From the Cover: Manganese Stimulates Mitochondrial H2O2Production in SH-SY5Y Human Neuroblastoma Cells Over Physiologic as well as Toxicologic Range

Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications

(2015) Nadezda Apostolova et al.   ANTIOXIDANTS & REDOX SIGNALING

N-acetylcysteineamide protects against manganese-induced toxicity in SHSY5Y cell line

(2015) Yasaswi Maddirala et al.   BRAIN RESEARCH

Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity

(2015) Christina Dimovasili et al.   NEUROCHEMISTRY INTERNATIONAL

Manganese-Induced Parkinsonism and Parkinson’s Disease: Shared and Distinguishable Features

(2015) Gunnar Kwakye et al.   International Journal of Environmental Research and Public Health

Role of Metabolic H2O2Generation

(2014) Helmut Sies   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Toxic Effects of Aβ Through Mitofusins in the Early Pathogenesis of Alzheimer’s Disease

(2014) Zhaofei Wu et al.   MOLECULAR NEUROBIOLOGY

Considerations on manganese (Mn) treatments for in vitro studies

(2014) Aaron B. Bowman et al.   NEUROTOXICOLOGY

Redox-Optimized ROS Balance and the relationship between mitochondrial respiration and ROS

(2013) Sonia Cortassa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells

(2013) Christine C. Winterbourn   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selective Metabolism of Hypothiocyanous Acid by Mammalian Thioredoxin Reductase Promotes Lung Innate Immunity and Antioxidant Defense

(2013) Joshua D. Chandler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans

(2013) Julia Bornhorst et al.   Metallomics

Complex II of the Mitochondrial Respiratory Chain Is the Key Mediator of Divalent Manganese-Induced Hydrogen Peroxide Production in Microglia

(2013) Yue Liu et al.   TOXICOLOGICAL SCIENCES

Methods for Detection of Mitochondrial and Cellular Reactive Oxygen Species

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Impact of Manganese on and Transfer across Blood-Brain and Blood-Cerebrospinal Fluid Barrierin Vitro

(2012) Julia Bornhorst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects

(2012) Asad A. Aboud et al.   NEUROTOXICOLOGY

Interaction of manganese(II) complex with apotransferrin and the apotransferrin enhanced anticancer activities

(2012) Ling Yao et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Hidden Costs of Energy: Unpriced Consequences of Energy Production and Use by the National Research Council . Washington, DC:National Academies Press, 2010. 473 pp. ISBN: 978-0-309-14640-1, $47  

(2011) Maximilian Auffhammer   ENVIRONMENTAL HEALTH PERSPECTIVES

Ingestion of Mn and Pb by rats during and after pregnancy alters iron metabolism and behavior in offspring

(2011) Ramon M. Molina et al.   NEUROTOXICOLOGY

Maneb and Paraquat-Mediated Neurotoxicity: Involvement of Peroxiredoxin/Thioredoxin System

(2011) James R. Roede et al.   TOXICOLOGICAL SCIENCES

The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronal death: ER stress and mitochondrial complexes

(2011) Hyonok Yoon et al.   TOXICOLOGY IN VITRO

What does the commonly used DCF test for oxidative stress really show?

(2010) Markus Karlsson et al.   BIOCHEMICAL JOURNAL

Elevated manganese and cognitive performance in school-aged children and their mothers

(2010) José A. Menezes-Filho et al.   ENVIRONMENTAL RESEARCH

Early Postnatal Blood Manganese Levels and Childrenʼs Neurodevelopment

(2010) Birgit Claus Henn et al.   EPIDEMIOLOGY

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

A key role for mitochondria in endothelial signaling by plasma cysteine/cystine redox potential

(2009) Young-Mi Go et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria Are the Source of Hydrogen Peroxide for Dynamic Brain-Cell Signaling

(2009) L. Bao et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Estimating the prevalence of clinical manganism using a cascaded screening process in a South African manganese smelter

(2009) J.E. Myers et al.   NEUROTOXICOLOGY

Effects of copper on the photosynthesis of intact chloroplasts: interaction with manganese

(2009) Mário Pádua et al.   PHYSIOLOGIA PLANTARUM

Gene and Protein Responses of Human Monocytes to Extracellular Cysteine Redox Potential

(2009) Young-Mi Go et al.   TOXICOLOGICAL SCIENCES

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

(2009) Dejan Milatovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Radical-free biology of oxidative stress

(2008) Dean P. Jones   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Manganese Neurotoxicity: Lessons Learned from Longitudinal Studies in Nonhuman Primates

(2008) Neal C. Burton et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Arsenic accumulation, elimination, and interaction with copper, zinc and manganese in liver and kidney of rats

(2008) Xing Cui et al.   FOOD AND CHEMICAL TOXICOLOGY

Effect of Chronic Low Level Manganese Exposure on Postural Balance: A Pilot Study of Residents in Southern Ohio

(2008) J Shawn. Standridge et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE