Article
Multidisciplinary Sciences
Carolina Parra, Francis C. Niestemski, Alex W. Contryman, Paula Giraldo-Gallo, Theodore H. Geballe, Ian R. Fisher, Hari C. Manoharan
Summary: Spatially resolved scanning tunneling spectroscopy measurements on the 3D superconductor BaPb1-xBixO3 reveal key signatures of emergent electronic granularity, previously only conjectured and observed in 2D thin-film systems. These signatures include emergent superconducting domains, finite energy gap, and enhanced spatial anticorrelation between pairing amplitude and gap magnitude near the superconductor-insulator transition. This suggests the presence of 2D superconducting behavior within a conventional 3D s-wave host, hinting at an unexplained interdimensional phenomenon.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemical Research Methods
Giulia Campostrini, Viviana Meraviglia, Elisa Giacomelli, Ruben W. J. van Helden, Loukia Yiangou, Richard P. Davis, Milena Bellin, Valeria V. Orlova, Christine L. Mummery
Summary: This protocol enables the generation of three principal cell types in the heart from hiPSCs to build 3D cardiac microtissues with specific functions. The differentiation, construction, and analysis steps are straightforward and convenient.
Article
Engineering, Biomedical
Ou Wang, Li Han, Haishuang Lin, Mingmei Tian, Shuyang Zhang, Bin Duan, Soonkyu Chung, Chi Zhang, Xiaojun Lian, Yong Wang, Yuguo Lei
Summary: Transplanting injectable microtissues of brown adipocytes can improve cell survival and effectively treat obesity and type 2 diabetes.
BIOACTIVE MATERIALS
(2023)
Review
Multidisciplinary Sciences
Susanne Reischauer, Bartholomaeus Pieber
Summary: Researchers have improved photocatalysts by adjusting the wavelength and intensity to control or change the selectivity of chemical reactions. In addition, recent efforts have focused on substituting strong reductants, such as elemental lithium and sodium, with light and technological advancements.
Article
Pediatrics
Megan H. Pesch, Mark R. Schleiss
Summary: This article reviews recent developments in the understanding of congenital cytomegalovirus (cCMV), including epidemiology and transmission, diagnostic strategies, newborn screening programs, therapeutics, and vaccine trials. It discusses how this knowledge informs the pathophysiology of cCMV and directs strategies for improving outcomes and quality of life for infected children. The article also provides an update on the epidemiology of cCMV in the United States, evolving understanding of maternal-fetal transmission, enhanced screening approaches, and recognition of neonatal and long-term sequelae. Finally, it reviews the current landscape of pediatric cCMV research and gives recommendations for future investigation.
Review
Immunology
Aicha Laghmouchi, Nuno A. G. Graca, Jan Voorberg
Summary: Immune thrombotic thrombocytopenic purpura (iTTP) is an autoimmune disorder characterized by the presence of autoantibodies targeting ADAMTS13, with genetic and environmental factors playing a role in its development. HLA-DRB1*11 and HLA-DRB1*08:03 have been identified as risk factors for iTTP in different populations. Infections with microorganisms may disrupt tolerance and lead to the induction of autoimmunity against ADAMTS13.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Arthur Colly, Christophe Marquette, Jean-Marc Frances, Edwin-Joffrey Courtial
Summary: Freeform three-dimensional (3D) printing technique is a promising field in additive manufacturing, allowing for the production of complex shapes with advanced materials. This article aims to address the lack of standardization in terminology and provide an overview of the application domains for freeform 3D printing.
Article
Engineering, Multidisciplinary
Yuanwei Lin, Yang Zhang, Yuqi Jin, Kaiyuan Guan, Qimin Ma, Yutong Cui, Bin Yang
Summary: A 3D PTV algorithm based on the MVEE and IEE is proposed. Different versions of this algorithm are proposed by incorporating the features of MVEE and Voronoi polyhedron. Among these versions, the Voronoi polyhedron feature expressed by IEE has the best performance, leading to a completely ellipsoid-based version named E-PTV. E-PTV is parameter-independent and optimally efficient, and it shows accuracy comparable to other 3D PTV algorithms. Combining E-PTV with the V3V system successfully reconstructs an actual 3D vortex ring flow, confirming the practicality of E-PTV.
Editorial Material
Chemistry, Physical
Line Naesborg, Bartholomaus Pieber, Oliver S. S. Wenger
Summary: This Special Collection focuses on photocatalytic synthesis and comprises a diverse range of original research contributions. It includes investigations on catalyst development, mechanisms, methodology advancements, and the utilization of enabling technologies, showcasing cutting-edge research in the field. Additionally, three reviews and a concept article explore and discuss emerging topics.
Review
Biotechnology & Applied Microbiology
Bali Pulendran, Prabhu S. Arunachalam, Derek T. O'Hagan
Summary: Adjuvants are vaccine components that enhance the immune response. Recent advances in understanding the molecular mechanisms and systems vaccinology have revitalized the science and development of novel adjuvants for use in vaccines against COVID-19 and future pandemics.
NATURE REVIEWS DRUG DISCOVERY
(2021)
Review
Microbiology
Brandon Sit, Bolutife Fakoya, Matthew K. Waldor
Summary: Cholera, caused by Vibrio cholerae, is a severe diarrheal disease that poses a significant public health threat in many parts of the world. Recent advancements in oral and nonoral cholera vaccine platforms have opened up new opportunities for vaccine design and implementation. As a preventable disease, cholera remains an important area for the development and application of cutting-edge technologies and platforms.
ANNUAL REVIEW OF MICROBIOLOGY
(2022)
Editorial Material
Pathology
Julia S. Lehman, Lori A. Erickson
Summary: This special issue of Human Pathology highlights the latest updates in dermatopathology, covering important topics in neoplastic, inflammatory, or special-site dermatopathology. It aims to help pathologists tackle these challenging areas in dermatopathology.
Review
Radiology, Nuclear Medicine & Medical Imaging
Laurent Dercle, Shawn Sun, Romain-David Seban, Ahmed Mekki, Roger Sun, Lambros Tselikas, Sophie Hans, Alice Bernard-Tessier, Fadila Mihoubi Bouvier, Nicolas Aide, Laetitia Vercellino, Alexia Rivas, Antoine Girard, Fatima-Zohra Mokrane, Guillaume Manson, Roch Houot, Egesta Lopci, Randy Yeh, Samy Ammari, Lawrence H. Schwartz
Summary: Criteria based on measurements of lesion diameter at CT have guided treatment with historical therapies due to the strong association between tumor size and survival. Clinical experience with immune checkpoint modulators shows that editing immune system function can be effective in various solid tumors. However, the emergence of novel immune-related phenomena challenges the association of tumor size with response or progression, presenting new demands for imaging to guide treatment decisions. Hence, further research on imaging techniques is crucial.
Review
Immunology
Rodolfo R. Favaro, Katherine Phillips, Romane Delaunay-Danguy, Kaja Ujcic, Udo R. Markert
Summary: Members of the innate immune system, specifically innate lymphoid cells (ILCs), play important roles in the uterine environment, supporting pregnancy and placental development. These cells demonstrate immune memory, allowing them to remember previously encountered antigens and mount enhanced responses. By studying ILCs, we can gain insights into the immunological mechanisms underlying female fertility/infertility, placental development, and distinct outcomes in second pregnancies.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Devi Jaganathan, Emanuela M. Bruscia, Benjamin T. Kopp
Summary: Cystic fibrosis is a disease caused by mutations in the CFTR gene, resulting in chronic inflammation and lung function decline. Macrophages play a crucial role in CF and the mutant CFTR affects phagocytosis, which is linked to disease progression. A better understanding of the interaction between CFTR and macrophages during phagosome formation could contribute to the development of new therapeutic strategies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)