Perspectives for treating Alzheimer's disease: a review on promising pharmacological substances

Vitamin E, Memantine, and Alzheimer Disease

(2014) Denis A. Evans et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence

(2013) Jessica Freiherr et al.   CNS DRUGS

A Review: Treatment of Alzheimer’s Disease Discovered in Repurposed Agents

(2013) Brian S. Appleby et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Potential novel targets for Alzheimer pharmacotherapy: II. Update on secretase inhibitors and related approaches

(2013) J. A. Mikulca et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study

(2013) Y. Freund Levi et al.   JOURNAL OF INTERNAL MEDICINE

Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease

(2013) Eduardo Luis Konrath et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

(2013) Panayiota Papadopoulos et al.   PLoS One

Is There a Causal Link between Inflammation and Dementia?

(2013) Ana-Maria Enciu et al.   Biomed Research International

Phosphodiesterases as Therapeutic Targets for Alzheimer's Disease

(2012) Ana García-Osta et al.   ACS Chemical Neuroscience

Deregulated Cdk5 Activity Is Involved in Inducing Alzheimer’s Disease

(2012) Varsha Shukla et al.   ARCHIVES OF MEDICAL RESEARCH

Tamibarotene: A Candidate Retinoid Drug for Alzheimer’s Disease

(2012) Hiroshi Fukasawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Hormone therapy, dementia, and cognition: the Women's Health Initiative 10 years on

(2012) P. M. Maki et al.   CLIMACTERIC

Cotinine: A Potential New Therapeutic Agent against Alzheimer's disease

(2012) Valentina Echeverria et al.   CNS Neuroscience & Therapeutics

Insulin: An Emerging Treatment for Alzheimer’s Disease Dementia?

(2012) Jill K. Morris et al.   Current Neurology and Neuroscience Reports

Natural products as a rich source of tau-targeting drugs for Alzheimer’s disease

(2012) Laurent Calcul et al.   Future Medicinal Chemistry

Neurodegeneration, β-amyloid and mood disorders: state of the art and future perspectives

(2012) Armando Piccinni et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Cochrane review on ‘Statins for the treatment of dementia’

(2012) Bernadette McGuinness et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology

(2012) Timothy Revett et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Integrating Cytosolic Phospholipase A2 with Oxidative/Nitrosative Signaling Pathways in Neurons: A Novel Therapeutic Strategy for AD

(2012) Grace Y. Sun et al.   MOLECULAR NEUROBIOLOGY

Terpenoids as Potential Anti-Alzheimer’s Disease Therapeutics

(2012) Ki-Yeol Yoo et al.   MOLECULES

Antioxidant Therapies for Alzheimer's Disease

(2012) Ye Feng et al.   Oxidative Medicine and Cellular Longevity

Statins in the prevention of dementia and Alzheimer's disease: A meta-analysis of observational studies and an assessment of confounding

(2012) William B. Wong et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Antihypertensives for combating dementia? A perspective on candidate molecular mechanisms and population-based prevention

(2012) M Valenzuela et al.   Translational Psychiatry

ACS Chemical Neuroscience Molecule Spotlight on ELND006: Another γ-Secretase Inhibitor Fails in the Clinic

(2011) Corey R. Hopkins   ACS Chemical Neuroscience

Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine

(2011) Thimmappa S. Anekonda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Clinical Efficacy of Aniracetam, Either as Monotherapy or Combined with Cholinesterase Inhibitors, in Patients with Cognitive Impairment: A Comparative Open Study*

(2011) Chrysi C. Koliaki et al.   CNS Neuroscience & Therapeutics

Developing β-secretase inhibitors for treatment of Alzheimer’s disease

(2011) Arun K. Ghosh et al.   JOURNAL OF NEUROCHEMISTRY

γ-Secretase inhibitors and modulators for Alzheimer’s disease

(2011) Michael S. Wolfe   JOURNAL OF NEUROCHEMISTRY

Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

(2011) Rafael León et al.   MEDICINAL RESEARCH REVIEWS

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE