melittin

(2013) M.-T. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From antimicrobial to anticancer peptides. A review

(2013) Diana Gaspar et al.   Frontiers in Microbiology

Membrane potential and cancer progression

(2013) Ming Yang et al.   Frontiers in Physiology

Electrical potentiation of the membrane permeabilization by new peptides with anticancer properties

(2012) Victor V. Lemeshko   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

DADP: the database of anuran defense peptides

(2012) Mario Novković et al.   BIOINFORMATICS

Protease-resistant peptide design-empowering nature's fragile warriors against HIV

(2012) Matthew T. Weinstock et al.   BIOPOLYMERS

Rationale for the use of radiolabelled peptides in diagnosis and therapy

(2012) K. P. Koopmans et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Randomized phase II study of three doses of the integrin inhibitor cilengitide versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer

(2012) Christian Manegold et al.   INVESTIGATIONAL NEW DRUGS

Pardaxin, a Fish Antimicrobial Peptide, Exhibits Antitumor Activity toward Murine Fibrosarcoma in Vitro and in Vivo

(2012) Shu-Ping Wu et al.   Marine Drugs

Host-defense peptides of Australian anurans. Part 2. Structure, activity, mechanism of action, and evolutionary significance

(2012) John H. Bowie et al.   PEPTIDES

The antimicrobial peptide aurein 1.2 disrupts model membranes via the carpet mechanism

(2012) David I. Fernandez et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Antitumor and Angiostatic Activities of the Antimicrobial Peptide Dermaseptin B2

(2012) Hanneke van Zoggel et al.   PLoS One

Integrins as therapeutic targets

(2012) Simon L. Goodman et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Does Cholesterol Play a Role in the Bacterial Selectivity of Antimicrobial Peptides?

(2012) Jeffrey R. Brender et al.   Frontiers in Immunology

In search of a novel target — Phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy

(2011) Sabrina Riedl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antitumor effects and cell selectivity of temporin-1CEa, an antimicrobial peptide from the skin secretions of the Chinese brown frog (Rana chensinensis)

(2011) Che Wang et al.   BIOCHIMIE

Membrane-active host defense peptides – Challenges and perspectives for the development of novel anticancer drugs

(2011) Sabrina Riedl et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Antimicrobial Peptides: Successes, Challenges and Unanswered Questions

(2011) William C. Wimley et al.   JOURNAL OF MEMBRANE BIOLOGY

On the selectivity and efficacy of defense peptides with respect to cancer cells

(2011) Frederick Harris et al.   MEDICINAL RESEARCH REVIEWS

Studies on Mechanism of Action of Anticancer Peptides by Modulation of Hydrophobicity Within a Defined Structural Framework

(2011) Y.-b. Huang et al.   MOLECULAR CANCER THERAPEUTICS

Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells

(2011) Jiřina Slaninová et al.   PEPTIDES

The expanding scope of antimicrobial peptide structures and their modes of action

(2011) Leonard T. Nguyen et al.   TRENDS IN BIOTECHNOLOGY

Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs

(2010) Lenka Monincová et al.   AMINO ACIDS

Pardaxin Permeabilizes Vesicles More Efficiently by Pore Formation than by Disruption

(2010) Brian S. Vad et al.   BIOPHYSICAL JOURNAL

Translating Tumor Antigens into Cancer Vaccines

(2010) Luigi Buonaguro et al.   Clinical and Vaccine Immunology

Homing peptides as targeted delivery vehicles

(2010) Pirjo Laakkonen et al.   Integrative Biology

Peptide-mediated targeted drug delivery

(2010) Sumit Majumdar et al.   MEDICINAL RESEARCH REVIEWS

Antimicrobial peptides: The ancient arm of the human immune system

(2010) Jochen Wiesner et al.   Virulence

Mechanisms of Antimicrobial, Cytolytic, and Cell-Penetrating Peptides: From Kinetics to Thermodynamics

(2009) Paulo F. Almeida et al.   BIOCHEMISTRY

Biopython: freely available Python tools for computational molecular biology and bioinformatics

(2009) P. J. A. Cock et al.   BIOINFORMATICS

Lasioglossins: Three Novel Antimicrobial Peptides from the Venom of the Eusocial BeeLasioglossum laticeps(Hymenoptera: Halictidae)

(2009) Václav Čeřovský et al.   CHEMBIOCHEM

Introduction to Cancer Chemotherapeutics

(2009) Donna S. Shewach et al.   CHEMICAL REVIEWS

Cationic amphiphilic peptides with cancer-selective toxicity

(2009) Frank Schweizer   EUROPEAN JOURNAL OF PHARMACOLOGY

A theoretical analysis of secondary structural characteristics of anticancer peptides

(2009) Sarah R. Dennison et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The effect of C-terminal amidation on the efficacy and selectivity of antimicrobial and anticancer peptides

(2009) Sarah Rachel Dennison et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis

(2009) J. Michael Conlon et al.   TOXICON

Antimicrobial Peptides with Stability toward Tryptic Degradation†

(2008) Johan Svenson et al.   BIOCHEMISTRY

Melittin Interaction with Sulfated Cell Surface Sugars†

(2008) Gabriela Klocek et al.   BIOCHEMISTRY

Mechanism of Antibacterial Action of Dermaseptin B2: Interplay between Helix−Hinge−Helix Structure and Membrane Curvature Strain†

(2008) Cécile Galanth et al.   BIOCHEMISTRY

Cholesterol, lanosterol, and ergosterol attenuate the membrane association of LL-37(W27F) and temporin L

(2008) Rohit Sood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane interactions of antimicrobial peptides from Australian frogs

(2008) David I. Fernandez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Control of cell selectivity of antimicrobial peptides

(2008) Katsumi Matsuzaki   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Magainin 2 in Action: Distinct Modes of Membrane Permeabilization in Living Bacterial and Mammalian Cells

(2008) Yuichi Imura et al.   BIOPHYSICAL JOURNAL

Mechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide

(2008) Hyun Soo Lee et al.   CANCER LETTERS

A Different Molecular Mechanism Underlying Antimicrobial and Hemolytic Actions of Temporins A and L

(2008) Alfonso Carotenuto et al.   JOURNAL OF MEDICINAL CHEMISTRY

APD2: the updated antimicrobial peptide database and its application in peptide design

(2008) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Selective cancer cell cytotoxicity of enantiomeric 9-mer peptides derived from beetle defensins depends on negatively charged phosphatidylserine on the cell surface

(2008) Takashi Iwasaki et al.   PEPTIDES

Studies on anticancer activities of antimicrobial peptides

(2007) David W. Hoskin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES