RAD51 regulates CHK1 stability via autophagy to promote cell growth in esophageal squamous carcinoma cells

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NRAGE is involved in homologous recombination repair to resist the DNA-damaging chemotherapy and composes a ternary complex with RNF8–BARD1 to promote cell survival in squamous esophageal tumorigenesis

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Cellular Retinoic Acid Binding Protein 2 Is Strikingly Downregulated in Human Esophageal Squamous Cell Carcinoma and Functions as a Tumor Suppressor

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Effects of Rad51 on Survival of A549 Cells

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ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells

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Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response

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Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

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NRAGE promotes cell proliferation by stabilizing PCNA in a ubiquitin–proteasome pathway in esophageal carcinomas

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Torc1/Torc2 inhibitor, Palomid 529, enhances radiation response modulating CRM1-mediated survivin function and delaying DNA repair in prostate cancer models

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Rad51 Expression Is a Useful Predictive Factor for the Efficacy of Neoadjuvant Chemoradiotherapy in Squamous Cell Carcinoma of the Esophagus

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Systematic Screen Identifies miRNAs That Target RAD51 and RAD51D to Enhance Chemosensitivity

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Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage

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Autophagy and cancer

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RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma

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Akt1 inhibits homologous recombination in Brca1-deficient cells by blocking the Chk1-Rad51 pathway

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Elevated expression of Rad51 is correlated with decreased survival in resectable esophageal squamous cell carcinoma

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Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome

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Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition

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Knockdown of Rad51 expression induces radiation- and chemo-sensitivity in osteosarcoma cells

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Overexpression of RAD51 occurs in aggressive prostatic cancer

(2009) Anita Mitra et al.   HISTOPATHOLOGY

Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

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Mechanism of Eukaryotic Homologous Recombination

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