Brc1 links replication stress response and centromere function

 H2A-Binding Protein Brc1 Affects Centromere Function in Fission Yeast

(2013) S. Y. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair

(2012) Xinxin Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brc1-dependent recovery from replication stress

(2012) K. L. Bass et al.   JOURNAL OF CELL SCIENCE

Phosphorylation-Dependent Interactions between Crb2 and Chk1 Are Essential for DNA Damage Checkpoint

(2012) Meng Qu et al.   PLoS Genetics

The Cul4-Ddb1Cdt2 Ubiquitin Ligase Inhibits Invasion of a Boundary-Associated Antisilencing Factor into Heterochromatin

(2011) Sigurd Braun et al.   CELL

Phosphorylation-regulated binding of Ctp1 to Nbs1 is critical for repair of DNA double-strand breaks

(2011) Gerald E. Dodson et al.   CELL CYCLE

Structural basis of γH2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathway

(2011) Wei Yan et al.   FEBS LETTERS

RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II

(2011) Mikel Zaratiegui et al.   NATURE

Coordination of DNA replication and histone modification by the Rik1–Dos2 complex

(2011) Fei Li et al.   NATURE

Release of Ku and MRN from DNA Ends by Mre11 Nuclease Activity and Ctp1 Is Required for Homologous Recombination Repair of Double-Strand Breaks

(2011) Petra Langerak et al.   PLoS Genetics

γH2A binds Brc1 to maintain genome integrity during S-phase

(2010) Jessica S Williams et al.   EMBO JOURNAL

DNA Damage Signaling Recruits the Rtt107-Slx4 Scaffolds via Dpb11 to Mediate Replication Stress Response

(2010) Patrice Y. Ohouo et al.   MOLECULAR CELL

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks

(2010) Matthew L Nicolette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PTIP Promotes Chromatin Changes Critical for Immunoglobulin Class Switch Recombination

(2010) J. A. Daniel et al.   SCIENCE

Rad3ATR Decorates Critical Chromosomal Domains with γH2A to Protect Genome Integrity during S-Phase in Fission Yeast

(2010) Sophie Rozenzhak et al.   PLoS Genetics

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

(2009) R. Scott Williams et al.   CELL

A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage

(2009) Janette Lloyd et al.   CELL

H2AX: functional roles and potential applications

(2009) Jennifer S. Dickey et al.   CHROMOSOMA

DNA end resection: Many nucleases make light work

(2009) Eleni P. Mimitou et al.   DNA REPAIR

PTIP Regulates 53BP1 and SMC1 at the DNA Damage Sites

(2009) Jiaxue Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

(2009) S. Kosugi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

(2009) S. A. Kawashima et al.   SCIENCE

PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage

(2008) Thomas Göhler et al.   DNA REPAIR

Localization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively

(2008) Stephanie Pebernard et al.   EMBO JOURNAL

Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair

(2008) M. L. Kilkenny et al.   GENES & DEVELOPMENT

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY