The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions

Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination

(2013) Lela Lackey et al.   CELL CYCLE

Atomic force microscopy studies of APOBEC3G oligomerization and dynamics

(2013) Luda S. Shlyakhtenko et al.   JOURNAL OF STRUCTURAL BIOLOGY

Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity

(2013) Axel V. Horn et al.   NUCLEIC ACIDS RESEARCH

Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain

(2013) Markus-Frederik Bohn et al.   STRUCTURE

Creative deaminases, self-inflicted damage, and genome evolution

(2012) Silvestro G. Conticello   Annals of the New York Academy of Sciences

APOBEC2 Is a Monomer in Solution: Implications for APOBEC3G Models

(2012) Troy C. Krzysiak et al.   BIOCHEMISTRY

AID and Apobec3G haphazard deamination and mutational diversity

(2012) Malgorzata Jaszczur et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The APOBEC3C crystal structure and the interface for HIV-1 Vif binding

(2012) Shingo Kitamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

Random Mutagenesis MAPPIT Analysis Identifies Binding Sites for Vif and Gag in Both Cytidine Deaminase Domains of Apobec3G

(2012) Isabel Uyttendaele et al.   PLoS One

Direct evidence that RNA inhibits APOBEC3G ssDNA cytidine deaminase activity

(2011) William M. McDougall et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

(2011) Sébastien Landry et al.   EMBO REPORTS

Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis

(2011) Shunsuke Okuyama et al.   INTERNATIONAL JOURNAL OF CANCER

Deaminase Activity on Single-stranded DNA (ssDNA) Occursin Vitrowhen APOBEC3G Cytidine Deaminase Forms Homotetramers and Higher-order Complexes

(2011) William M. McDougall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intensity of Deoxycytidine Deamination of HIV-1 Proviral DNA by the Retroviral Restriction Factor APOBEC3G Is Mediated by the Noncatalytic Domain

(2011) Yuqing Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APOBEC1-Mediated Editing and Attenuation of Herpes Simplex Virus 1 DNA Indicate That Neurons Have an Antiviral Role during Herpes Simplex Encephalitis

(2011) P. Gee et al.   JOURNAL OF VIROLOGY

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1

(2011) J. F. Hultquist et al.   JOURNAL OF VIROLOGY

Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3′ UTRs

(2011) Brad R Rosenberg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons

(2011) Terumasa Ikeda et al.   NUCLEIC ACIDS RESEARCH

APOBEC3G: a double agent in defense

(2011) Harold C. Smith   TRENDS IN BIOCHEMICAL SCIENCES

Functional analysis of the two cytidine deaminase domains in APOBEC3G

(2011) Xiaoyu Li et al.   VIROLOGY

The mechanisms regulating the subcellular localization of AID

(2011) Anne-Marie Patenaude et al.   Nucleus

APOBEC2, a selective inhibitor of TGFβ signaling, regulates left–right axis specification during early embryogenesis

(2010) Alin Vonica et al.   DEVELOPMENTAL BIOLOGY

Cytidine deaminases: AIDing DNA demethylation?

(2010) E. L. Fritz et al.   GENES & DEVELOPMENT

Atomic Force Microscopy Studies Provide Direct Evidence for Dimerization of the HIV Restriction Factor APOBEC3G

(2010) Luda S. Shlyakhtenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Model for Deoxycytidine Deamination Mechanisms of the HIV-1 Inactivation Enzyme APOBEC3G

(2010) Linda Chelico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apobec-1 Complementation Factor Modulates Liver Regeneration by Post-transcriptional Regulation of Interleukin-6 mRNA Stability

(2010) Valerie Blanc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

Rationalisation of the Differences between APOBEC3G Structures from Crystallography and NMR Studies by Molecular Dynamics Simulations

(2010) Flavia Autore et al.   PLoS One

Diverse functions for DNA and RNA editing in the immune system

(2010) Claire E. Hamilton et al.   RNA Biology

Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces

(2010) Shivender M.D. Shandilya et al.   STRUCTURE

A Hydrodynamic Analysis of APOBEC3G Reveals a Monomer−Dimer−Tetramer Self-Association That Has Implications for Anti-HIV Function

(2009) Jason D. Salter et al.   BIOCHEMISTRY

Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G

(2009) Ayako Furukawa et al.   EMBO JOURNAL

Decreased Expression of Cholesterol 7α-Hydroxylase and Altered Bile Acid Metabolism inApobec-1−/−Mice Lead to Increased Gallstone Susceptibility

(2009) Yan Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Portable Hot Spot Recognition Loop Transfers Sequence Preferences from APOBEC Family Members to Activation-induced Cytidine Deaminase

(2009) Rahul M. Kohli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Extended Structure of the APOBEC3G Catalytic Domain Suggests a Unique Holoenzyme Model

(2009) Elena Harjes et al.   JOURNAL OF MOLECULAR BIOLOGY

Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis

(2009) Delphine Lavens et al.   NUCLEIC ACIDS RESEARCH

Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation

(2009) B. Stauch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human APOBEC1 cytidine deaminase edits HBV DNA

(2009) Minerva Gonzalez et al.   Retrovirology

Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA

(2009) Yeshitila N Friew et al.   Retrovirology

RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1

(2009) Hendrik Huthoff et al.   PLoS Pathogens

Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1

(2008) Lindi Tan et al.   FASEB JOURNAL

APOBEC3G Subunits Self-associate via the C-terminal Deaminase Domain

(2008) Ryan P. Bennett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Model for Oligomeric Regulation of APOBEC3G Cytosine Deaminase-dependent Restriction of HIV

(2008) Linda Chelico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasomal degradation restricts the nuclear lifespan of AID

(2008) Said Aoufouchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Two Regions within the Amino-Terminal Half of APOBEC3G Cooperate To Determine Cytoplasmic Localization

(2008) M. D. Stenglein et al.   JOURNAL OF VIROLOGY

Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

(2008) R. S. LaRue et al.   JOURNAL OF VIROLOGY

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

(2008) Lauren G. Holden et al.   NATURE

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

(2008) Kuan-Ming Chen et al.   NATURE

Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C

(2008) Tao Wang et al.   VIROLOGY

APOBEC3G Inhibits Elongation of HIV-1 Reverse Transcripts

(2008) Kate N. Bishop et al.   PLoS Pathogens

The AID/APOBEC family of nucleic acid mutators

(2008) Silvestro G Conticello   GENOME BIOLOGY

Interaction with 7SL RNA but Not with HIV-1 Genomic RNA or P Bodies Is Required for APOBEC3F Virion Packaging

(2007) Tao Wang et al.   JOURNAL OF MOLECULAR BIOLOGY