Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products

High resolution ultra high pressure liquid chromatography–time-of-flight mass spectrometry dereplication strategy for the metabolite profiling of Brazilian Lippia species

(2012) Cristiano S. Funari et al.   JOURNAL OF CHROMATOGRAPHY A

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Discovery of novel anti-inflammatory drug-like compounds by aligning in silico and in vivo screening: The nitroindazolinone chemotype

(2011) Yovani Marrero-Ponce et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

From Retrospective Assessment to Prospective Decisions in Natural Product Isolation: HPLC-SPE-NMR Analysis ofCarthamus oxyacantha

(2011) Kenneth T. Johansen et al.   JOURNAL OF NATURAL PRODUCTS

Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation

(2011) S. Vargas et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Impact of high-throughput screening in biomedical research

(2011) Ricardo Macarron et al.   NATURE REVIEWS DRUG DISCOVERY

Microgram-scale, in vivo natural product discovery using zebrafish bioassays, UHPLC-TOF-MS and microflow NMR: Identification of anticonvulsants in the Philippine medicinal plant Solanum torvum

(2011) AD Crawford et al.   PLANTA MEDICA

Isolation of Apoptosis-Inducing Stilbenoids from Four Members of the Orchidaceae Family

(2011) Russell Williams et al.   PLANTA MEDICA

Zebrafish Bioassay-Guided Natural Product Discovery: Isolation of Angiogenesis Inhibitors from East African Medicinal Plants

(2011) Alexander D. Crawford et al.   PLoS One

Privileged scaffolds for library design and drug discovery

(2010) Matthew E Welsch et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

1H NMR Fingerprinting of Soybean Extracts, with Emphasis on Identification and Quantification of Isoflavones

(2010) Augusta Caligiani et al.   Nutrients

Microfractionation Revisited: A 1536 Well High Resolution Screening Assay

(2009) Martin Giera et al.   ANALYTICAL CHEMISTRY

Some solutions to obtain very efficient separations in isocratic and gradient modes using small particles size and ultra-high pressure

(2009) Davy Guillarme et al.   JOURNAL OF CHROMATOGRAPHY A

Novel Chemical Space Exploration via Natural Products

(2009) Josefin Rosén et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure Elucidation at the Nanomole Scale. 1. Trisoxazole Macrolides and Thiazole-Containing Cyclic Peptides from the NudibranchHexabranchus sanguineus

(2009) Doralyn S. Dalisay et al.   JOURNAL OF NATURAL PRODUCTS

Isoflavonoids of the Leguminosae

(2009) Nigel C. Veitch   NATURAL PRODUCT REPORTS

Mass spectrometry-based metabolomics oriented by correlation analysis for wound-induced molecule discovery: identification of a novel jasmonate glucoside

(2009) Gaetan Glauser et al.   PHYTOCHEMICAL ANALYSIS

Nuclear Magnetic Resonance Spectroscopy as a Quantitative Tool To Determine the Concentrations of Biologically Produced Metabolites: Implications in Metabolites in Safety Testing

(2008) Robert Espina et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Natural products in drug discovery

(2008) A HARVEY   DRUG DISCOVERY TODAY

Fishing for Drugs from Nature: Zebrafish as a Technology Platform for Natural Product Discovery

(2008) Alexander Crawford et al.   PLANTA MEDICA

Method transfer for fast liquid chromatography in pharmaceutical analysis: Application to short columns packed with small particle. Part II: Gradient experiments

(2007) Davy Guillarme et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS