The Response of Human Nasal and Bronchial Organotypic Tissue Cultures to Repeated Whole Cigarette Smoke Exposure

Analysis of the Roles of Smoking and Allergy in Nasal Polyposis

(2014) Orhan Görgülü et al.   ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY

Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers

(2013) Carole Mathis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Young “Healthy” Smokers Have Functional and Inflammatory Changes in the Nasal and the Lower Airways

(2013) Marina Lazzari Nicola et al.   CHEST

Nasal epithelial repair and remodeling in physical injury, infection, and inflammatory diseases

(2013) Yan Yan et al.   Current Opinion in Otolaryngology & Head and Neck Surgery

Case study: the role of mechanistic network models in systems toxicology

(2013) Julia Hoeng et al.   DRUG DISCOVERY TODAY

Blocking of thromboxane A2 receptor attenuates airway mucus hyperproduction induced by cigarette smoke

(2013) Jing An et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Quantitative assessment of biological impact using transcriptomic data and mechanistic network models

(2013) Ty M. Thomson et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative stress and innate immunity responses in cigarette smoke stimulated nasal epithelial cells

(2013) Elisabetta Pace et al.   TOXICOLOGY IN VITRO

DNA adducts and the total sum of at-risk DNA repair alleles in the nasal epithelium, a target tissue of tobacco smoking-associated carcinogenesis

(2013) Marco E. M. Peluso et al.   Toxicology Research

Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks

(2012) Florian Martin et al.   BMC Systems Biology

Real-time assessment of cigarette smoke particle deposition in vitro

(2012) Jason Adamson et al.   Chemistry Central Journal

Sinonasal inflammation in COPD: a systematic review: Table 1–

(2012) Kåre Håkansson et al.   EUROPEAN RESPIRATORY JOURNAL

Hyaluronan and Layilin Mediate Loss of Airway Epithelial Barrier Function Induced by Cigarette Smoke by Decreasing E-cadherin

(2012) Rosanna Malbran Forteza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Obstructive Pulmonary Disease and Risk of Lung Cancer: The Importance of Smoking and Timing of Diagnosis

(2012) Helen A. Powell et al.   Journal of Thoracic Oncology

Potential of in vitro reconstituted 3D human airway epithelia (MucilAir™) to assess respiratory sensitizers

(2012) Song Huang et al.   TOXICOLOGY IN VITRO

Characterization of the Retrocyclin Analogue RC-101 as a Preventative of Staphylococcus aureus Nasal Colonization

(2011) Ryan P. Lamers et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Regulation of Cigarette Smoke-Induced Mucin Expression by Neuregulin1β/ErbB3 Signalling in Human Airway Epithelial Cells

(2011) Hongmei Yu et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Proteomic profiling of human respiratory epithelia by iTRAQ reveals biomarkers of exposure and harm by tobacco smoke components

(2011) Keith Sexton et al.   BIOMARKERS

Construction of a computable cell proliferation network focused on non-diseased lung cells

(2011) Jurjen W Westra et al.   BMC Systems Biology

A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue

(2011) Walter K Schlage et al.   BMC Systems Biology

A network-based approach to quantifying the impact of biologically active substances

(2011) Julia Hoeng et al.   DRUG DISCOVERY TODAY

Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery

(2011) I. H. Heijink et al.   EUROPEAN RESPIRATORY JOURNAL

Accelerating the Development of 21st-Century Toxicology: Outcome of a Human Toxicology Project Consortium Workshop

(2011) Martin L. Stephens et al.   TOXICOLOGICAL SCIENCES

MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium

(2010) Maria E. Monzon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

(2010) Alejandro A. Pezzulo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Do Airway Epithelium Air–Liquid Cultures Represent theIn VivoAirway Epithelium Transcriptome?

(2010) Anna Dvorak et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mutagenicity of 11 cigarette smoke condensates in two versions of the mouse lymphoma assay

(2010) X. Guo et al.   MUTAGENESIS

Human primary bronchial lung cell constructs: The new respiratory models

(2010) Kelly BéruBé et al.   TOXICOLOGY

Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: A potential model of goblet cell hyperplasia

(2010) Linsey E. Haswell et al.   TOXICOLOGY IN VITRO

Bronchial Airway Epithelial Cell Damage Following Exposure to Cigarette Smoke Includes Disassembly of Tight Junction Components Mediated by the Extracellular Signal-Regulated Kinase 1/2 Pathway

(2009) Loredana Petecchia et al.   CHEST

Nasal and sinus involvement in chronic obstructive pulmonary disease

(2009) Jung-Soo Kim et al.   CURRENT OPINION IN PULMONARY MEDICINE

Histopathological changes of the nasal mucosa induced by smoking

(2009) Tuvia Hadar et al.   INHALATION TOXICOLOGY

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium

(2009) Xiaoling Zhang et al.   PHYSIOLOGICAL GENOMICS

Nasal Epithelial Cells as Surrogates for Bronchial Epithelial Cells in Airway Inflammation Studies

(2008) Catherine M. McDougall et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium

(2008) Sriram Sridhar et al.   BMC GENOMICS

Subversion of interleukin-1-mediated host defence by a nasal carrier strain ofStaphylococcus aureus

(2008) Gerry A. Quinn et al.   IMMUNOLOGY

Genomic biomarkers of pulmonary exposure to tobacco smoke components

(2008) Keith Sexton et al.   Pharmacogenetics and Genomics

Smoke chemistry, in vitro and in vivo toxicology evaluations of the electrically heated cigarette smoking system series K

(2008) Michael S. Werley et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Epigallocatechin-3-gallate inhibits interleukin-1β-induced MUC5AC gene expression and MUC5AC secretion in normal human nasal epithelial cells

(2007) Hyun Jik Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY