GRIM-19 opposes reprogramming of glioblastoma cell metabolism via HIF1α destabilization

STAT3 can serve as a hit in the process of malignant transformation of primary cells

(2012) M Demaria et al.   CELL DEATH AND DIFFERENTIATION

Links between metabolism and cancer

(2012) C. V. Dang   GENES & DEVELOPMENT

Downregulation of GRIM-19 promotes growth and migration of human glioma cells

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Upregulation of the GRIM-19 gene suppresses invasion and metastasis of human gastric cancer SGC-7901 cell line

(2010) Yi Huang et al.   EXPERIMENTAL CELL RESEARCH

Gene associated with retinoid–interferon-induced mortality-19 suppresses growth of lung adenocarcinoma tumor in vitro and in vivo

(2010) Tong Wang et al.   LUNG CANCER

Overexpression of GRIM-19 in Cancer Cells Suppresses STAT3-Mediated Signal Transduction and Cancer Growth

(2010) Takashi Okamoto et al.   MOLECULAR CANCER THERAPEUTICS

Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism

(2009) I. Samudio et al.   CANCER RESEARCH

Down-Regulation of GRIM-19 Expression Is Associated With Hyperactivation of STAT3-Induced Gene Expression and Tumor Growth in Human Cervical Cancers

(2009) Ying Zhou et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Warburg Effect Suppresses Oxidative Stress Induced Apoptosis in a Yeast Model for Cancer

(2009) Christoph Ruckenstuhl et al.   PLoS One

Mitochondria and cancer

(2009) Valdemar Máximo et al.   VIRCHOWS ARCHIV

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION

Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

(2008) Ralph J Deberardinis   GENETICS IN MEDICINE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE