DNA Mismatch Repair and Oxidative DNA Damage: Implications for Cancer Biology and Treatment

PARP inhibitors in ovarian cancer: Current status and future promise

(2014) Joyce F. Liu et al.   GYNECOLOGIC ONCOLOGY

Mismatch Repair Deficient Mice Show Susceptibility to Oxidative Stress-Induced Intestinal Carcinogenesis

(2014) Jingshu Piao et al.   International Journal of Biological Sciences

Synergistic Induction of Apoptosis by Methylseleninic Acid and Cisplatin, The Role of ROS-ERK/AKT-p53 Pathway

(2014) Yibo Zhang et al.   MOLECULAR PHARMACEUTICS

Antibiotics induce redox-related physiological alterations as part of their lethality

(2014) D. J. Dwyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paradoxical Effects of Antioxidants on Cancer

(2014) Andrew R. Mendelsohn et al.   REJUVENATION RESEARCH

Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress

(2013) M Hewish et al.   BRITISH JOURNAL OF CANCER

Mismatch repair deficiency in ovarian cancer — Molecular characteristics and clinical implications

(2013) Xue Xiao et al.   GYNECOLOGIC ONCOLOGY

Reactive Oxygen Species in the Immune System

(2013) Yuhui Yang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

(2013) Steven A Roberts et al.   NATURE GENETICS

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer

(2013) A D'Anneo et al.   Cell Death & Disease

Oxidative Stress and the DNA Mismatch Repair Pathway

(2012) David J. Brierley et al.   ANTIOXIDANTS & REDOX SIGNALING

Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells

(2012) Wei-Hsin Chiu et al.   BIOCHEMICAL PHARMACOLOGY

Oxidatively induced DNA damage: Mechanisms, repair and disease

(2012) Miral Dizdaroglu   CANCER LETTERS

An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

(2012) X. Huang et al.   CANCER RESEARCH

Nucleotide excision repair: new tricks with old bricks

(2012) Irene Kamileri et al.   TRENDS IN GENETICS

Parallel High-Throughput RNA Interference Screens Identify PINK1 as a Potential Therapeutic Target for the Treatment of DNA Mismatch Repair-Deficient Cancers

(2011) S. A. Martin et al.   CANCER RESEARCH

The hMsh2-hMsh6 Complex Acts in Concert with Monoubiquitinated PCNA and Pol η in Response to Oxidative DNA Damage in Human Cells

(2011) Anastasia Zlatanou et al.   MOLECULAR CELL

Role of oxidative stress and DNA damage in human carcinogenesis

(2011) Thomas B. Kryston et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Base Excision Repair, the Redox Environment and Therapeutic Implications

(2011) S. J. Storr et al.   Current Molecular Pharmacology

Overview of Base Excision Repair Biochemistry

(2011) Yun-Jeong Kim et al.   Current Molecular Pharmacology

Base Excision Repair and Lesion-Dependent Subpathways for Repair of Oxidative DNA Damage

(2010) David Svilar et al.   ANTIOXIDANTS & REDOX SIGNALING

DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1

(2010) Sarah A. Martin et al.   CANCER CELL

Therapeutic Targeting of the DNA Mismatch Repair Pathway

(2010) S. A. Martin et al.   CLINICAL CANCER RESEARCH

Mismatch repair status and outcomes after adjuvant therapy in patients with surgically staged endometrial cancer

(2010) Kimberly E. Resnick et al.   GYNECOLOGIC ONCOLOGY

Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival

(2010) Evelyne Sage et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Mismatch repair deficient colorectal cancer in the era of personalized treatment

(2010) Madeleine Hewish et al.   Nature Reviews Clinical Oncology

Mitochondrial DNA mutations and human disease

(2009) Helen A.L. Tuppen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Role of MUTYH and MSH2 in the Control of Oxidative DNA Damage, Genetic Instability, and Tumorigenesis

(2009) M. T. Russo et al.   CANCER RESEARCH

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria

(2009) Nadja C. de Souza-Pinto et al.   DNA REPAIR

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair geneMSH2

(2009) Sarah A. Martin et al.   EMBO Molecular Medicine

DNA Mismatch Repair Deficiency in Endometrial Carcinoma

(2009) Yevgeniy Karamurzin et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

Compromised repair of clustered DNA damage in the human acute lymphoblastic leukemia MSH2-deficient NALM-6 cells

(2008) Stewart M. Holt et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS