Tedizolid for the Management of Human Infections: In Vitro Characteristics

Tedizolid Phosphate vs Linezolid for Treatment of Acute Bacterial Skin and Skin Structure Infections

(2013) Philippe Prokocimer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

In VitroActivity and Microbiological Efficacy of Tedizolid (TR-700) against Gram-Positive Clinical Isolates from a Phase 2 Study of Oral Tedizolid Phosphate (TR-701) in Patients with Complicated Skin and Skin Structure Infections

(2012) Philippe Prokocimer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pulmonary Disposition of Tedizolid following Administration of Once-Daily Oral 200-Milligram Tedizolid Phosphate in Healthy Adult Volunteers

(2012) Seth T. Housman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Improving known classes of antibiotics: an optimistic approach for the future

(2012) Karen Bush   CURRENT OPINION IN PHARMACOLOGY

LEADER Surveillance program results for 2010: an activity and spectrum analysis of linezolid using 6801 clinical isolates from the United States (61 medical centers)

(2012) Robert K. Flamm et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Tedizolid (TR-701): a new oxazolidinone with enhanced potency

(2012) Zeina A. Kanafani et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Resistance to linezolid in a methicillin-susceptible Staphylococcus aureus clinical isolate without previous exposure to oxazolidinones

(2012) Immaculada Quiles-Melero et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The emerging problem of linezolid-resistant Staphylococcus

(2012) B. Gu et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Chemistry of Peptidyltransferase Center-Targeted Antibiotics: Enzymatic Resistance and Approaches to Countering Resistance

(2011) Kevin P. McCusker et al.   ACS Chemical Biology

The oxazolidinones: past, present, and future

(2011) Karen Joy Shaw et al.   Annals of the New York Academy of Sciences

Low Fitness Cost of the Multidrug Resistance Genecfr

(2011) Jacqueline M. LaMarre et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic Environment and Stability ofcfrin Methicillin-Resistant Staphylococcus aureus CM05

(2011) Jeffrey B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance to Linezolid Caused by Modifications at Its Binding Site on the Ribosome

(2011) Katherine S. Long et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent

(2011) Weon Bin Im et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Management of serious meticillin-resistant Staphylococcus aureus infections: what are the limits?

(2011) Ian M. Gould et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

MRSA: the first half century

(2011) R. C. Moellering   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative In Vitro Activities of Torezolid (DA-7157) against Clinical Isolates of Aerobic and Anaerobic Bacteria in South Korea

(2010) J. H. Yum et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations

(2010) J. B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Activities of TR-700 (Torezolid) against Staphylococcal Blood Isolates Collected in Spain

(2010) C. Betriu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Elevated Linezolid Resistance in Clinical cfr-Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3

(2010) J. B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative In Vitro Antimicrobial Activities of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, Torezolid Phosphate (TR-701), Determination of Tentative Disk Diffusion Interpretive Criteria, and Quality Control Ranges

(2010) S. D. Brown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent

(2009) R. Schaadt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

(2009) J. B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

(2009) J. B. Locke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens

(2009) R. N. Jones et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci

(2009) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines

(2009) S. Lemaire et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of novel oxazolidinones against Nocardia brasiliensis growing within THP-1 macrophages

(2009) L. Vera-Cabrera et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

(2008) K. J. Shaw et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Transcriptional and Translational Control of the mlr Operon, Which Confers Resistance to Seven Classes of Protein Synthesis Inhibitors

(2008) L. K. Smith et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY