Cardiac BIN1 (cBIN1) is a regulator of cardiac contractile function and an emerging biomarker of heart muscle health

BIN1 regulates dynamic t-tubule membrane

(2016) Ying Fu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)–Organized DyadsCLINICAL PERSPECTIVE

(2016) Ying Fu et al.   CIRCULATION

Mitochondrial Ca2+ uptake in skeletal muscle health and disease

(2016) Jingsong Zhou et al.   Science China-Life Sciences

Ca2+ microdomains organized by junctophilins

(2015) Hiroshi Takeshima et al.   CELL CALCIUM

Cardiac-Specific Disruption of Bin1 in Mice Enables a Model of Stress- and Age-Associated Dilated Cardiomyopathy

(2015) Lisa D. Laury-Kleintop et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Dependence of Cardiac Transverse Tubules on the BAR Domain Protein Amphiphysin II (BIN-1)

(2014) Jessica L. Caldwell et al.   CIRCULATION RESEARCH

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

(2014) TingTing Hong et al.   NATURE MEDICINE

Canonical transient receptor potential 4 and its small molecule modulators

(2014) Jie Fu et al.   Science China-Life Sciences

Ultrastructural uncoupling between T-tubules and sarcoplasmic reticulum in human heart failure

(2013) H.-B. Zhang et al.   CARDIOVASCULAR RESEARCH

Critical roles of junctophilin-2 in T-tubule and excitation–contraction coupling maturation during postnatal development

(2013) Biyi Chen et al.   CARDIOVASCULAR RESEARCH

Emerging mechanisms of T-tubule remodelling in heart failure

(2013) Ang Guo et al.   CARDIOVASCULAR RESEARCH

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development

(2013) Julia O. Reynolds et al.   CARDIOVASCULAR RESEARCH

Reversibility of T-tubule remodelling in heart failure: mechanical load as a dynamic regulator of the T-tubules

(2013) Michael Ibrahim et al.   CARDIOVASCULAR RESEARCH

The transverse-axial tubular system of cardiomyocytes

(2013) C. Ferrantini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ultrastructural remodelling of Ca2+ signalling apparatus in failing heart cells

(2012) Hao-Di Wu et al.   CARDIOVASCULAR RESEARCH

Plasticity of Surface Structures and β 2 -Adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure

(2012) Alexander R. Lyon et al.   Circulation-Heart Failure

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy

(2012) Ting-Ting Hong et al.   HEART RHYTHM

Disrupted Junctional Membrane Complexes and Hyperactive Ryanodine Receptors After Acute Junctophilin Knockdown in Mice

(2011) Ralph J. van Oort et al.   CIRCULATION

Let's go bananas: revisiting the endocytic BAR code

(2011) Britta Qualmann et al.   EMBO JOURNAL

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes

(2011) Ting-Ting Hong et al.   HEART RHYTHM

The structure and function of cardiac t-tubules in health and disease

(2011) M. Ibrahim et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis

(2011) Marcus J. Taylor et al.   PLOS BIOLOGY

Heart Disease and Stroke Statistics—2011 Update

(2010) Véronique L. Roger et al.   CIRCULATION

T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure

(2010) Sheng Wei et al.   CIRCULATION RESEARCH

There Goes the Neighborhood: Pathological Alterations in T-Tubule Morphology and Consequences for Cardiomyocyte Handling

(2010) William E. Louch et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Epidemiology and risk profile of heart failure

(2010) Anh L. Bui et al.   Nature Reviews Cardiology

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

(2010) Ting-Ting Hong et al.   PLOS BIOLOGY

The BAR Domain Superfamily: Membrane-Molding Macromolecules

(2009) Adam Frost et al.   CELL

Heart Disease and Stroke Statistics—2010 Update

(2009) et al.   CIRCULATION

 -Adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel

(2009) P. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart

(2009) A. R. Lyon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA