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GRIM-19 expression is a potent prognostic marker in colorectal cancer

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Gefitinib-mediated Reactive Oxygen Specie (ROS) Instigates Mitochondrial Dysfunction and Drug Resistance in Lung Cancer Cells

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DACH1 inhibits lung adenocarcinoma invasion and tumor growth by repressing CXCL5 signaling

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DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling

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Autophagy and apoptosis: where do they meet?

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DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells

(2014) Qian Chu et al.   Journal of Hematology & Oncology

Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-α-mediated signaling

(2014) X Peng et al.   Cell Death & Disease

GRIM-19 opposes reprogramming of glioblastoma cell metabolism via HIF1α destabilization

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Pharmacological approaches to restore mitochondrial function

(2013) Pénélope A. Andreux et al.   NATURE REVIEWS DRUG DISCOVERY

Suppression of Mitochondrial Complex I Influences Cell Metastatic Properties

(2013) Xuelian He et al.   PLoS One

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

(2013) X Sui et al.   Cell Death & Disease

Function of GRIM-19, a Mitochondrial Respiratory Chain Complex I Protein, in Innate Immunity

(2012) Yong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial complex I: A central regulator of the aging process

(2011) Rhoda Stefanatos et al.   CELL CYCLE

Identification of alternatively spliced GRIM-19 mRNA in kidney cancer tissues

(2010) Xuelian He et al.   JOURNAL OF HUMAN GENETICS

Autophagy: Snapshot of the network

(2010) Beth Levine et al.   NATURE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

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