Cardiac-Specific Disruption of Bin1 in Mice Enables a Model of Stress- and Age-Associated Dilated Cardiomyopathy

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

(2014) TingTing Hong et al.   NATURE MEDICINE

The myotubularin–amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

(2013) Barbara Royer et al.   EMBO REPORTS

Altered Splicing of the BIN1 Muscle-Specific Exon in Humans and Dogs with Highly Progressive Centronuclear Myopathy

(2013) Johann Böhm et al.   PLoS Genetics

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy

(2012) Ting-Ting Hong et al.   HEART RHYTHM

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes

(2011) Ting-Ting Hong et al.   HEART RHYTHM

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

(2011) Charlotte Fugier et al.   NATURE MEDICINE

Defects in amphiphysin 2 (BIN1) and triads in several forms of centronuclear myopathies

(2010) Anne Toussaint et al.   ACTA NEUROPATHOLOGICA

Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease

(2010) Lesley Jones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure

(2010) Sheng Wei et al.   CIRCULATION RESEARCH

Investigation of 15 of the top candidate genes for late-onset Alzheimer’s disease

(2010) Olivia Belbin et al.   HUMAN GENETICS

Alzheimer's disease genetics: current knowledge and future challenges

(2010) Paul Hollingworth et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

There Goes the Neighborhood: Pathological Alterations in T-Tubule Morphology and Consequences for Cardiomyocyte Handling

(2010) William E. Louch et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy

(2010) Xiongwen Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy

(2009) Melissa Swinnen et al.   CIRCULATION

Caveolinopathies: from the biology of caveolin-3 to human diseases

(2009) Elisabetta Gazzerro et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The role of mammalian cardiac t-tubules in excitation-contraction coupling: experimental and computational approaches

(2009) Clive H. Orchard et al.   EXPERIMENTAL PHYSIOLOGY

Bin1 Src Homology 3 Domain Acts as a Scaffold for Myofiber Sarcomere Assembly

(2009) Pasan Fernando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis

(2009) Beata Pyrzynska et al.   Molecular Oncology

Dilated Cardiomyopathy with Increased SR Ca2+ Loading Preceded by a Hypercontractile State and Diastolic Failure in the α1CTG Mouse

(2009) Su Wang et al.   PLoS One

Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7

(2008) Narendra Wajapeyee et al.   CELL

Ca 2+ Influx Through T- and L-Type Ca 2+ Channels Have Different Effects on Myocyte Contractility and Induce Unique Cardiac Phenotypes

(2008) Naser Jaleel et al.   CIRCULATION RESEARCH