Synthetic gene network restoring endogenous pituitary–thyroid feedback control in experimental Graves’ disease

A Synthetic Erectile Optogenetic Stimulator Enabling Blue-Light-Inducible Penile Erection

(2015) Taeuk Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies

(2015) Terry F Davies et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling

(2015) Lars Grøntved et al.   Nature Communications

Defending plasma T3 is a biological priority

(2014) Sherine M. Abdalla et al.   CLINICAL ENDOCRINOLOGY

The Ability of Thyroid Hormone Receptors to Sense T4as an Agonist Depends on Receptor Isoform and on Cellular Cofactors

(2014) Amy Schroeder et al.   MOLECULAR ENDOCRINOLOGY

A general design strategy for protein-responsive riboswitches in mammalian cells

(2014) Simon Ausländer et al.   NATURE METHODS

Thyroid Hormone Regulation of Metabolism

(2014) Rashmi Mullur et al.   PHYSIOLOGICAL REVIEWS

Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant

(2014) Marc Folcher et al.   Nature Communications

A designer cell-based histamine-specific human allergy profiler

(2014) David Ausländer et al.   Nature Communications

Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient

(2013) D. Jacobs-Tulleneers-Thevissen et al.   DIABETOLOGIA

A Selective TSH Receptor Antagonist Inhibits Stimulation of Thyroid Function in Female Mice

(2013) Susanne Neumann et al.   ENDOCRINOLOGY

Diagnosis and management of Graves disease: a global overview

(2013) Luigi Bartalena   Nature Reviews Endocrinology

Transferring a synthetic gene circuit from yeast to mammalian cells

(2013) Dmitry Nevozhay et al.   Nature Communications

A closed-loop synthetic gene circuit for the treatment of diet-induced obesity in mice

(2013) Katrin Rössger et al.   Nature Communications

Mechanisms of thyroid hormone action

(2012) Gregory A. Brent   JOURNAL OF CLINICAL INVESTIGATION

Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome

(2012) H. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging pharmacotherapy for treatment of Graves’ disease

(2012) Rebecca S Bahn   Expert Review of Clinical Pharmacology

Radioiodine Therapy for Hyperthyroidism

(2011) Douglas S. Ross   NEW ENGLAND JOURNAL OF MEDICINE

When Will Thyrotropin Receptor Antagonists and Inverse Thyrotropin Receptor Agonists Become Available for Clinical Use?

(2011) Charles H. Emerson   THYROID

The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis

(2010) Christopher J. Potter et al.   CELL

Self-sufficient control of urate homeostasis in mice by a synthetic circuit

(2010) Christian Kemmer et al.   NATURE BIOTECHNOLOGY

Graves' Ophthalmopathy

(2010) Rebecca S. Bahn   NEW ENGLAND JOURNAL OF MEDICINE

Variable Suppression of Serum Thyroxine in Female Mice of Different Inbred Strains by Triiodothyronine Administered in Drinking Water

(2010) Sepehr Hamidi et al.   THYROID

The Superagonistic Activity of Bovine Thyroid-stimulating Hormone (TSH) and the Human TR1401 TSH Analog Is Determined by Specific Amino Acids in the Hinge Region of the Human TSH Receptor

(2009) Sandra Mueller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Graves' Disease

(2008) Gregory A. Brent   NEW ENGLAND JOURNAL OF MEDICINE