Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor

Structural basis for a class of nanomolar influenza A neuraminidase inhibitors

(2013) Philip S. Kerry et al.   Scientific Reports

Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance

(2012) Jennifer L. McKimm-Breschkin   Influenza and Other Respiratory Viruses

Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site

(2012) X. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus

(2012) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication inhibition activity of carbocycles related to oseltamivir on influenza A virus in vitro

(2011) Masahiro Niikura et al.   ANTIVIRAL RESEARCH

Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes

(2011) Amgad Albohy et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Influenza neuraminidase: A druggable target for natural products

(2011) Ulrike Grienke et al.   NATURAL PRODUCT REPORTS

Mechanism of 150-cavity formation in influenza neuraminidase

(2011) Rommie E. Amaro et al.   Nature Communications

Carbocycles Related to Oseltamivir as Influenza Virus Group-1-Specific Neuraminidase Inhibitors. Binding to N1 Enzymes in the Context of Virus-like Particles

(2010) Sankar Mohan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

(2010) Santosh Rudrawar et al.   Nature Communications

Characterizing Loop Dynamics and Ligand Recognition in Human- and Avian-Type Influenza Neuraminidases via Generalized Born Molecular Dynamics and End-Point Free Energy Calculations

(2009) Rommie E. Amaro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for oseltamivir resistance of influenza viruses

(2009) P.J. Collins et al.   VACCINE

Limited Inhibitory Effects of Oseltamivir and Zanamivir on Human Sialidases

(2008) K. Hata et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

(2008) Patrick J. Collins et al.   NATURE