Linking replication stress with heterochromatin formation

Chromatin plasticity in response to DNA damage: The shape of things to come

(2015) Salomé Adam et al.   DNA REPAIR

Heterochromatin formation via recruitment of DNA repair proteins

(2015) Jacob G. Kirkland et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptional Elongation Factor ENL Phosphorylated by ATM Recruits Polycomb and Switches Off Transcription for DSB Repair

(2015) Ayako Ui et al.   MOLECULAR CELL

Constitutive heterochromatin formation and transcription in mammals

(2015) Nehmé Saksouk et al.   Epigenetics & Chromatin

Histone lysine methylation and chromatin replication

(2014) Carlos Rivera et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Chromatin maintenance and dynamics in senescence: a spotlight on SAHF formation and the epigenome of senescent cells

(2014) Armelle Corpet et al.   CHROMOSOMA

Nucleolus and nuclear periphery: Velcro for heterochromatin

(2014) Jan Padeken et al.   CURRENT OPINION IN CELL BIOLOGY

Metabolism of DNA secondary structures at the eukaryotic replication fork

(2014) Ana María León-Ortiz et al.   DNA REPAIR

Double strand break (DSB) repair in heterochromatin and heterochromatin proteins in DSB repair

(2014) Charlène Lemaître et al.   DNA REPAIR

Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells

(2014) D. Schiavone et al.   EMBO JOURNAL

RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress

(2014) Magtouf Gatei et al.   HUMAN MOLECULAR GENETICS

Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin

(2014) Andreas Kakarougkas et al.   MOLECULAR CELL

The maintenance of chromosome structure: positioning and functioning of SMC complexes

(2014) Kristian Jeppsson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Direct interactions promote eviction of the Sir3 heterochromatin protein by the SWI/SNF chromatin remodeling enzyme

(2014) Benjamin J. Manning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin

(2014) M. K. Ayrapetov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIR Proteins and the Assembly of Silent Chromatin in Budding Yeast

(2013) Stephanie Kueng et al.   Annual Review of Genetics

Loss of WSTF results in spontaneous fluctuations of heterochromatin formation and resolution, combined with substantial changes to gene expression

(2013) Ashley E Culver-Cochran et al.   BMC GENOMICS

Brc1 links replication stress response and centromere function

(2013) Si Young Lee et al.   CELL CYCLE

Differential contribution of HP1 proteins to DNA end resection and homology-directed repair

(2013) Gaston Soria et al.   CELL CYCLE

Building silent compartments at the nuclear periphery: a recurrent theme

(2013) Peter Meister et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

SIR–nucleosome interactions: Structure–function relationships in yeast silent chromatin

(2013) Mariano Oppikofer et al.   GENE

Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3

(2013) P. K. Chan et al.   HUMAN MOLECULAR GENETICS

FANCJ couples replication past natural fork barriers with maintenance of chromatin structure

(2013) Rebekka A. Schwab et al.   JOURNAL OF CELL BIOLOGY

 H2A-Binding Protein Brc1 Affects Centromere Function in Fission Yeast

(2013) S. Y. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Pif1 family helicases suppress genome instability at G-quadruplex motifs

(2013) Katrin Paeschke et al.   NATURE

Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency

(2013) Rupa Sridharan et al.   NATURE CELL BIOLOGY

MRX protects fork integrity at protein–DNA barriers, and its absence causes checkpoint activation dependent on chromatin context

(2013) Iben B. Bentsen et al.   NUCLEIC ACIDS RESEARCH

Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements

(2013) Claudio P. Albuquerque et al.   PLoS Genetics

Structure and Function in the Budding Yeast Nucleus

(2012) A. Taddei et al.   GENETICS

The emerging role of Polycomb repressors in the response to DNA damage

(2012) Joseph H. A. Vissers et al.   JOURNAL OF CELL SCIENCE

Cohesin Association to Replication Sites Depends on Rad50 and Promotes Fork Restart

(2012) Mireille Tittel-Elmer et al.   MOLECULAR CELL

R Loops: From Transcription Byproducts to Threats to Genome Stability

(2012) Andrés Aguilera et al.   MOLECULAR CELL

DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9

(2012) Patrice Y. Ohouo et al.   NATURE

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

(2012) Raphaël Rodriguez et al.   Nature Chemical Biology

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

Chromatin replication and epigenome maintenance

(2012) Constance Alabert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A transcription factor–based mechanism for mouse heterochromatin formation

(2012) Aydan Bulut-Karslioglu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

γH2A is a component of yeast heterochromatin required for telomere elongation

(2011) Tasuku Kitada et al.   CELL CYCLE

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a

(2011) Martin Kosar et al.   CELL CYCLE

Reinventing Heterochromatin in Budding Yeasts: Sir2 and the Origin Recognition Complex Take Center Stage

(2011) Meleah A. Hickman et al.   EUKARYOTIC CELL

Tight protein-DNA interactions favor gene silencing

(2011) M. Dubarry et al.   GENES & DEVELOPMENT

How does genome instability affect lifespan?

