Sulforaphane Attenuation of Type 2 Diabetes-Induced Aortic Damage Was Associated with the Upregulation of Nrf2 Expression and Function

Anticancer Activity of a Broccoli Derivative, Sulforaphane, in Barrett Adenocarcinoma: Potential Use in Chemoprevention and as Adjuvant in Chemotherapy

(2014) Aamer Qazi et al.   Translational Oncology

Resveratrol and fish oil reduce catecholamine-induced mortality in obese rats: role of oxidative stress in the myocardium and aorta

(2013) Pricila R. M. Ávila et al.   BRITISH JOURNAL OF NUTRITION

Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2

(2013) Xiao Miao et al.   Cardiovascular Diabetology

A Novel Mechanism by Which SDF-1  Protects Cardiac Cells From Palmitate-Induced Endoplasmic Reticulum Stress and Apoptosis via CXCR7 and AMPK/p38 MAPK-Mediated Interleukin-6 Generation

(2013) Y. Zhao et al.   DIABETES

Earlier Onset of Complications in Youth With Type 2 Diabetes

(2013) A. B. Dart et al.   DIABETES CARE

Association of biomarkers of inflammation and oxidative stress with the risk of chronic kidney disease in Type 2 diabetes mellitus in North Indian population

(2013) Stuti Gupta et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Therapeutic Effect of MG132 on the Aortic Oxidative Damage and Inflammatory Response in OVE26 Type 1 Diabetic Mice

(2013) Xiao Miao et al.   Oxidative Medicine and Cellular Longevity

Strategies for preventing type 2 diabetes: an update for clinicians

(2013) Kaivan Khavandi et al.   Therapeutic Advances in Chronic Disease

Inflammation and Vascular Injury

(2012) Daniel I. Simon   CIRCULATION JOURNAL

Sulforaphane prevention of diabetes-induced aortic damage was associated with the up-regulation of Nrf2 and its down-stream antioxidants

(2012) Xiao Miao et al.   Nutrition & Metabolism

Phytochemical Activation of Nrf2 Protects Human Coronary Artery Endothelial Cells against an Oxidative Challenge

(2012) Elise L. Donovan et al.   Oxidative Medicine and Cellular Longevity

Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia

(2011) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications

(2011) Young-Sam Keum   Annals of the New York Academy of Sciences

Mechanism of the Nrf2/Keap1/ARE signaling system

(2011) V. O. Tkachev et al.   BIOCHEMISTRY-MOSCOW

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

(2011) P. Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nrf2 Activators as Attractive Therapeutics for Diabetic Nephropathy: FIG. 1.

(2011) Judy B. de Haan   DIABETES

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

(2011) Y. Tan et al.   DIABETES

Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress

(2011) Ya-Chen Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deficiency of CuZn Superoxide Dismutase Promotes Inflammation and Alters Medial Structure Following Vascular Injury

(2011) Norio Ishigami et al.   Journal of Atherosclerosis and Thrombosis

The influence of sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease

(2011) Paul C. Evans   EPMA Journal

New Perspectives on Diabetic Vascular Complications: The Loss of Endogenous Protective Factors Induced by Hyperglycemia

(2011) In-Kyung Jeong et al.   Diabetes & Metabolism Journal

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

(2010) Gerasimos P Sykiotis et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

(2010) T. Jiang et al.   DIABETES

Protective effect of sulforaphane against oxidative stress: Recent advances

(2010) Carlos Enrique Guerrero-Beltrán et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Coupling Vascular and Myocardial Inflammatory Injury into a Common Phenotype of Cardiovascular Dysfunction: Systemic Inflammation and Aging – A Mini-Review

(2010) Valentina O. Puntmann et al.   GERONTOLOGY

Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes

(2009) Alan R. Collins et al.   CIRCULATION RESEARCH

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

(2008) Xiaoqing He et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS