Crucial Role of P2X7Receptor in Regulating Exocytosis of Single-Walled Carbon Nanotubes in Macrophages

Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate

(2015) Gregory Hook et al.   Frontiers in Neurology

Co-exposure of Carboxyl-Functionalized Single-Walled Carbon Nanotubes and 17α-Ethinylestradiol in Cultured Cells: Effects on Bioactivity and Cytotoxicity

(2014) Maoyong Song et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Lysophospholipids and ATP Mutually Suppress Maturation and Release of IL-1  in Mouse Microglial Cells Using a Rho-Dependent Pathway

(2014) T. Takenouchi et al.   JOURNAL OF IMMUNOLOGY

Purinergic signaling via P2X7 receptor mediates IL-1β production in Kupffer cells exposed to silica nanoparticle

(2014) Shuji Kojima et al.   TOXICOLOGY

A differential role of macrophage TRPM2 channels in Ca2+ signaling and cell death in early responses to H2O2

(2013) Jie Zou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Uptake and intracellular distribution of collagen-functionalized single-walled carbon nanotubes

(2013) Hongli Mao et al.   BIOMATERIALS

Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor

(2013) Sonia Guha et al.   FASEB JOURNAL

Lysosomal exocytosis and caspase-8-mediated apoptosis in UVA-irradiated keratinocytes

(2013) Hanna Appelqvist et al.   JOURNAL OF CELL SCIENCE

Physiological Roles and Potential Therapeutic Applications of the P2X7 Receptor in Inflammation and Pain

(2013) Luiz Alves et al.   MOLECULES

Characterization of P2X7R and Its Function in the Macrophages of ayu, Plecoglossus altivelis

(2013) Yu-Qing He et al.   PLoS One

Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages

(2013) Bin Wan et al.   TOXICOLOGY LETTERS

The Regulation of Calcium Homeostasis in T Lymphocytes

(2013) Gergely Toldi   Frontiers in Immunology

P2X7 receptor regulation of non-classical secretion from immune effector cells

(2012) George R. Dubyak   CELLULAR MICROBIOLOGY

P2X7 Receptors: Channels, Pores and More

(2012) C. Volonte et al.   CNS & Neurological Disorders-Drug Targets

Extracellular ATP Exerts Opposite Effects on Activated and Regulatory CD4+ T Cells via Purinergic P2 Receptor Activation

(2012) S. Trabanelli et al.   JOURNAL OF IMMUNOLOGY

Exocytosis of peptide functionalized gold nanoparticles in endothelial cells

(2012) Dorota Bartczak et al.   Nanoscale

Cell cooperation and role of the P2X7receptor in pulmonary inflammation induced by nanoparticles

(2012) Samir Dekali et al.   Nanotoxicology

Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis

(2012) Brian D Gulbransen et al.   NATURE MEDICINE

Activation of P2X7 Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection

(2012) Benjamin H. Lee et al.   PLoS One

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

(2012) N Riteau et al.   Cell Death & Disease

Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

(2011) Jaana Palomäki et al.   ACS Nano

Lysosomal membrane destabilization induced by high accumulation of single-walled carbon nanohorns in murine macrophage RAW 264.7

(2011) Yoshio Tahara et al.   BIOMATERIALS

Cellular uptake mechanisms of functionalised multi-walled carbon nanotubes by 3D electron tomography imaging

(2011) Khuloud T. Al-Jamal et al.   Nanoscale

In vitrotoxicity of acid-functionalized single-walled carbon nanotubes: Effects on murine macrophages and gene expression profiling

(2011) Ping-Xuan Dong et al.   Nanotoxicology

Label-free imaging of semiconducting and metallic carbon nanotubes in cells and mice using transient absorption microscopy

(2011) Ling Tong et al.   Nature Nanotechnology

Single wall carbon nanotubes enter cells by endocytosis and not membrane penetration

(2011) Peter N Yaron et al.   JOURNAL OF NANOBIOTECHNOLOGY

Endo- and Exocytosis of Zwitterionic Quantum Dot Nanoparticles by Live HeLa Cells

(2010) Xiue Jiang et al.   ACS Nano

Extracellular ATP Is a Danger Signal Activating P2X7Receptor in Lung Inflammation and Fibrosis

(2010) Nicolas Riteau et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

P2X7 Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages

(2010) M. P. Lees et al.   JOURNAL OF IMMUNOLOGY

Pathways for Cytokine Secretion

(2010) Amanda C. Stanley et al.   PHYSIOLOGY

Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles

(2009) Hong Jin et al.   ACS Nano

Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-Directed Carbon Nanotube-Based Drug Delivery

(2009) Ashwin A. Bhirde et al.   ACS Nano

Gel Electrophoresis Method to Measure the Concentration of Single-Walled Carbon Nanotubes Extracted from Biological Tissue

(2009) Ruhung Wang et al.   ANALYTICAL CHEMISTRY

Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles

(2009) Hae Yun Nam et al.   JOURNAL OF CONTROLLED RELEASE

The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells

(2009) T. Takenouchi et al.   JOURNAL OF IMMUNOLOGY

Modulation of P2X7 purinergic receptor in macrophages by Leishmania amazonensis and its role in parasite elimination

(2009) Suzana Passos Chaves et al.   MICROBES AND INFECTION

Lysosomal cytotoxicity of carbon nanoparticles in cells of the molluscan immune system: An in vitro study

(2009) Michael N. Moore et al.   Nanotoxicology

P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways

(2009) Yan Qu et al.   Purinergic Signalling

Cathepsin D Is the Main Lysosomal Enzyme Involved in the Degradation of α-Synuclein and Generation of Its Carboxy-Terminally Truncated Species†

(2008) Daniel Sevlever et al.   BIOCHEMISTRY

Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts

(2008) S. Armstrong et al.   JOURNAL OF CELL SCIENCE

Smooth muscle cell calcium activation mechanisms

(2008) Michael J. Berridge   JOURNAL OF PHYSIOLOGY-LONDON

Functionalized Single-Walled Carbon Nanotubes as Rationally Designed Vehicles for Tumor-Targeted Drug Delivery

(2008) Jingyi Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Biodistribution of Oligonucleotide-Functionalized, Tumor-Targetable Carbon Nanotubes

(2008) Carlos H. Villa et al.   NANO LETTERS

Single-Particle Tracking of Endocytosis and Exocytosis of Single-Walled Carbon Nanotubes in NIH-3T3 Cells

(2008) Hong Jin et al.   NANO LETTERS