Complex II of the Mitochondrial Respiratory Chain Is the Key Mediator of Divalent Manganese-Induced Hydrogen Peroxide Production in Microglia

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of dopaminergic neuronal cystatin C in neuronal injury-induced microglial activation and neurotoxicity

(2012) Garima Dutta et al.   JOURNAL OF NEUROCHEMISTRY

Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction

(2010) A Lemarie et al.   CELL DEATH AND DIFFERENTIATION

Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates

(2010) Tatyana Verina et al.   NEUROTOXICOLOGY

An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays

(2010) Thomas E. Gunter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Microglia enhance manganese chloride-induced dopaminergic neurodegeneration: Role of free radical generation

(2009) Ping Zhang et al.   EXPERIMENTAL NEUROLOGY

Synergistic dopaminergic neurotoxicity of manganese and lipopolysaccharide: differential involvement of microglia and astroglia

(2009) Ping Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Manganese and its Role in Parkinson’s Disease: From Transport to Neuropathology

(2009) Michael Aschner et al.   NEUROMOLECULAR MEDICINE

The case for manganese interaction with mitochondria

(2009) Thomas E. Gunter et al.   NEUROTOXICOLOGY

Manganese Neurotoxicity: Lessons Learned from Longitudinal Studies in Nonhuman Primates

(2008) Neal C. Burton et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Manganese accumulates primarily in nuclei of cultured brain cells

(2008) Kiran Kalia et al.   NEUROTOXICOLOGY

Manganese Induces Dopaminergic Neurodegeneration via Microglial Activation in a Rat Model of Manganism

(2008) Fang Zhao et al.   TOXICOLOGICAL SCIENCES

Sub-cellular localization of manganese in the basal ganglia of normal and manganese-treated rats

(2007) M. Morello et al.   NEUROTOXICOLOGY