(2011) Takehiko Kobayashi   GENES TO CELLS

HP1α recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair

(2011) Céline Baldeyron et al.   JOURNAL OF CELL BIOLOGY

RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II

(2011) Mikel Zaratiegui et al.   NATURE

Coordination of DNA replication and histone modification by the Rik1–Dos2 complex

(2011) Fei Li et al.   NATURE

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin

(2011) Christèle Maison et al.   NATURE GENETICS

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA

(2011) Peter Sarkies et al.   NUCLEIC ACIDS RESEARCH

Targeted Sister Chromatid Cohesion by Sir2

(2011) Ching-Shyi Wu et al.   PLoS Genetics

Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity

(2010) Elizabeth H. Bayne et al.   CELL

γH2A binds Brc1 to maintain genome integrity during S-phase

(2010) Jessica S Williams et al.   EMBO JOURNAL

Ume6 Is Required for the MATa/MAT  Cellular Identity and Transcriptional Silencing in Kluyveromyces lactis

(2010) E. Barsoum et al.   GENETICS

Cul8/Rtt101 Forms a Variety of Protein Complexes That Regulate DNA Damage Response and Transcriptional Silencing

(2010) Satoru Mimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saccharomyces cerevisiaeEsc2p Interacts with Sir2p through a Small Ubiquitin-like Modifier (SUMO)-binding Motif and Regulates Transcriptionally Silent Chromatin in a Locus-dependent Manner

(2010) Qun Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Smc5/6 Complex and Esc2 Influence Multiple Replication-associated Recombination Processes in Saccharomyces cerevisiae

(2010) Koyi Choi et al.   MOLECULAR BIOLOGY OF THE CELL

DNA Damage Signaling Recruits the Rtt107-Slx4 Scaffolds via Dpb11 to Mediate Replication Stress Response

(2010) Patrice Y. Ohouo et al.   MOLECULAR CELL

CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR

(2010) Mikel Zaratiegui et al.   NATURE

Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX

(2010) Rachel K Szilard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of the Epigenetic Regulator HP1γ in the Control of Embryonic Stem Cell Properties

(2010) Maïa Caillier et al.   PLoS One

Transcriptional silencing functions of the yeast protein Orc1/Sir3 subfunctionalized after gene duplication

(2010) M. A. Hickman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The interface between transcription and mechanisms maintaining genome integrity

(2010) Jesper Q. Svejstrup   TRENDS IN BIOCHEMICAL SCIENCES

Rad3ATR Decorates Critical Chromosomal Domains with γH2A to Protect Genome Integrity during S-Phase in Fission Yeast

(2010) Sophie Rozenzhak et al.   PLoS Genetics

A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence

(2009) N. Humbert et al.   CANCER RESEARCH

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

(2009) Alejandra Loyola et al.   EMBO REPORTS

Esc2 and Sgs1 Act in Functionally Distinct Branches of the Homologous Recombination Repair Pathway in Saccharomyces cerevisiae

(2009) Hocine W. Mankouri et al.   MOLECULAR BIOLOGY OF THE CELL

The Saccharomyces cerevisiae Esc2 and Smc5-6 Proteins Promote Sister Chromatid Junction-mediated Intra-S Repair

(2009) Julie Sollier et al.   MOLECULAR BIOLOGY OF THE CELL

Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae

(2009) Anna Azvolinsky et al.   MOLECULAR CELL

RNA Interference Guides Histone Modification during the S Phase of Chromosomal Replication

(2008) Anna Kloc et al.   CURRENT BIOLOGY

ATR signaling can drive cells into senescence in the absence of DNA breaks

(2008) L. I. Toledo et al.   GENES & DEVELOPMENT

HP1-β is required for development of the cerebral neocortex and neuromuscular junctions

(2008) Rebecca Aucott et al.   JOURNAL OF CELL BIOLOGY

HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Nonoverlapping Mechanisms

(2008) Mohammad R. Motamedi et al.   MOLECULAR CELL

Mutations in deoxyribonucleotide biosynthesis pathway cause spreading of silencing across heterochromatic barriers at the mating-type region of the fission yeast

(2007) Gurjeet Singh et al.   YEAST