Reversal of pentylenetetrazole-altered swimming and neural activity-regulated gene expression in zebrafish larvae by valproic acid and valerian extract

Age matters: Developmental stage of Danio rerio larvae influences photomotor response thresholds to diazinion or diphenhydramine

(2016) Lauren A. Kristofco et al.   AQUATIC TOXICOLOGY

Effects of Npas4 deficiency on anxiety, depression-like, cognition and sociability behaviour

(2015) Emily J. Jaehne et al.   BEHAVIOURAL BRAIN RESEARCH

Valerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish)

(2015) Bianca A. Torres-Hernández et al.   BMC Complementary and Alternative Medicine

15 years of zebrafish chemical screening

(2015) Andrew J Rennekamp et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Zebrafish as tools for drug discovery

(2015) Calum A. MacRae et al.   NATURE REVIEWS DRUG DISCOVERY

Zebrafish Bioassay-Guided Microfractionation Identifies Anticonvulsant Steroid Glycosides from the Philippine Medicinal Plant Solanum torvum

(2014) Soura Challal et al.   ACS Chemical Neuroscience

The anxiolytic effects of a Valerian extract is based on Valerenic acid

(2014) Axel Becker et al.   BMC Complementary and Alternative Medicine

Npas4 Regulates Excitatory-Inhibitory Balance within Neural Circuits through Cell-Type-Specific Gene Programs

(2014) Ivo Spiegel et al.   CELL

A Defined Zebrafish Line for High-Throughput Genetics and Genomics: NHGRI-1

(2014) Matthew C. LaFave et al.   GENETICS

The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development

(2014) Matthew O. Parker et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition

(2013) Brenda L. Bloodgood et al.   NATURE

Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products

(2013) Nadine Bohni et al.   PLoS One

Prey capture in zebrafish larvae serves as a model to study cognitive functions

(2013) Akira Muto et al.   Frontiers in Neural Circuits

A larval zebrafish model of bipolar disorder as a screening platform for neuro-therapeutics

(2012) Lee David Ellis et al.   BEHAVIOURAL BRAIN RESEARCH

Distinct models of induced hyperactivity in zebrafish larvae

(2012) Lee David Ellis et al.   BRAIN RESEARCH

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

(2012) S. Baxendale et al.   Disease Models & Mechanisms

Npas4: A Neuronal Transcription Factor with a Key Role in Social and Cognitive Functions Relevant to Developmental Disorders

(2012) Laurence Coutellier et al.   PLoS One

Selective Interactions ofValeriana officinalisExtracts and Valerenic Acid with [3H]Glutamate Binding to Rat Synaptic Membranes

(2011) Lisa M. Del Valle-Mojica et al.   Evidence-based Complementary and Alternative Medicine

Aqueous and EthanolicValeriana officinalisExtracts Change the Binding of Ligands to Glutamate Receptors

(2010) Lisa M. Del Valle-Mojica et al.   Evidence-based Complementary and Alternative Medicine

Biomedically relevant chemical constituents of Valeriana officinalis

(2010) Jiří Patočka et al.   Journal of Applied Biomedicine

Molecular and Therapeutic Potential and Toxicity of Valproic Acid

(2010) Sébastien Chateauvieux et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Effectiveness of Valerian on insomnia: A meta-analysis of randomized placebo-controlled trials

(2010) Ma Isabel Fernández-San-Martín et al.   SLEEP MEDICINE

Anticonvulsant effect of aqueous extract of Valeriana officinalis in amygdala-kindled rats: Possible involvement of adenosine

(2009) Mohammad Ebrahim Rezvani et al.   JOURNAL OF ETHNOPHARMACOLOGY

New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function

(2009) M. E. Greenberg et al.   JOURNAL OF NEUROSCIENCE

Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats

(2009) K. Murphy et al.   PHYTOMEDICINE

Sodium valproate: an old drug with new roles

(2009) Natalia N. Nalivaeva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience

Activity-dependent regulation of inhibitory synapse development by Npas4

(2008) Yingxi Lin et al.   NATURE

GABAA receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts

(2008) Dietmar Benke et al.   NEUROPHARMACOLOGY

Locomotion in larval zebrafish: Influence of time of day, lighting and ethanol

(2008) R.C. MacPhail et al.   NEUROTOXICOLOGY

Modulation of GABAA Receptors by Valerian Extracts is Related to the Content of Valerenic Acid

(2008) Gabriele Trauner et al.   PLANTA MEDICA

A randomized clinical trial of valerian fails to improve self-reported, polysomnographic, and actigraphic sleep in older women with insomnia

(2008) Diana M. Taibi et al.   SLEEP MEDICINE

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols

Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties

(2007) Miguel Hattesohl et al.   PHYTOMEDICINE