Emerging mechanisms of T-tubule remodelling in heart failure

Ultrastructural remodelling of Ca2+ signalling apparatus in failing heart cells

(2012) Hao-Di Wu et al.   CARDIOVASCULAR RESEARCH

Subcellular Structures and Function of Myocytes Impaired During Heart Failure Are Restored by Cardiac Resynchronization Therapy

(2012) Frank B. Sachse et al.   CIRCULATION RESEARCH

Mir-24 Regulates Junctophilin-2 Expression in Cardiomyocytes

(2012) Ming Xu et al.   CIRCULATION RESEARCH

Stimulated Emission Depletion Live-Cell Super-Resolution Imaging Shows Proliferative Remodeling of T-Tubule Membrane Structures After Myocardial Infarction

(2012) Eva Wagner et al.   CIRCULATION RESEARCH

Plasticity of Surface Structures and β 2 -Adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure

(2012) Alexander R. Lyon et al.   Circulation-Heart Failure

Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca2+-induced Ca2+release in a rodent model of heart failure

(2012) Michael Ibrahim et al.   EUROPEAN JOURNAL OF HEART FAILURE

β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction

(2012) Biyi Chen et al.   FASEB JOURNAL

A critical role for Telethonin in regulating t-tubule structure and function in the mammalian heart

(2012) M. Ibrahim et al.   HUMAN MOLECULAR GENETICS

Spatial variability in T-tubule and electrical remodeling of left ventricular epicardium in mouse hearts with transgenic Gαq overexpression-induced pathological hypertrophy

(2012) Wen Tao et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout

(2012) F. Swift et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Action potential propagation in transverse-axial tubular system is impaired in heart failure

(2012) L. Sacconi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical modulation of the transverse tubular system of ventricular cardiomyocytes

(2012) Thomas G. McNary et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Transverse tubules are a common feature in large mammalian atrial myocytes including human

(2011) M. A. Richards et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Strain Transfer in Ventricular Cardiomyocytes to Their Transverse Tubular System Revealed by Scanning Confocal Microscopy

(2011) Thomas G. McNary et al.   BIOPHYSICAL JOURNAL

Disrupted Junctional Membrane Complexes and Hyperactive Ryanodine Receptors After Acute Junctophilin Knockdown in Mice

(2011) Ralph J. van Oort et al.   CIRCULATION

Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy and Abnormal Intracellular Calcium-Handling

(2011) Andrew P. Landstrom et al.   Circulation-Heart Failure

Sildenafil Prevents and Reverses Transverse-Tubule Remodeling and Ca 2+ Handling Dysfunction in Right Ventricle Failure Induced by Pulmonary Artery Hypertension

(2011) Yu-Ping Xie et al.   HYPERTENSION

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

(2011) Charlotte Fugier et al.   NATURE MEDICINE

Changes in the Organization of Excitation-Contraction Coupling Structures in Failing Human Heart

(2011) David J. Crossman et al.   PLoS One

PI3Ks Maintain the Structural Integrity of T-Tubules in Cardiac Myocytes

(2011) Chia-Yen C. Wu et al.   PLoS One

The structure and function of cardiac t-tubules in health and disease

(2011) M. Ibrahim et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure

(2010) Sheng Wei et al.   CIRCULATION RESEARCH

Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface

(2010) Michael Ibrahim et al.   FASEB JOURNAL

There Goes the Neighborhood: Pathological Alterations in T-Tubule Morphology and Consequences for Cardiomyocyte Handling

(2010) William E. Louch et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts

(2010) Ole J. Kemi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

(2010) Ting-Ting Hong et al.   PLOS BIOLOGY

Ultrastructural and Functional Remodeling of the Coupling Between Ca 2+ Influx and Sarcoplasmic Reticulum Ca 2+ Release in Right Atrial Myocytes From Experimental Persistent Atrial Fibrillation

(2009) Ilse Lenaerts et al.   CIRCULATION RESEARCH

Ca 2+ Signaling Domains Responsible For Cardiac Hypertrophy and Arrhythmias

(2009) Steven R. Houser   CIRCULATION RESEARCH

Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca 2+ Control, and SR Ca 2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy

(2009) Tomas O. Stølen et al.   CIRCULATION RESEARCH

Characterization of an Extensive Transverse Tubular Network in Sheep Atrial Myocytes and its Depletion in Heart Failure

(2009) Katharine M. Dibb et al.   Circulation-Heart Failure

The role of mammalian cardiac t-tubules in excitation-contraction coupling: experimental and computational approaches

(2009) Clive H. Orchard et al.   EXPERIMENTAL PHYSIOLOGY

Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere–membrane interaction, not sarcomere assembly

(2009) Ruilin Zhang et al.   HUMAN MOLECULAR GENETICS

Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart

(2009) A. R. Lyon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Features of the Rabbit Transverse Tubular System Revealed by Quantitative Analysis of Three-Dimensional Reconstructions from Confocal Images

(2008) Eleonora Savio-Galimberti et al.   BIOPHYSICAL JOURNAL

Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase  2-isoform in heart failure

(2008) F. Swift et al.   CARDIOVASCULAR RESEARCH

Calcium Sparks

(2008) Heping Cheng et al.   PHYSIOLOGICAL REVIEWS

Remodeling of T-Tubules and Reduced Synchrony of Ca 2+ Release in Myocytes From Chronically Ischemic Myocardium

(2007) Frank R. Heinzel et al.   CIRCULATION RESEARCH

Modelling the cardiac transverse-axial tubular system

(2007) M. Pásek et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY