MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27KIP1

Second-Generation Tyrosine Kinase Inhibitors: The Future of Frontline CML Therapy

(2011) H. M. Kantarjian et al.   CLINICAL CANCER RESEARCH

SKP2 Oncogene Is a Direct MYC Target Gene and MYC Down-regulates p27KIP1through SKP2 in Human Leukemia Cells

(2011) Gabriel Bretones et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MYC in Chronic Myeloid Leukemia: Induction of Aberrant DNA Synthesis and Association with Poor Response to Imatinib

(2011) M. Albajar et al.   MOLECULAR CANCER RESEARCH

Global Phosphoproteomics Reveals Crosstalk Between Bcr-Abl and Negative Feedback Mechanisms Controlling Src Signaling

(2011) L. Rubbi et al.   Science Signaling

Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype

(2010) Srirupa Roy et al.   CELL CYCLE

Inhibition of cell differentiation: A critical mechanism for MYC-mediated carcinogenesis?

(2010) Javier Leon et al.   CELL CYCLE

Novel dual Src/Abl inhibitors for hematologic and solid malignancies

(2010) Silvia Schenone et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Transcriptional activation of Skp2 by BCR-ABL in K562 chronic myeloid leukemia cells

(2009) Jing-Yi Chen et al.   LEUKEMIA RESEARCH

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease

(2008) A. Agarwal et al.   BLOOD

Molecular biology of bcr-abl1-positive chronic myeloid leukemia

(2008) A. Quintas-Cardama et al.   BLOOD

Transient Potent BCR-ABL Inhibition Is Sufficient to Commit Chronic Myeloid Leukemia Cells Irreversibly to Apoptosis

(2008) Neil P. Shah et al.   CANCER CELL

PU.1 expression is restored upon treatment of chronic myeloid leukemia patients

(2008) Marta Albajar et al.   CANCER LETTERS

Myc's broad reach

(2008) M. Eilers et al.   GENES & DEVELOPMENT

Chronic Myeloid Leukemia Stem Cells

(2008) Edward Kavalerchik et al.   JOURNAL OF CLINICAL ONCOLOGY

Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase

(2008) Ji Wu et al.   JNCI-Journal of the National Cancer Institute

Myc Inhibits p27-Induced Erythroid Differentiation of Leukemia Cells by Repressing Erythroid Master Genes without Reversing p27-Mediated Cell Cycle Arrest

(2008) J. C. Acosta et al.   MOLECULAR AND CELLULAR BIOLOGY