A framework forin vitrosystems toxicology assessment of e-liquids

Counseling patients with asthma and allergy about electronic cigarettes: an evidence-based approach

(2016) Riccardo Polosa et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Characterization of potential impurities and degradation products in electronic cigarette formulations and aerosols

(2016) Jason W. Flora et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

E-cigarettes generate high levels of aldehydes only in ‘dry puff’ conditions

(2015) Konstantinos E. Farsalinos et al.   ADDICTION

The Need for More E-Cigarette Data: A Call to Action

(2015) Laura Crotty Alexander et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cilia Dysfunction in Lung Disease

(2015) Ann E. Tilley et al.   Annual Review of Physiology

High-Content Assays for Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures

(2015) Oksana Sirenko et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette

(2015) Ignacio Gonzalez-Suarez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Aerosol deposition doses in the human respiratory tree of electronic cigarette smokers

(2015) Maurizio Manigrasso et al.   ENVIRONMENTAL POLLUTION

Electronic Nicotine Delivery Systems: A Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology

(2015) Thomas H. Brandon et al.   JOURNAL OF CLINICAL ONCOLOGY

An approach to ingredient screening and toxicological risk assessment of flavours in e-liquids

(2015) S. Costigan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Flavour chemicals in electronic cigarette fluids

(2015) Peyton A Tierney et al.   TOBACCO CONTROL

Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts

(2015) Anita R. Iskandar et al.   TOXICOLOGICAL SCIENCES

Systems Biology Reveals Cigarette Smoke-Induced Concentration-Dependent Direct and Indirect Mechanisms That Promote Monocyte–Endothelial Cell Adhesion

(2015) Carine Poussin et al.   TOXICOLOGICAL SCIENCES

Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells

(2015) U. Kogel et al.   TOXICOLOGY IN VITRO

Toxicity testing in the 21st century beyond environmental chemicals

(2015) Costanza Rovida   ALTEX-Alternatives to Animal Experimentation

Variations in Label Information and Nicotine Levels in Electronic Cigarette Refill Liquids in South Korea: Regulation Challenges

(2015) Sungroul Kim et al.   International Journal of Environmental Research and Public Health

Evaluation of E-Cigarette Liquid Vapor and Mainstream Cigarette Smoke after Direct Exposure of Primary Human Bronchial Epithelial Cells

(2015) Stefanie Scheffler et al.   International Journal of Environmental Research and Public Health

Puffing Topography and Nicotine Intake of Electronic Cigarette Users

(2015) Rachel Z. Behar et al.   PLoS One

Vapors Produced by Electronic Cigarettes and E-Juices with Flavorings Induce Toxicity, Oxidative Stress, and Inflammatory Response in Lung Epithelial Cells and in Mouse Lung

(2015) Chad A. Lerner et al.   PLoS One

Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

(2014) Florian Martin et al.   BMC BIOINFORMATICS

Systems Toxicology: From Basic Research to Risk Assessment

(2014) Shana J. Sturla et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Systems Biology Approach for Evaluating the Biological Impact of Environmental Toxicants in Vitro

(2014) Ignacio Gonzalez-Suarez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Toxicological evaluation of aerosols of a tobacco extract formulation and nicotine formulation in acute and short-term inhalation studies

(2014) Michael S. Werley et al.   INHALATION TOXICOLOGY

The Response of Human Nasal and Bronchial Organotypic Tissue Cultures to Repeated Whole Cigarette Smoke Exposure

(2014) Marja Talikka et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Carbonyl Compounds in Electronic Cigarette Vapors: Effects of Nicotine Solvent and Battery Output Voltage

(2014) Leon Kosmider et al.   NICOTINE & TOBACCO RESEARCH

Effects of User Puff Topography, Device Voltage, and Liquid Nicotine Concentration on Electronic Cigarette Nicotine Yield: Measurements and Model Predictions

(2014) Soha Talih et al.   NICOTINE & TOBACCO RESEARCH

Nicotine Concentrations in Electronic Cigarette Refill and Do-It-Yourself Fluids

(2014) B. Davis et al.   NICOTINE & TOBACCO RESEARCH

The Chemical Components of Electronic Cigarette Cartridges and Refill Fluids: Review of Analytical Methods

(2014) M. Famele et al.   NICOTINE & TOBACCO RESEARCH

Electronic Nicotine Delivery Systems (“E-cigarettes”)

(2014) Paul Truman Harrell et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Electronic Cigarette Liquid Increases Inflammation and Virus Infection in Primary Human Airway Epithelial Cells

(2014) Qun Wu et al.   PLoS One

Electronic cigarettes in the USA: a summary of available toxicology data and suggestions for the future: Table 1

