Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins

Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA

(2015) Simin Zheng et al.   CELL

Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase

(2015) Wenjun Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catalytic Pocket Inaccessibility of Activation-Induced Cytidine Deaminase Is a Safeguard against Excessive Mutagenic Activity

(2015) Justin J. King et al.   STRUCTURE

The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization

(2015) Markus-Frederik Bohn et al.   STRUCTURE

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

(2015) Shraddha Sharma et al.   Nature Communications

APOBEC3A Is Implicated in a Novel Class of G-to-A mRNA Editing in WT1 Transcripts

(2015) Ahmadreza Niavarani et al.   PLoS One

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47

(2014) N. Fossat et al.   EMBO REPORTS

The RNA-editing Enzyme APOBEC1 Requires Heterogeneous Nuclear Ribonucleoprotein Q Isoform 6 for Efficient Interaction with Interleukin-8 mRNA

(2014) Yuko Shimizu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequential Binding of Cytosolic Phox Complex to Phagosomes through Regulated Adaptor Proteins: Evaluation Using the Novel Monomeric Kusabira-Green System and Live Imaging of Phagocytosis

(2014) T. Ueyama et al.   JOURNAL OF IMMUNOLOGY

Interaction of APOBEC3A with DNA Assessed by Atomic Force Microscopy

(2014) Luda S. Shlyakhtenko et al.   PLoS One

APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination

(2014) Jianliang Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion

(2014) Somayeh Sabouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination

(2014) A. Zahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions

(2014) Kimberly M. Prohaska et al.   Wiley Interdisciplinary Reviews-RNA

Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver

(2014) Valerie Blanc et al.   GENOME BIOLOGY

Atomic force microscopy studies of APOBEC3G oligomerization and dynamics

(2013) Luda S. Shlyakhtenko et al.   JOURNAL OF STRUCTURAL BIOLOGY

A Tudor Domain Protein SPINDLIN1 Interacts with the mRNA-Binding Protein SERBP1 and Is Involved in Mouse Oocyte Meiotic Resumption

(2013) Ting Gang Chew et al.   PLoS One

APOBEC2 Is a Monomer in Solution: Implications for APOBEC3G Models

(2012) Troy C. Krzysiak et al.   BIOCHEMISTRY

A Structural Basis for the Biochemical Behavior of Activation-induced Deoxycytidine Deaminase Class-switch Recombination-defective Hyper-IgM-2 Mutants

(2012) Yunxiang Mu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation

(2012) Nasim A. Begum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Evolutionary View of the Mechanism for Immune and Genome Diversity

(2012) L. Kato et al.   JOURNAL OF IMMUNOLOGY

Nuclear to Cytoplasmic Translocation of Heterogeneous Nuclear Ribonucleoprotein U Enhances TLR-Induced Proinflammatory Cytokine Production by Stabilizing mRNAs in Macrophages

(2012) W. Zhao et al.   JOURNAL OF IMMUNOLOGY

The biochemistry of activation-induced deaminase and its physiological functions

(2012) Mani Larijani et al.   SEMINARS IN IMMUNOLOGY

Activation-induced cytidine deaminase structure and functions: A species comparative view

(2011) Vasco M. Barreto et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense

(2011) Min Wei et al.   NATURE IMMUNOLOGY

Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3′ UTRs

(2011) Brad R Rosenberg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation

(2011) I.-m. Okazaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determinants of sequence-specificity within human AID and APOBEC3G

(2010) Michael A. Carpenter et al.   DNA REPAIR

Atomic Force Microscopy Studies Provide Direct Evidence for Dimerization of the HIV Restriction Factor APOBEC3G

(2010) Luda S. Shlyakhtenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino-Terminal Phosphorylation of Activation-Induced Cytidine Deaminase Suppresses c-myc/IgH Translocation

(2010) A. Gazumyan et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination

(2010) A. Stanlie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active nuclear import and cytoplasmic retention of activation-induced deaminase

(2009) Anne-Marie Patenaude et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination

(2009) Tomomitsu Doi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA

(2009) Yeshitila N Friew et al.   Retrovirology

RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1

(2009) Hendrik Huthoff et al.   PLoS Pathogens

Bimolecular Fluorescence Complementation (BiFC) Analysis as a Probe of Protein Interactions in Living Cells

(2008) Tom K. Kerppola   Annual Review of Biophysics

Is AID a monomer in solution?

(2008) Ashok S. Bhagwat et al.   DNA REPAIR

The AID/APOBEC family of nucleic acid mutators

(2008) Silvestro G Conticello   GENOME BIOLOGY

Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA

(2007) Sukhdev S. Brar et al.   DNA REPAIR