A new role of neuraminidase (NA) in the influenza virus life cycle: implication for developing NA inhibitors with novel mechanism of action

Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2013–2014

(2015) Emi Takashita et al.   ANTIVIRAL RESEARCH

Influenza Viruses with Receptor-Binding N1 Neuraminidases Occur Sporadically in Several Lineages and Show No Attenuation in Cell Culture or Mice

(2015) Kathryn A. Hooper et al.   JOURNAL OF VIROLOGY

The neuraminidases of MDCK grown human influenza A(H3N2) viruses isolated since 1994 can demonstrate receptor binding

(2015) Peter G Mohr et al.   Virology Journal

The combination of ribavirin and ozeltamivir effectively inhibits reproduction of influenza a virus resistant to rimantadine (Amantadine) in vitro and in vivo

(2014) P. G. Deryabin et al.   Doklady Biochemistry and Biophysics

From neuraminidase inhibitors to conjugates: a step towards better anti-influenza drugs?

(2014) Chung-Kai Cheng et al.   Future Medicinal Chemistry

Post-marketing safety and effectiveness evaluation of the intravenous anti-influenza neuraminidase inhibitor peramivir (I): A drug use investigation

(2014) Takuji Komeda et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Recent H3N2 Influenza Virus Clinical Isolates Rapidly Acquire Hemagglutinin or Neuraminidase Mutations When Propagated for Antigenic Analyses

(2014) B. S. Chambers et al.   JOURNAL OF VIROLOGY

Antiviral combinations for severe influenza

(2014) Jake Dunning et al.   LANCET INFECTIOUS DISEASES

Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein

(2014) Shuai Xia et al.   VIRUS RESEARCH

Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor

(2013) Sankar Mohan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The effect of the MDCK cell selected neuraminidase D151G mutation on the drug susceptibility assessment of influenza A(H3N2) viruses

(2013) Vasiliy P. Mishin et al.   ANTIVIRAL RESEARCH

Exploitation of the Catalytic Site and 150 Cavity for Design of Influenza A Neuraminidase Inhibitors

(2013) Pal John Pal Adabala et al.   JOURNAL OF ORGANIC CHEMISTRY

A Mutant Influenza Virus That Uses an N1 Neuraminidase as the Receptor-Binding Protein

(2013) Kathryn A. Hooper et al.   JOURNAL OF VIROLOGY

Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance

(2013) Yunwen Hu et al.   LANCET

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

NA Proteins of Influenza A Viruses H1N1/2009, H5N1, and H9N2 Show Differential Effects on Infection Initiation, Virus Release, and Cell-Cell Fusion

(2013) Quanjiao Chen et al.   PLoS One

Human H3N2 Influenza Viruses Isolated from 1968 To 2012 Show Varying Preference for Receptor Substructures with No Apparent Consequences for Disease or Spread

(2013) Shelly Gulati et al.   PLoS One

Comparison of Mutation Patterns in Full-Genome A/H3N2 Influenza Sequences Obtained Directly from Clinical Samples and the Same Samples after a Single MDCK Passage

(2013) Hong Kai Lee et al.   PLoS One

Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China

(2013) Kunkun Zhao et al.   VETERINARY MICROBIOLOGY

Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase

(2013) Miriam Cohen et al.   Virology Journal

Influenza A Virus Entry Inhibitors Targeting the Hemagglutinin

(2013) Jie Yang et al.   Viruses-Basel

Recent Advances in the Structure-Based Design of Neuraminidase Inhibitors as Antiinfluenza Agents

(2012) Yuanyuan Shan et al.   CURRENT MEDICINAL CHEMISTRY

Structure–activity relationships of saponin derivatives: A series of entry inhibitors for highly pathogenic H5N1 influenza virus

(2012) Ning Ding et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Clinical effectiveness of neuraminidase inhibitors—oseltamivir, zanamivir, laninamivir, and peramivir—for treatment of influenza A(H3N2) and A(H1N1)pdm09 infection: an observational study in the 2010–2011 influenza season in Japan

(2012) Yugo Shobugawa et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Influenza Virus Neuraminidases with Reduced Enzymatic Activity That Avidly Bind Sialic Acid Receptors

(2012) X. Zhu et al.   JOURNAL OF VIROLOGY

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry

(2011) Shuwen Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A natural theaflavins preparation inhibits HIV-1 infection by targeting the entry step: Potential applications for preventing HIV-1 infection

(2011) Jie Yang et al.   FITOTERAPIA

Detection of E119V and E119I Mutations in Influenza A (H3N2) Viruses Isolated from an Immunocompromised Patient: Challenges in Diagnosis of Oseltamivir Resistance

(2010) M. Okomo-Adhiambo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dual Resistance to Adamantanes and Oseltamivir Among Seasonal Influenza A(H1N1) Viruses: 2008–2010

(2010) Tiffany G. Sheu et al.   JOURNAL OF INFECTIOUS DISEASES

Carbocycles Related to Oseltamivir as Influenza Virus Group-1-Specific Neuraminidase Inhibitors. Binding to N1 Enzymes in the Context of Virus-like Particles

(2010) Sankar Mohan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Neuraminidase Receptor Binding Variants of Human Influenza A(H3N2) Viruses Resulting from Substitution of Aspartic Acid 151 in the Catalytic Site: a Role in Virus Attachment?

(2010) Y. P. Lin et al.   JOURNAL OF VIROLOGY

Receptor Specificity of Influenza A H3N2 Viruses Isolated in Mammalian Cells and Embryonated Chicken Eggs

(2010) J. Stevens et al.   JOURNAL OF VIROLOGY

Triple Combination of Oseltamivir, Amantadine, and Ribavirin Displays Synergistic Activity against Multiple Influenza Virus Strains In Vitro

(2009) J. T. Nguyen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of H274Y oseltamivir-resistant A(H1N1) influenza viruses in Japan during the 2008–2009 season

(2009) Tatiana Baranovich et al.   JOURNAL OF CLINICAL VIROLOGY

Enhancement of the Influenza A Hemagglutinin (HA)-Mediated Cell-Cell Fusion and Virus Entry by the Viral Neuraminidase (NA)

(2009) Bin Su et al.   PLoS One

Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

(2009) R. J. Garten et al.   SCIENCE