(2014) Michael S Orr   TOBACCO CONTROL

Electronic cigarettes: product characterisation and design considerations

(2014) Christopher J Brown et al.   TOBACCO CONTROL

Four hundred and sixty brands of e-cigarettes and counting: implications for product regulation

(2014) Shu-Hong Zhu et al.   TOBACCO CONTROL

Electronic cigarettes: human health effects

(2014) Priscilla Callahan-Lyon   TOBACCO CONTROL

In vitrosystems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures

(2014) Walter K. Schlage et al.   TOXICOLOGY MECHANISMS AND METHODS

Comparative In Vitro Toxicity Profile of Electronic and Tobacco Cigarettes, Smokeless Tobacco and Nicotine Replacement Therapy Products: E-Liquids, Extracts and Collected Aerosols

(2014) Manoj Misra et al.   International Journal of Environmental Research and Public Health

High-throughput Image Analysis of Tumor Spheroids: A User-friendly Software Application to Measure the Size of Spheroids Automatically and Accurately

(2014) Wenjin Chen et al.   Jove-Journal of Visualized Experiments

Tobacco harm reduction: The need for new products that can compete with cigarettes

(2013) Karl Olov Fagerström et al.   ADDICTIVE BEHAVIORS

Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers

(2013) Carole Mathis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Case study: the role of mechanistic network models in systems toxicology

(2013) Julia Hoeng et al.   DRUG DISCOVERY TODAY

A review of in vitro cigarette smoke exposure systems

(2013) David Thorne et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

What should it take to describe a substance or product as 'sperm-safe'

(2013) D. Mortimer et al.   HUMAN REPRODUCTION UPDATE

Cytotoxicity evaluation of electronic cigarette vapor extract on cultured mammalian fibroblasts (ClearStream-LIFE): comparison with tobacco cigarette smoke extract

(2013) Giorgio Romagna et al.   INHALATION TOXICOLOGY

Modelling and measurement of particle deposition for cell exposure at the air–liquid interface

(2013) Andreas Comouth et al.   JOURNAL OF AEROSOL SCIENCE

Quantitative assessment of biological impact using transcriptomic data and mechanistic network models

(2013) Ty M. Thomson et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Comparison of the Cytotoxic Potential of Cigarette Smoke and Electronic Cigarette Vapour Extract on Cultured Myocardial Cells

(2013) Konstantinos Farsalinos et al.   International Journal of Environmental Research and Public Health

Respiratory and Olfactory Cytotoxicity of Inhaled 2,3-Pentanedione in Sprague-Dawley Rats

(2012) Ann F. Hubbs et al.   AMERICAN JOURNAL OF PATHOLOGY

Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks

(2012) Florian Martin et al.   BMC Systems Biology

Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells

(2012) JeanClare Seagrave et al.   RESPIRATORY RESEARCH

High-Throughput Library Screening Identifies Two NovelNQO1Inducers in Human Lung Cells

(2011) Xiang-Lin Tan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Nanotoxicology: in Vitro–in Vivo Dosimetry

(2011) Günter Oberdörster   ENVIRONMENTAL HEALTH PERSPECTIVES

Epithelial cells and airway diseases

(2011) David Proud et al.   IMMUNOLOGICAL REVIEWS

In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung—A dialog between aerosol science and biology

(2011) Hanns-Rudolf Paur et al.   JOURNAL OF AEROSOL SCIENCE

Toxicology in the 21st century – Working our way towards a visionary reality

(2011) Ninna Berg et al.   TOXICOLOGY IN VITRO

Frozen robust multiarray analysis (fRMA)

(2010) M. N. McCall et al.   BIOSTATISTICS

Evaluation of In vitro Assays for Assessing the Toxicity of Cigarette Smoke and Smokeless Tobacco

(2009) M. D. Johnson et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Exposure as Part of a Systems Approach for Assessing Risk

(2009) Linda S. Sheldon et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Is inflammation a consequence of extracellular hyperosmolarity?

(2009) Laurent Schwartz et al.   Journal of Inflammation-London

Soluble Intercellular Adhesion Molecule-1 and E-selectin in Patients with Asthma Exacerbation

(2009) Mahdi Bijanzadeh et al.   LUNG

Smoking Is Associated with Shortened Airway Cilia

(2009) Philip L. Leopold et al.   PLoS One

Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD

(2009) A Di Stefano et al.   THORAX

Cigarette smoke combined with Toll-like receptor 3 signaling triggers exaggerated epithelial regulated upon activation, normal T-cell expressed and secreted/CCL5 expression in chronic rhinosinusitis

(2008) Moshe Yamin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CXCR3 and CCR5 Chemokines in Induced Sputum From Patients With COPD

(2007) Claudia Costa et al.   CHEST