Microenvironment-Responsive Three-Pronged Approach Breaking Traditional Chemotherapy to Target Cancer Stem Cells for Synergistic Inoperable Large Tumor Therapy

Size Changeable Nanocarriers with Nuclear Targeting for Effectively Overcoming Multidrug Resistance in Cancer Therapy

(2015) Xing Guo et al.   ADVANCED MATERIALS

Smart Albumin-Biomineralized Nanocomposites for Multimodal Imaging and Photothermal Tumor Ablation

(2015) Yong Wang et al.   ADVANCED MATERIALS

Enhanced retention and anti-tumor efficacy of liposomes by changing their cellular uptake and pharmacokinetics behavior

(2015) Yan Li et al.   BIOMATERIALS

Intracellular autofluorescence: a biomarker for epithelial cancer stem cells

(2014) Irene Miranda-Lorenzo et al.   NATURE METHODS

High selectivity imaging of nitroreductase using a near-infrared fluorescence probe in hypoxic tumor

(2013) Kehua Xu et al.   CHEMICAL COMMUNICATIONS

HPMA copolymer-based combination therapy toxic to both prostate cancer stem/progenitor cells and differentiated cells induces durable anti-tumor effects

(2013) Yan Zhou et al.   JOURNAL OF CONTROLLED RELEASE

Self-Assembled Plasmonic Vesicles of SERS-Encoded Amphiphilic Gold Nanoparticles for Cancer Cell Targeting and Traceable Intracellular Drug Delivery

(2012) Jibin Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Shear-stress sensitive lenticular vesicles for targeted drug delivery

(2012) Margaret N. Holme et al.   Nature Nanotechnology

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

(2012) S. J. Conley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes

(2011) Niravkumar R. Patel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

(2011) Hasan Korkaya et al.   JOURNAL OF CLINICAL INVESTIGATION

Tailor-Made Dual pH-Sensitive Polymer–Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery

(2011) Jin-Zhi Du et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The cancer stem cell: premises, promises and challenges

(2011) Hans Clevers   NATURE MEDICINE

A New Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell

(2011) Lei Cui et al.   ORGANIC LETTERS

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery

(2010) Youqing Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Charge-Reversal Drug Conjugate for Targeted Cancer Cell Nuclear Drug Delivery

(2009) Zhuxian Zhou et al.   ADVANCED FUNCTIONAL MATERIALS

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

(2009) Emmanuelle Charafe-Jauffret et al.   CANCER RESEARCH

Breast cancer chemoresistance: Emerging importance of cancer stem cells

(2009) Suebwong Chuthapisith et al.   SURGICAL ONCOLOGY-OXFORD