Specific genomic cues regulate Cajal body assembly

Architectural RNAs (arcRNAs): A class of long noncoding RNAs that function as the scaffold of nuclear bodies

(2016) Takeshi Chujo et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Cycling in the nucleus: regulation of RNA 3′ processing and nuclear organization of replication-dependent histone genes

(2016) Valentina Romeo et al.   CURRENT OPINION IN CELL BIOLOGY

Droplet organelles?

(2016) Edward M Courchaine et al.   EMBO JOURNAL

Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity

(2016) Ke-Jun Han et al.   HUMAN MOLECULAR GENETICS

Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis

(2016) Deirdre C. Tatomer et al.   JOURNAL OF CELL BIOLOGY

Nuclear bodies: Built to boost

(2016) Iain A. Sawyer et al.   JOURNAL OF CELL BIOLOGY

Phase Separation: Linking Cellular Compartmentalization to Disease

(2016) Adriano Aguzzi et al.   TRENDS IN CELL BIOLOGY

Overexpression of the scaffold WD40 protein WRAP53β enhances the repair of and cell survival from DNA double-strand breaks

(2016) H Rassoolzadeh et al.   Cell Death & Disease

Cajal bodies are linked to genome conformation

(2016) Qiuyan Wang et al.   Nature Communications

In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes

(2016) Hermann Broder Schmidt et al.   Cell Reports

Spectral imaging to visualize higher-order genomic organization

(2016) Iain A. Sawyer et al.   Nucleus

Spectral imaging to visualize higher-order genomic organization

(2016) Iain A. Sawyer et al.   Nucleus

PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD)

(2015) Tamara Ratovitski et al.   CELL CYCLE

Nuclear bodies: the emerging biophysics of nucleoplasmic phases

(2015) Lian Zhu et al.   CURRENT OPINION IN CELL BIOLOGY

Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle

(2015) Jacob M. Vogan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomeric Properties of Survival Motor Neuron·Gemin2 Complexes

(2015) Kushol Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

(2015) Sven Hennig et al.   JOURNAL OF CELL BIOLOGY

RNA Controls PolyQ Protein Phase Transitions

(2015) Huaiying Zhang et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

Macromolecular crowding creates heterogeneous environments of gene expression in picolitre droplets

(2015) Maike M. K. Hansen et al.   Nature Nanotechnology

Transcriptome-wide dynamics of RNA pseudouridylation

(2015) John Karijolich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes

(2015) A Sveen et al.   ONCOGENE

RNA transcription modulates phase transition-driven nuclear body assembly

(2015) Joel Berry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coilin: The first 25 years

(2015) Martin Machyna et al.   RNA Biology

Phase separation of a Lennard-Jones fluid interacting with a long, condensed polymer chain: implications for the nuclear body formation near chromosomes

(2015) Inrok Oh et al.   Soft Matter

MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex

(2015) Hidehisa Takahashi et al.   Nature Communications

VRK1 regulates Cajal body dynamics and protects coilin from proteasomal degradation in cell cycle

(2015) Lara Cantarero et al.   Scientific Reports

SART3-Dependent Accumulation of Incomplete Spliceosomal snRNPs in Cajal Bodies

(2015) Ivan Novotný et al.   Cell Reports

The emerging landscape of small nucleolar RNAs in cell biology

(2015) Fabien Dupuis-Sandoval et al.   Wiley Interdisciplinary Reviews-RNA

The many faces of small nucleolar RNAs

(2014) Tomaž Bratkovič et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Connecting the Dots: The Effects of Macromolecular Crowding on Cell Physiology

(2014) Márcio A. Mourão et al.   BIOPHYSICAL JOURNAL

The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair

(2014) Sofia Henriksson et al.   GENES & DEVELOPMENT

Fam118B, a newly identified component of Cajal bodies, is required for Cajal body formation, snRNP biogenesis and cell viability

(2014) Y. Li et al.   JOURNAL OF CELL SCIENCE

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II

(2014) S. Hutten et al.   JOURNAL OF CELL SCIENCE

The Coilin Interactome Identifies Hundreds of Small Noncoding RNAs that Traffic through Cajal Bodies

(2014) Martin Machyna et al.   MOLECULAR CELL

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting vertebrate intron-encoded box C/D 2′-O-methylation guide RNAs into the Cajal body

(2014) Aline Marnef et al.   NUCLEIC ACIDS RESEARCH

Dynamic control of Cajal body number during zebrafish embryogenesis

(2014) Magdalena Strzelecka et al.   Nucleus

Signals controlling Cajal body assembly and function

(2013) Michael D. Hebert   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Whole-genome screening identifies proteins localized to distinct nuclear bodies

(2013) Ka-wing Fong et al.   JOURNAL OF CELL BIOLOGY

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

(2013) Tetsuro Hirose et al.   MOLECULAR BIOLOGY OF THE CELL

Plant Coilin: Structural Characteristics and RNA-Binding Properties

(2013) Valentine Makarov et al.   PLoS One

Regulation of Neuronal Differentiation by Proteins Associated with Nuclear Bodies

(2013) Benjamin Förthmann et al.   PLoS One

Crowding Effects on the Formation and Maintenance of Nuclear Bodies: Insights from Molecular-Dynamics Simulations of Simple Spherical Model Particles

(2012) Eun Jin Cho et al.   BIOPHYSICAL JOURNAL

Nuclear bodies: multifunctional companions of the genome

(2012) Miroslav Dundr   CURRENT OPINION IN CELL BIOLOGY

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

The integrator complex is required for integrity of Cajal bodies

(2012) H. Takata et al.   JOURNAL OF CELL SCIENCE

Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently

(2012) J. L. Stern et al.   MOLECULAR AND CELLULAR BIOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The Survival Motor Neuron Protein Forms Soluble Glycine Zipper Oligomers

(2012) Renee Martin et al.   STRUCTURE

Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells

(2012) Yeh-Chuin Poh et al.   Nature Communications

Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion

(2012) Cyrille Girard et al.   Nature Communications

Genomic Study of RNA Polymerase II and III SNAPc-Bound Promoters Reveals a Gene Transcribed by Both Enzymes and a Broad Use of Common Activators

(2012) Nicole James Faresse et al.   PLoS Genetics

Cajal bodies: where form meets function

(2012) Martin Machyna et al.   Wiley Interdisciplinary Reviews-RNA

SNOntology: Myriads of novel snornas or just a mirage?

(2011) Julia A Makarova et al.   BMC GENOMICS

A view of nuclear Polycomb bodies

(2011) Vincenzo Pirrotta et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Seed and grow: a two-step model for nuclear body biogenesis: Figure 1.

(2011) Miroslav Dundr   JOURNAL OF CELL BIOLOGY

Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications

(2011) Marta Sanz-García et al.   Journal of Proteomics

Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage

(2011) Andrew S. Gilder et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleation of nuclear bodies by RNA

(2011) Sergey P. Shevtsov et al.   NATURE CELL BIOLOGY

Coilin Phosphomutants Disrupt Cajal Body Formation, Reduce Cell Proliferation and Produce a Distinct Coilin Degradation Product

(2011) Zunamys I. Carrero et al.   PLoS One

Biogenesis and function of nuclear bodies

(2011) Yuntao S. Mao et al.   TRENDS IN GENETICS

snRNA 3′ end formation: the dawn of the Integrator complex

(2010) Jiandong Chen et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The proteins of intra-nuclear bodies: a data-driven analysis of sequence, interaction and expression

(2010) Nurul Mohamad et al.   BMC Systems Biology

Depletion of hCINAP by RNA interference causes defects in Cajal body formation, histone transcription, and cell viability

(2010) Jinfang Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulation of snRNA gene expression by theDrosophila melanogastersmall nuclear RNA activating protein complex (DmSNAPc)

(2010) Ko-Hsuan Hung et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Solution structure of the carboxy-terminal Tudor domain from human Coilin

(2010) Riya Shanbhag et al.   FEBS LETTERS

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs

(2010) Yuntao S. Mao et al.   NATURE CELL BIOLOGY

Orphan Nuclear Bodies

(2010) M. Carmo-Fonseca et al.   Cold Spring Harbor Perspectives in Biology

The Cajal Body and Histone Locus Body

(2010) Z. Nizami et al.   Cold Spring Harbor Perspectives in Biology

Biogenesis of Nuclear Bodies

(2010) M. Dundr et al.   Cold Spring Harbor Perspectives in Biology

WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies

(2010) Salah Mahmoudi et al.   PLOS BIOLOGY

Coilin phosphorylation mediates interaction with SMN and SmB′

(2009) Cory G. Toyota et al.   CHROMOSOMA

Nuclear Bodies: Random Aggregates of Sticky Proteins or Crucibles of Macromolecular Assembly?

(2009) A. Gregory Matera et al.   DEVELOPMENTAL CELL

Cajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell lines

(2009) S. M. Hearst et al.   JOURNAL OF CELL SCIENCE

Coilin Is Essential for Cajal Body Organization in Drosophila melanogaster

(2009) Ji-Long Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Macromolecular crowding and its potential impact on nuclear function

(2008) Karsten Richter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Cajal body

(2008) Glenn E. Morris   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Spliceosomal Small Nuclear Ribonucleoprotein Particles Repeatedly Cycle through Cajal Bodies

(2008) David Staněk et al.   MOLECULAR BIOLOGY OF THE CELL

Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

(2008) P. N. Ghule et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De Novo Formation of a Subnuclear Body

(2008) T. E. Kaiser et al.   SCIENCE