IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells

Tumor Heterogeneity--A 'Contemporary Concept Founded on Historical Insights and Predictions

(2016) D. R. Welch   CANCER RESEARCH

mRNAs that specifically interact with eukaryotic ribosomal subunits

(2015) Jules Deforges et al.   BIOCHIMIE

Small molecule inhibitors of IRES-mediated translation

(2015) Christos Vaklavas et al.   CANCER BIOLOGY & THERAPY

Elimination of ALDH+ breast tumor initiating cells by docosahexanoic acid and/or gamma tocotrienol through SHP-1 inhibition of Stat3 signaling

(2015) Ailian Xiong et al.   MOLECULAR CARCINOGENESIS

Intratumoral Heterogeneity in a Trp53-Null Mouse Model of Human Breast Cancer

(2015) M. Zhang et al.   Cancer Discovery

Quorum sensing peptides mediating interspecies bacterial cell death as a novel class of antimicrobial agents

(2014) Sathish Kumar et al.   CURRENT OPINION IN MICROBIOLOGY

Cell-to-cell variability in cell death: can systems biology help us make sense of it all?

(2014) X Xia et al.   Cell Death & Disease

Cell death by cornification

(2013) Leopold Eckhart et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Peroxisome proliferator-activated receptor-α activation protects against endoplasmic reticulum stress-induced HepG2 cell apoptosis

(2013) Wei-xiang Tang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Metrics other than potency reveal systematic variation in responses to cancer drugs

(2013) Mohammad Fallahi-Sichani et al.   Nature Chemical Biology

Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity

(2012) S. E. Little et al.   CANCER RESEARCH

MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27KIP1

(2012) M T Gómez-Casares et al.   ONCOGENE

Localized IRES-Dependent Translation of ER Chaperone Protein mRNA in Sensory Axons

(2012) Almudena Pacheco et al.   PLoS One

Aberrant expression of c-Jun in glioblastoma by internal ribosome entry site (IRES)-mediated translational activation

(2012) L. Blau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structures of nonprotein-coding RNAs that drive internal ribosome entry site function

(2012) Terra-Dawn M. Plank et al.   Wiley Interdisciplinary Reviews-RNA

Far upstream element binding protein 1 activates translation of p27Kip1 mRNA through its internal ribosomal entry site

(2011) Yuhuan Zheng et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Dose-response curve slope is a missing dimension in the analysis of HIV-1 drug resistance

(2011) M. E. S. Sampah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of a Quorum Sensing mechanism triggers tumorigenesis: a simple discrete model corroborated by experiments in mammary cancer stem cells

(2010) Zvia Agur et al.   Biology Direct

Homotypic Gap Junctional Communication Associated with Metastasis Suppression Increases with PKA Activity and Is Unaffected by PI3K Inhibition

(2010) T. M. Bodenstine et al.   CANCER RESEARCH

A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

(2010) Jonghwan Kim et al.   CELL

Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

(2010) Salvatore Pece et al.   CELL

Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES

(2010) Scott W. Blume et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Differentiation therapy of leukemia: 3 decades of development

(2009) D. Nowak et al.   BLOOD

A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP

(2009) Xiangjun Meng et al.   CANCER RESEARCH

Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor Inhibition

(2009) N. A. Dallas et al.   CANCER RESEARCH

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

(2009) Emmanuelle Charafe-Jauffret et al.   CANCER RESEARCH

Myc's other life: stem cells and beyond

(2009) Elisa Laurenti et al.   CURRENT OPINION IN CELL BIOLOGY

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis

(2008) Jonathan Hickson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Alterations in RNA-binding activities of IRES-regulatory proteins as a mechanism for physiological variability and pathological dysregulation of IGF-IR translational control in human breast tumor cells

(2008) Zheng Meng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

(2008) Jialiang Wang et al.   PLoS One

Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts

(2008) K. B. Horwitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA