Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

From Chemical Mutagenesis to Post-Expression Mutagenesis: A 50 Year Odyssey

(2016) Tom H. Wright et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pinpointing RNA-Protein Cross-Links with Site-Specific Stable Isotope-Labeled Oligonucleotides

(2015) Victor S. Lelyveld et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog

(2015) Daniel T Rogerson et al.   Nature Chemical Biology

Identification of protein complexes that bind to histone H3 combinatorial modifications using super-SILAC and weighted correlation network analysis

(2015) Natalia Kunowska et al.   NUCLEIC ACIDS RESEARCH

BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase

(2015) Abid Khan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gel-aided sample preparation (GASP)-A simplified method for gel-assisted proteomic sample generation from protein extracts and intact cells

(2015) Roman Fischer et al.   PROTEOMICS

Designing logical codon reassignment – Expanding the chemistry in biology

(2015) Anaëlle Dumas et al.   Chemical Science

Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation

(2015) Lukas Lercher et al.   Nature Communications

Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities

(2015) Masaki Kurogochi et al.   PLoS One

Analysis of Phosphorylation-Dependent Protein–Protein Interactions of Histone H3

(2014) Rebecca Klingberg et al.   ACS Chemical Biology

Novel LC-MS2 Product Dependent Parallel Data Acquisition Function and Data Analysis Workflow for Sequencing and Identification of Intact Glycopeptides

(2014) Sz-Wei Wu et al.   ANALYTICAL CHEMISTRY

Expanding and Reprogramming the Genetic Code of Cells and Animals

(2014) Jason W. Chin   Annual Review of Biochemistry

Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation

(2014) Stéphan Hardivillé et al.   Cell Metabolism

Recent extensions to native chemical ligation for the chemical synthesis of peptides and proteins

(2014) Lara R Malins et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The Emerging Link betweenO-GlcNAc and Alzheimer Disease

(2014) Yanping Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Site-Specific Thermodynamic Stability and Unfolding of a de Novo Designed Protein Structural Motif Mapped by 13C Isotopically Edited IR Spectroscopy

(2014) Ginka S. Kubelka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity

(2014) K. Phin Chooi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Redundant Mechanisms to Form Silent Chromatin at Pericentromeric Regions Rely on BEND3 and DNA Methylation

(2014) Nehmé Saksouk et al.   MOLECULAR CELL

Radical reactions of borohydrides

(2014) Takuji Kawamoto et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Selective chemical protein modification

(2014) Christopher D. Spicer et al.   Nature Communications

Realizing the promise of chemical glycobiology

(2013) Lai-Xi Wang et al.   Chemical Science

Conversion of Cysteine into Dehydroalanine Enables Access to Synthetic Histones Bearing Diverse Post-Translational Modifications

(2012) Justin M. Chalker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biased Signaling Pathways in  2-Adrenergic Receptor Characterized by 19F-NMR

(2012) J. J. Liu et al.   SCIENCE

A “Tag-and-Modify” Approach to Site-Selective Protein Modification

(2011) Justin M. Chalker et al.   ACCOUNTS OF CHEMICAL RESEARCH

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Methods for converting cysteine to dehydroalanine on peptides and proteins

(2011) Justin M. Chalker et al.   Chemical Science

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

(2010) Till Bartke et al.   CELL

Chemical mutagenesis: selective post-expression interconversion of protein amino acid residues

(2010) Justin M Chalker et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Lacticin 481 Synthetase as a General Serine/Threonine Kinase

(2009) Young Ok You et al.   ACS Chemical Biology

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Critical Examination of Escherichia coli Esterase Activity

(2009) Alicja K. Antonczak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetically EncodingNϵ-Methyl-l-lysine in Recombinant Histones

(2009) Duy P. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

BEN: a novel domain in chromatin factors and DNA viral proteins

(2008) Saraswathi Abhiman et al.   BIOINFORMATICS

Glycoprotein Synthesis: An Update

(2008) David P. Gamblin et al.   CHEMICAL REVIEWS

Molecular mechanisms of O-GlcNAcylation

(2008) Ramon Hurtado-Guerrero et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins

(2008) Gonçalo J. L. Bernardes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY