Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN

Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme

(2016) Vanja Stojković et al.   NUCLEIC ACIDS RESEARCH

Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA

(2016) E. L. Schwalm et al.   SCIENCE

Mechanistic Diversity of RadicalS-Adenosylmethionine (SAM)-dependent Methylation

(2014) Matthew R. Bauerle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a Cross-Linked Protein–Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmN

(2014) Alexey Silakov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr

(2013) Tyler L Grove et al.   Nature Chemical Biology

Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae

(2013) Sunny Sharma et al.   NUCLEIC ACIDS RESEARCH

RNA-methyltransferase TrmA is a dual-specific enzyme responsible forC5-methylation of uridine in both tmRNA and tRNA

(2013) Ehsan Ranaei-Siadat et al.   RNA Biology

Covalent Intermediate in the Catalytic Mechanism of the Radical S-Adenosyl-l-methionine Methyl Synthase RlmN Trapped by Mutagenesis

(2012) Kevin P. McCusker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

The last rRNA methyltransferase of E. coli revealed: The yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA

(2012) A. Y. Golovina et al.   RNA

The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy

(2012) A. Benitez-Paez et al.   RNA

Inactivation of the Indigenous Methyltransferase RlmN in Staphylococcus aureus Increases Linezolid Resistance

(2011) Jacqueline M. LaMarre et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cfr and RlmN Contain a Single [4Fe-4S] Cluster, which Directs Two Distinct Reactivities forS-Adenosylmethionine: Methyl Transfer by SN2 Displacement and Radical Generation

(2011) Tyler L. Grove et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center

(2011) Haripriya Ramu et al.   MOLECULAR CELL

RNA methylation by Radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift

(2011) F. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Radically Different Mechanism for S-Adenosylmethionine-Dependent Methyltransferases

(2011) T. L. Grove et al.   SCIENCE

Structural Basis for Methyl Transfer by a Radical SAM Enzyme

(2011) A. K. Boal et al.   SCIENCE

tRNA Stabilization by Modified Nucleotides

(2010) Yuri Motorin et al.   BIOCHEMISTRY

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

(2010) Nora Vázquez-Laslop et al.   EMBO JOURNAL

RlmN and Cfr are Radical SAM Enzymes Involved in Methylation of Ribosomal RNA

(2010) Feng Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNALeu isoacceptors

(2010) A. Benitez-Paez et al.   RNA

Two Novel Point Mutations in Clinical Staphylococcus aureus Reduce Linezolid Susceptibility and Switch on the Stringent Response to Promote Persistent Infection

(2010) Wei Gao et al.   PLoS Pathogens

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

YgdE is the 2′-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA

(2009) Elzbieta Purta et al.   MOLECULAR MICROBIOLOGY

5-methylcytosine in RNA: detection, enzymatic formation and biological functions

(2009) Yuri Motorin et al.   NUCLEIC ACIDS RESEARCH

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Vienna RNA Websuite

(2008) A. R. Gruber et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways. 2008 update

(2008) A. Czerwoniec et al.   NUCLEIC ACIDS RESEARCH

Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases

(2008) A. Alian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA