Mechanical Stretch Induces Apoptosis Regulator TRB3 in Cultured Cardiomyocytes and Volume-Overloaded Heart

New directions in ER stress-induced cell death

(2013) Susan E. Logue et al.   APOPTOSIS

Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes

(2013) Joo Hee Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A crosstalk between p21 and UPR-induced transcription factor C/EBP homologous protein (CHOP) linked to type 2 diabetes

(2013) Chrysovalantou Mihailidou et al.   BIOCHIMIE

Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction

(2013) Christian Hill et al.   CARDIOVASCULAR RESEARCH

Protection from renal fibrosis, putative role of TRIB3 gene silencing

(2013) Wen-yuan Ding et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2

(2013) Weixia Sun et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cyclical stretch induces structural changes in atrial myocytes

(2013) Anne Margreet De Jong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGF  pathways as fundamental Notch regulators in breast cancer

(2013) J. Izrailit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle

(2013) Ho-Jin Koh et al.   Nature Communications

SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway

(2012) Antonio Cittadini et al.   CARDIOVASCULAR RESEARCH

Berberine inhibits norepinephrine-induced apoptosis in neonatal rat cardiomyocytes via inhibiting ROS-TNF-α-caspase signaling pathway

(2012) Xiu-xiu Lv et al.   Chinese Journal of Integrative Medicine

Silence of TRIB3 Suppresses Atherosclerosis and Stabilizes Plaques in Diabetic ApoE-/-/LDL Receptor-/- Mice

(2012) Z.-h. Wang et al.   DIABETES

Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1

(2012) Siyu Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-α-induced apoptosis

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The Effect of Pressure-Induced Mechanical Stretch on Vascular Wall Differential Gene Expression

(2012) M.A. Anwar et al.   JOURNAL OF VASCULAR RESEARCH

Global analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death

(2011) Mark Kristiansen et al.   BMC GENOMICS

Emodin-induced microglial apoptosis is associated with TRB3 induction

(2011) Xueping Zhou et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Differential effects of the tumor necrosis factor alpha-blocker infliximab and etanercept on immunocompetent cells in vitro

(2011) Firas Thaher et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TRB3 interacts with SMAD3 promoting tumor cell migration and invasion

(2011) F. Hua et al.   JOURNAL OF CELL SCIENCE

Changes in cardiac structure in hypertension produced by placental ischemia in pregnant rats: effect of tumor necrosis factor blockade

(2011) Jolanta Gutkowska et al.   JOURNAL OF HYPERTENSION

TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma

(2011) Jing Zhang et al.   ORAL ONCOLOGY

Akt2: A Critical Regulator of Cardiomyocyte Survival and Metabolism

(2011) Anthony J. Muslin   PEDIATRIC CARDIOLOGY

UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression

(2010) Carla R. Bromati et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The TRIB3 R84 variant is associated with increased carotid intima–media thickness in vivo and with enhanced MAPK signalling in human endothelial cells

(2010) Gloria Formoso et al.   CARDIOVASCULAR RESEARCH

TRB3 Function in Cardiac Endoplasmic Reticulum Stress

(2010) Joan Avery et al.   CIRCULATION RESEARCH

The emerging role of TRIB3 as a gene affecting human insulin resistance and related clinical outcomes

(2009) Sabrina Prudente et al.   ACTA DIABETOLOGICA

Endoplasmic reticulum stress mediates γ-tocotrienol-induced apoptosis in mammary tumor cells

(2009) Vikram B. Wali et al.   APOPTOSIS

Pressure-Mediated Hypertrophy and Mechanical Stretch Induces IL-1 Release and Subsequent IGF-1 Generation to Maintain Compensative Hypertrophy by Affecting Akt and JNK Pathways

(2009) Shoken Honsho et al.   CIRCULATION RESEARCH

S100B Interaction With the Receptor for Advanced Glycation End Products (RAGE)

(2009) J.N. Tsoporis et al.   CIRCULATION RESEARCH

Cardioprotection by CaMKII-δB Is Mediated by Phosphorylation of Heat Shock Factor 1 and Subsequent Expression of Inducible Heat Shock Protein 70

(2009) Wei Peng et al.   CIRCULATION RESEARCH

Effects of Mechanical Stress and Carvedilol in Lamin A/C–Deficient Dilated Cardiomyopathy

(2009) Suchitra Chandar et al.   CIRCULATION RESEARCH

Regulation of GADD153 induced by mechanical stress in cardiomyocytes

(2009) W. P. Cheng et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Rapamycin reduces high-amplitude, mechanical stretch-induced apoptosis in pulmonary microvascular endothelial cells

(2009) Uwe Raaz et al.   MICROVASCULAR RESEARCH