From the Cover: Zinc Deficiency Worsens and Supplementation Prevents High-Fat Diet Induced Vascular Inflammation, Oxidative Stress, and Pathological Remodeling

Impaired recovery from peritoneal inflammation in a mouse model of mild dietary zinc restriction

(2016) Brett E. Phillips et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Zinc delays the progression of obesity-related glomerulopathy in mice via down-regulating P38 MAPK-mediated inflammation

(2016) Manyu Luo et al.   Obesity

Lifetime risk: childhood obesity and cardiovascular risk

(2015) J. Ayer et al.   EUROPEAN HEART JOURNAL

The role of antioxidants in the chemistry of oxidative stress: A review

(2015) Aurelia Magdalena Pisoschi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Metallothionein plays a prominent role in the prevention of diabetic nephropathy by sulforaphane via up-regulation of Nrf2

(2015) Hao Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of Nrf2 in oxidative stress-induced endothelial injuries

(2015) B. Chen et al.   JOURNAL OF ENDOCRINOLOGY

Zinc treatment prevents type 1 diabetes-induced hepatic oxidative damage, endoplasmic reticulum stress, and cell death, and even prevents possible steatohepatitis in the OVE26 mouse model: Important role of metallothionein

(2015) Tingting Liang et al.   TOXICOLOGY LETTERS

Prevalence and Determinants of Metabolic Health in Subjects with Obesity in Chinese Population

(2015) Ruizhi Zheng et al.   International Journal of Environmental Research and Public Health

Sulforaphane reduction of testicular apoptotic cell death in diabetic mice is associated with the upregulation of Nrf2 expression and function

(2014) Yonggang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Zinc protects cyclophosphamide-induced testicular damage in rat: Involvement of metallothionein, tesmin and Nrf2

(2014) Krishna Prahlad Maremanda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Biological consequences of zinc deficiency in the pathomechanisms of selected diseases

(2014) Kamil Jurowski et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Zinc is essential for the transcription function of Nrf2 in human renal tubule cellsin vitroand mouse kidneyin vivounder the diabetic condition

(2014) Bing Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Anti-obesity and cardioprotective effects of cinnamic acid in high fat diet- induced obese rats

(2014) Kais Mnafgui et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Zinc rescue of Akt2 gene deletion-linked murine cardiac dysfunction and pathological changes is metallothionein-dependent

(2014) Weixia Sun et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Sulforaphane Attenuation of Type 2 Diabetes-Induced Aortic Damage Was Associated with the Upregulation of Nrf2 Expression and Function

(2014) Yonggang Wang et al.   Oxidative Medicine and Cellular Longevity

The role of the Nrf2/Keap1 pathway in obesity and metabolic syndrome

(2014) Zhiguo Zhang et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Protection by sulforaphane from type 1 diabetes-induced testicular apoptosis is associated with the up-regulation of Nrf2 expression and function

(2014) Xin Jiang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2

(2013) Xiao Miao et al.   Cardiovascular Diabetology

Marginal dietary zinc deficiency in vivo induces vascular smooth muscle cell apoptosis in large arteries

(2013) Keith Allen-Redpath et al.   CARDIOVASCULAR RESEARCH

Keap1 knockdown increases markers of metabolic syndrome after long-term high fat diet feeding

(2013) Vijay R. More et al.   FREE RADICAL BIOLOGY AND MEDICINE

Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2

(2013) Weixia Sun et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

(2013) Yang Bai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Zinc Deficiency Induces Vascular Pro-Inflammatory Parameters Associated with NF-κB and PPAR Signaling

(2013) Huiyun Shen et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Physical Activity and Cardiovascular Disease in African Americans in Atherosclerosis Risk in Communities

(2013) ELIZABETH J. BELL et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease

(2013) Dick de Zeeuw et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Role for Soluble ST2 in Vascular Remodeling Associated with Obesity in Rats

(2013) Ernesto Martínez-Martínez et al.   PLoS One

Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles

(2013) David Heber et al.   Food & Function

Zinc homeostasis in the metabolic syndrome and diabetes

(2013) Xiao Miao et al.   Frontiers of Medicine

Bardoxolone Brings Nrf2-Based Therapies to Light

(2012) Donna D. Zhang   ANTIOXIDANTS & REDOX SIGNALING

Heterogeneity in Obesity Status and Cardiovascular Risks in Multiethnic Asian Female Immigrants in South Korea

(2012) Seunghyun Yoo et al.   Asia-Pacific Journal of Public Health

Uncoupling Protein-2 Protects Endothelial Function in Diet-Induced Obese Mice

(2012) Xiao Yu Tian et al.   CIRCULATION RESEARCH

Enhanced Nrf2 Activity Worsens Insulin Resistance, Impairs Lipid Accumulation in Adipose Tissue, and Increases Hepatic Steatosis in Leptin-Deficient Mice

(2012) J. Xu et al.   DIABETES

Sulforaphane prevention of diabetes-induced aortic damage was associated with the up-regulation of Nrf2 and its down-stream antioxidants

(2012) Xiao Miao et al.   Nutrition & Metabolism

Diabetes-Induced Hepatic Pathogenic Damage, Inflammation, Oxidative Stress, and Insulin Resistance Was Exacerbated in Zinc Deficient Mouse Model

(2012) Chi Zhang et al.   PLoS One

Cardiovascular Risk Factors in an Eastern Caribbean Island: Prevalence of Non-communicable Chronic Diseases and Associated Lifestyle Risk Factors for Cardiovascular Morbidity and Mortality in the British Virgin Islands

(2012) J James et al.   WEST INDIAN MEDICAL JOURNAL

Marginal Zinc Deficiency Exacerbates Experimental Colitis Induced by Dextran Sulfate Sodium in Rats

(2011) Hitoshi Iwaya et al.   JOURNAL OF NUTRITION

Zinc deficiency exacerbates diabetic down-regulation of Akt expression and function in the testis: essential roles of PTEN, PTP1B and TRB3

(2011) Yuguang Zhao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Oxidative stress and inflammatory mediators contribute to endothelial dysfunction in high-fat diet-induced obesity in mice

(2010) Renata Kobayasi et al.   JOURNAL OF HYPERTENSION

Zinc deficiency decreased cell viability both in endothelial EA.hy926 cells and mouse aortic culture ex vivo and its implication for anti-atherosclerosis

(2009) Young-Eun Cho et al.   Nutrition Research and Practice

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Aorta protein networks in marginal and acute zinc deficiency

(2008) John H. Beattie et al.   PROTEOMICS