Tedizolid: The First Once-Daily Oxazolidinone Class Antibiotic

Results of the Surveillance of Tedizolid Activity and Resistance Program: in vitro susceptibility of Gram-positive pathogens collected in 2011 and 2012 from the United States and Europe

(2015) Daniel F. Sahm et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Tedizolid: A new oxazolidinone antimicrobial

(2014) J. J. Kisgen et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Platelet Profile in Patients with Acute Bacterial Skin and Skin Structure Infections Receiving Tedizolid or Linezolid: Findings from the Phase 3 ESTABLISH Clinical Trials

(2014) Thomas P. Lodise et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Analysis of the Phase 3 ESTABLISH Trials of Tedizolid versus Linezolid in Acute Bacterial Skin and Skin Structure Infections

(2014) Andrew F. Shorr et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Executive Summary: Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America

(2014) Dennis L. Stevens et al.   CLINICAL INFECTIOUS DISEASES

In vitro antimicrobial activity of the novel oxazolidinone tedizolid and comparator agents against Staphylococcus aureus and linezolid-resistant Gram-positive pathogens: a multicentre study in China

(2014) Hongbin Chen et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): a randomised, double-blind, phase 3, non-inferiority trial

(2014) Gregory J Moran et al.   LANCET INFECTIOUS DISEASES

Early Experience with Tedizolid: Clinical Efficacy, Pharmacodynamics, and Resistance

(2014) Jeffrey M. Rybak et al.   PHARMACOTHERAPY

In Vitro,In Vivo, and Clinical Studies of Tedizolid To Assess the Potential for Peripheral or Central Monoamine Oxidase Interactions

(2013) S. Flanagan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tedizolid Phosphate for the Management of Acute Bacterial Skin and Skin Structure Infections: Efficacy Summary

(2013) W. O'Riordan et al.   CLINICAL INFECTIOUS DISEASES

Use of Pharmacokinetic/Pharmacodynamic Systems Analyses to Inform Dose Selection of Tedizolid Phosphate

(2013) Thomas P. Lodise et al.   CLINICAL INFECTIOUS DISEASES

Tedizolid for the Management of Human Infections: In Vitro Characteristics

(2013) Jeffrey B. Locke et al.   CLINICAL INFECTIOUS DISEASES

Tedizolid: A Novel Oxazolidinone for Gram-Positive Infections

(2013) Robert C. Moellering   CLINICAL INFECTIOUS DISEASES

Tedizolid Phosphate vs Linezolid for Treatment of Acute Bacterial Skin and Skin Structure Infections

(2013) Philippe Prokocimer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Pharmacokinetics of Tedizolid Following Oral Administration: Single and Multiple Dose, Effect of Food, and Comparison of Two Solid Forms of the Prodrug

(2013) Shawn D. Flanagan et al.   PHARMACOTHERAPY

Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-Resistant and Penicillin-Sensitive Streptococcus pneumoniae

(2012) Sunghak Choi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroActivity and Microbiological Efficacy of Tedizolid (TR-700) against Gram-Positive Clinical Isolates from a Phase 2 Study of Oral Tedizolid Phosphate (TR-701) in Patients with Complicated Skin and Skin Structure Infections

(2012) Philippe Prokocimer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pulmonary Disposition of Tedizolid following Administration of Once-Daily Oral 200-Milligram Tedizolid Phosphate in Healthy Adult Volunteers

(2012) Seth T. Housman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Pharmacodynamics of the New Oxazolidinone Tedizolid Phosphate and Linezolid in a Neutropenic Murine Staphylococcus aureus Pneumonia Model

(2012) Alexander J. Lepak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

ComparativeIn VivoEfficacies of Epithelial Lining Fluid Exposures of Tedizolid, Linezolid, and Vancomycin for Methicillin-Resistant Staphylococcus aureus in a Mouse Pneumonia Model

(2012) Pamela R. Tessier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Chemistry of Peptidyltransferase Center-Targeted Antibiotics: Enzymatic Resistance and Approaches to Countering Resistance

(2011) Kevin P. McCusker et al.   ACS Chemical Biology

The oxazolidinones: past, present, and future

(2011) Karen Joy Shaw et al.   Annals of the New York Academy of Sciences

In VivoPharmacodynamics of Torezolid Phosphate (TR-701), a New Oxazolidinone Antibiotic, against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Strains in a Mouse Thigh Infection Model

(2011) Arnold Louie et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance to Linezolid Caused by Modifications at Its Binding Site on the Ribosome

(2011) Katherine S. Long et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations

(2010) J. B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phase 2, Randomized, Double-Blind, Dose-Ranging Study Evaluating the Safety, Tolerability, Population Pharmacokinetics, and Efficacy of Oral Torezolid Phosphate in Patients with Complicated Skin and Skin Structure Infections

(2010) P. Prokocimer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative In Vitro Antimicrobial Activities of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, Torezolid Phosphate (TR-701), Determination of Tentative Disk Diffusion Interpretive Criteria, and Quality Control Ranges

(2010) S. D. Brown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent

(2009) R. Schaadt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci

(2009) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines

(2009) S. Lemaire et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

(2008) K. J. Shaw et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY