Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape

Non-genetic cancer cell plasticity and therapy-induced stemness in tumour relapse: ‘What does not kill me strengthens me’

(2015) A O Pisco et al.   BRITISH JOURNAL OF CANCER

Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential Mechanism

(2015) Peter Csermely et al.   SEMINARS IN CANCER BIOLOGY

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

(2014) Kotaro Ohnishi et al.   CELL

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

(2014) S. C. Mack et al.   NATURE

Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells

(2013) Sui Huang   CANCER AND METASTASIS REVIEWS

Non-Darwinian dynamics in therapy-induced cancer drug resistance

(2013) Angela Oliveira Pisco et al.   Nature Communications

Wnt-Notch signalling: An integrated mechanism regulating transitions between cell states

(2012) Silvia Muñoz-Descalzo et al.   BIOESSAYS

A Missing Link in Genotype-Directed Cancer Therapy

(2012) René Bernards   CELL

Predicting rates of cell state change caused by stochastic fluctuations using a data-driven landscape model

(2012) D. R. Sisan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In defense of the somatic mutation theory of cancer

(2011) David L. Vaux   BIOESSAYS

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways

(2011) S. Huang   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

On the intrinsic inevitability of cancer: From foetal to fatal attraction

(2011) Sui Huang   SEMINARS IN CANCER BIOLOGY

Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized

(2010) Elsa Quintana et al.   CANCER CELL

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Cancer stem cells versus phenotype-switching in melanoma

(2010) Keith S. Hoek et al.   Pigment Cell & Melanoma Research

Functional Heterogeneity of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript

(2010) Maurice A. Canham et al.   PLOS BIOLOGY

Evolutionary Theory of Cancer

(2009) Camille Stephan-Otto Attolini et al.   Annals of the New York Academy of Sciences

A network view of disease and compound screening

(2009) Eric E. Schadt et al.   NATURE REVIEWS DRUG DISCOVERY

Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

(2009) Tibor Kalmar et al.   PLOS BIOLOGY

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE