Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer’s disease
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Title
Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer’s disease
Authors
Keywords
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Journal
Science Translational Medicine
Volume 8, Issue 332, Pages 332ra44-332ra44
Publisher
American Association for the Advancement of Science (AAAS)
Online
2016-03-31
DOI
10.1126/scitranslmed.aad3650
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Note: Only part of the references are listed.- Overexpression of Heparanase Lowers the Amyloid Burden in Amyloid-β Precursor Protein Transgenic Mice
- (2014) Charlotte B. Jendresen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deficiency in LRP6-Mediated Wnt Signaling Contributes to Synaptic Abnormalities and Amyloid Pathology in Alzheimer’s Disease
- (2014) Chia-Chen Liu et al. NEURON
- ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?
- (2014) Takahisa Kanekiyo et al. NEURON
- Serial propagation of distinct strains of A prions from Alzheimer's disease patients
- (2014) J. C. Watts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- β-Amyloid is transmitted via neuronal connections along axonal membranes
- (2013) Ha-Lim Song et al. ANNALS OF NEUROLOGY
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Non-toxic amyloid beta formed in the presence of glypican-1 or its deaminatively generated heparan sulfate degradation products
- (2013) Fang Cheng et al. GLYCOBIOLOGY
- Neuronal Clearance of Amyloid- by Endocytic Receptor LRP1
- (2013) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
- (2013) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
- (2013) L. Mucke et al. Cold Spring Harbor Perspectives in Medicine
- Neurovascular Dysfunction and Faulty Amyloid -Peptide Clearance in Alzheimer Disease
- (2013) A. P. Sagare et al. Cold Spring Harbor Perspectives in Medicine
- Proteolytic Degradation of Amyloid -Protein
- (2013) T. Saido et al. Cold Spring Harbor Perspectives in Medicine
- A Mass Spectrometric Approach for Characterization of Amyloid-β Aggregates and Identification of Their Post-Translational Modifications
- (2012) William M. Tay et al. BIOCHEMISTRY
- Alzheimer Mechanisms and Therapeutic Strategies
- (2012) Yadong Huang et al. CELL
- Differential Regulation of Amyloid-β Endocytic Trafficking and Lysosomal Degradation by Apolipoprotein E Isoforms
- (2012) Jie Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology
- (2012) Pritam Das et al. Molecular Neurodegeneration
- Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody
- (2012) Katherine L Youmans et al. Molecular Neurodegeneration
- Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate
- (2012) F. Irie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines
- (2012) Jose Miguel Rubio-Perez et al. TheScientificWorldJOURNAL
- Changes in Brain β-Amyloid Deposition and Aquaporin 4 Levels in Response to AlteredAgrinExpression in Mice
- (2011) Steven M. Rauch et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid- Uptake
- (2011) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β42 alters apolipoprotein E solubility in brains of mice with five familial AD mutations
- (2011) Katherine Lynn Youmans et al. JOURNAL OF NEUROSCIENCE METHODS
- Neuronal activity regulates the regional vulnerability to amyloid-β deposition
- (2011) Adam W Bero et al. NATURE NEUROSCIENCE
- Serotonin signaling is associated with lower amyloid- levels and plaques in transgenic mice and humans
- (2011) J. R. Cirrito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- Heparan Sulfate Proteoglycans
- (2011) S. Sarrazin et al. Cold Spring Harbor Perspectives in Biology
- Heparan sulfate mediates amyloid-beta internalization and cytotoxicity
- (2010) Elina Sandwall et al. GLYCOBIOLOGY
- IFN- Promotes Complement Expression and Attenuates Amyloid Plaque Deposition in Amyloid Precursor Protein Transgenic Mice
- (2010) P. Chakrabarty et al. JOURNAL OF IMMUNOLOGY
- Limited expression of heparan sulphate proteoglycans associated with Aβ deposits in the APPswe/PS1dE9 mouse model for Alzheimer's disease
- (2010) N. M. Timmer et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Decreased Clearance of CNS -Amyloid in Alzheimer's Disease
- (2010) K. G. Mawuenyega et al. SCIENCE
- A Specific Enzyme-Linked Immunosorbent Assay for Measuring β-Amyloid Protein Oligomers in Human Plasma and Brain Tissue of Patients With Alzheimer Disease
- (2009) Weiming Xia et al. ARCHIVES OF NEUROLOGY
- Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain
- (2009) Karrie E Grear et al. Molecular Neurodegeneration
- Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
- (2009) Guojun Bu NATURE REVIEWS NEUROSCIENCE
- Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide
- (2009) X. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
- (2008) Dennis J. Selkoe BEHAVIOURAL BRAIN RESEARCH
- SYMPOSIUM: Clearance of Aβ from the Brain in Alzheimer's Disease: Aβ-Degrading Enzymes in Alzheimer's Disease
- (2008) James Scott Miners et al. BRAIN PATHOLOGY
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