Dynamic modulation of innate immunity programming and memory

Alteration of Lysosome Fusion and Low-grade Inflammation Mediated by Super-low-dose Endotoxin

(2015) Bianca Baker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

(2015) Xiaodi Su et al.   NATURE IMMUNOLOGY

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

(2015) Geming Lu et al.   Nature Communications

Super-low Dose Endotoxin Pre-conditioning Exacerbates Sepsis Mortality

(2015) Keqiang Chen et al.   EBioMedicine

Trehalose-Mediated Autophagy Impairs the Anti-Viral Function of Human Primary Airway Epithelial Cells

(2015) Qun Wu et al.   PLoS One

Dynamic Modulation of Innate Immune Response by Varying Dosages of Lipopolysaccharide (LPS) in Human Monocytic Cells

(2014) Matthew C. Morris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular and Cellular Mechanisms Responsible for Cellular Stress and Low-grade Inflammation Induced by a Super-low Dose of Endotoxin

(2014) Bianca Baker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Pre-treatment with low-dose endotoxin prolongs survival from experimental lethal endotoxic shock: Benefit for lethal peritonitis by Escherichia coli

(2013) Konstantinos Kopanakis et al.   CYTOKINE

Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

(2013) Yu Qiao et al.   IMMUNITY

Autophagy proteins regulate ERK phosphorylation

(2013) Nuria Martinez-Lopez et al.   Nature Communications

Molecular Mechanisms Responsible for the Reduced Expression of Cholesterol Transporters From Macrophages by Low-Dose Endotoxin

(2012) Urmila Maitra et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells

(2012) Tian Hong et al.   BMC Systems Biology

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Molecular Mechanism Responsible for the Priming of Macrophage Activation

(2012) Hui Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanisms Responsible for the Selective and Low-Grade Induction of Proinflammatory Mediators in Murine Macrophages by Lipopolysaccharide

(2012) U. Maitra et al.   JOURNAL OF IMMUNOLOGY

Network Topologies and Dynamics Leading to Endotoxin Tolerance and Priming in Innate Immune Cells

(2012) Yan Fu et al.   PLoS Computational Biology

Molecular Mechanisms and Pathological Consequences of Endotoxin Tolerance and Priming

(2011) Matthew Morris et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Low-Dose Endotoxin Induces Inflammation by Selectively Removing Nuclear Receptors and Activating CCAAT/Enhancer-Binding Protein δ

(2011) Urmila Maitra et al.   JOURNAL OF IMMUNOLOGY

A Mathematical Model for the Reciprocal Differentiation of T Helper 17 Cells and Induced Regulatory T Cells

(2011) Tian Hong et al.   PLoS Computational Biology

Nuclear Receptors and Inflammation Control: Molecular Mechanisms and Pathophysiological Relevance

(2010) Wendy Huang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotein Cooperatively Activate Macrophages via Nuclear Factor κB and Activator Protein-1

(2010) Philipp Wiesner et al.   CIRCULATION RESEARCH

The NF-κB Factor RelB and Histone H3 Lysine Methyltransferase G9a Directly Interact to Generate Epigenetic Silencing in Endotoxin Tolerance

(2009) Xiaoping Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-β-dependent pathways and increases expression of negative regulators of TLR signaling

(2009) Wenji Piao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

RelB Sustains I B  Expression during Endotoxin Tolerance

(2008) X. Chen et al.   Clinical and Vaccine Immunology

Lipopolysaccharide associates with pro-atherogenic lipoproteins in periodontitis patients

(2008) K.A. Elisa Kallio et al.   Innate Immunity

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark