The antigenotoxic potential of dietary flavonoids

Antigenotoxic and antioxidant activities of a polyphenolic extract from European Dracocephalum moldavica L.

(2016) Ana Clara Aprotosoaie et al.   INDUSTRIAL CROPS AND PRODUCTS

Quercetin: A flavonol with multifaceted therapeutic applications?

(2015) Gabriele D'Andrea   FITOTERAPIA

Catechins: Sources, extraction and encapsulation: A review

(2015) Pravin Vasantrao Gadkari et al.   FOOD AND BIOPRODUCTS PROCESSING

The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin

(2015) Merve Bacanlı et al.   FOOD AND CHEMICAL TOXICOLOGY

Genotoxicity evaluation of the flavonoid, myricitrin, and its aglycone, myricetin

(2015) Cheryl A. Hobbs et al.   FOOD AND CHEMICAL TOXICOLOGY

Pharmacological Profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)

(2015) Ming Liu et al.   MOLECULES

Evaluation of Antigenotoxic Effects of Plant Flavonoids Quercetin and Rutin on HepG2 Cells

(2015) Gustavo R. M. Barcelos et al.   PHYTOTHERAPY RESEARCH

Protective effect of (−)-epigallocatechin-3-gallate on capsaicin-induced DNA damage and oxidative stress in human erythrocyes and leucocytes in vitro

(2014) Dilek Pandır   CYTOTECHNOLOGY

Intake of anthocyanidins pelargonidin and cyanidin reduces genotoxic stress in mice induced by diepoxybutane, urethane and endogenous nitrosation

(2014) Nidhi Khandelwal et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Differential effect of manool – A diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells

(2014) Heloiza Diniz Nicolella et al.   FOOD AND CHEMICAL TOXICOLOGY

Genotoxic and cytotoxic effects of doxorubicin and silymarin on human hepatocellular carcinoma cells

(2014) E Yurtcu et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Genotoxic Anti-Cancer Agents and Their Relationship to DNA Damage, Mitosis, and Checkpoint Adaptation in Proliferating Cancer Cells

(2014) Lucy Swift et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antigenotoxic Effects of (–)-Epigallocatechin-3-Gallate (EGCG), Quercetin, and Rutin on Chromium Trioxide-Induced Micronuclei in the Polychromatic Erythrocytes of Mouse Peripheral Blood

(2014) María del Carmen García-Rodríguez et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Protective effect of apigenin against N-nitrosodiethylamine (NDEA)-induced hepatotoxicity in albino rats

(2014) Fahad Ali et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Antihypertensive effects of the flavonoid quercetin

(2014) Francisco Perez-Vizcaino et al.   Pharmacological Reports

Antigenotoxic effect of genistein against 7,12-dimethylbenz[a]anthracene induced genotoxicity in bone marrow cells of female wistar rats

(2014) Pachaiappan Pugalendhi et al.   Pharmacological Reports

Anti-proliferative effects of quercetin and catechin metabolites

(2014) Laura Delgado et al.   Food & Function

Antigenotoxic potential of rutin and quercetin in Swiss mice exposed to gamma radiation

(2014) ShrikantL Patil et al.   Biomedical Journal

Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells — up regulation of Nrf2 expression and down regulation of NF-κB and COX-2

(2013) Periasamy Ramyaa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cyanidin reverses cisplatin-induced apoptosis in HK-2 proximal tubular cells through inhibition of ROS-mediated DNA damage and modulation of the ERK and AKT pathways

(2013) Si Gao et al.   CANCER LETTERS

DNA repair mechanisms in dividing and non-dividing cells

(2013) Teruaki Iyama et al.   DNA REPAIR

Effect of blueberry pretreatment on diethylnitrosamine-induced oxidative stress and liver injury in rats

(2013) İlknur Bingül et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Ochratoxin-induced toxicity, oxidative stress and apoptosis ameliorated by quercetin – Modulation by Nrf2

(2013) Periasamy Ramyaa et al.   FOOD AND CHEMICAL TOXICOLOGY

Determination of the antigenotoxic potencies of some luteolin derivatives by using a eukaryotic cell system, Saccharomyces cerevisiae

(2013) Furkan Orhan et al.   FOOD CHEMISTRY

Cytochrome P450 isoforms are differently up-regulated in aflatoxin B1-exposed human lymphocytes and monocytes

(2013) Abbas Bahari et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

A review on plant-based rutin extraction methods and its pharmacological activities

(2013) Lee Suan Chua   JOURNAL OF ETHNOPHARMACOLOGY

Genotoxic and cytotoxic effects of testosterone cypionate (deposteron®)

(2013) José Roberto C. Meireles et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO

(2013) Yuhan Tang et al.   PHYTOMEDICINE

Effects of quercetin on LPS-induced disseminated intravascular coagulation (DIC) in rabbits

(2013) Pan-xi Yu et al.   THROMBOSIS RESEARCH

Anthocyanins suppress the cleavable complex formation by irinotecan and diminish its DNA-strand-breaking activity in the colon of Wistar rats

(2012) M. Esselen et al.   CARCINOGENESIS

Chemoprotective activity of the isoflavones, genistein and daidzein on mutagenicity induced by direct and indirect mutagens in cultured HTC cells

(2012) Sandra Regina Lepri et al.   CYTOTECHNOLOGY

The influence of curcumin and (–)-epicatechin on the genotoxicity and myelosuppression induced by etoposide in bone marrow cells of male rats

(2012) Monika A. Papież   DRUG AND CHEMICAL TOXICOLOGY

Review of current and “omics” methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms

(2012) Moustapha Ouedraogo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Quercetin Treatment Ameliorates Inflammation and Fibrosis in Mice with Nonalcoholic Steatohepatitis1–3

(2012) Eder Marcolin et al.   JOURNAL OF NUTRITION

Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo

(2012) Yu-Ting Cheng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Radio-modulatory effects of Green Tea Catechin EGCG on pBR322 plasmid DNA and murine splenocytes against gamma-radiation induced damage

(2012) Benila Richi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Analysis of in vitro chemoprevention of genotoxic damage by phytochemicals, as single agents or as combinations

(2012) Suresh K. Abraham et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Effects of quercetin on the bioavailability of doxorubicin in rats: Role of CYP3A4 and P-gp inhibition by quercetin

(2011) Jun-Shik Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models

(2011) Robert Kleemann et al.   ATHEROSCLEROSIS

An Update on Direct Genotoxicity as a Molecular Mechanism of Ochratoxin A Carcinogenicity

(2011) Annie Pfohl-Leszkowicz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38

(2011) Ana Belén Granado-Serrano et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Evaluating the radioprotective effect of hesperidin in the liver of Swiss albino mice

(2011) Kalyanasundaram Banumathy Kalpana et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

DNA-protective effects of quercetin or naringenin in alloxan-induced diabetic mice

(2011) Nada Oršolić et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Influence of resveratrol on oxidative damage in genomic DNA and apoptosis induced by cisplatin

(2011) Sabry M. Attia   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The human health effects of ozone depletion and interactions with climate change

(2011) M. Norval et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Influence of naringin on cadmium-induced genomic damage in human lymphocytes in vitro

(2011) Dilek Yılmaz et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Antiproliferative mechanisms of quercetin in rat activated hepatic stellate cells

(2011) Li-chen Wu et al.   Food & Function

Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells

(2010) Juliana Cristina Marcarini et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Anticlastogenic effect of apigenin in human lymphocytes treated with ethinylestradiol

(2010) Yasir Hasan Siddique et al.   FITOTERAPIA

Hesperetin protects testicular toxicity of doxorubicin in rat: Role of NFκB, p38 and caspase-3

(2010) P.P. Trivedi et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of (+)catechin and (−)epicatechin on heterocyclic amines-induced oxidative DNA damage

(2010) Ana Isabel Haza et al.   JOURNAL OF APPLIED TOXICOLOGY

Protective effects of Ursolic acid and Luteolin against oxidative DNA damage include enhancement of DNA repair in Caco-2 cells

(2010) Alice A. Ramos et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Oxidative stress in prostate cancer

(2009) Lakshmipathi Khandrika et al.   CANCER LETTERS

Antigenotoxic Effect of Genistein and Gingerol on Genotoxicity Induced by Norethandrolone and Oxandrolone in Cultured Human Lymphocytes

(2009) Mohammad Afzal et al.   International Journal of Pharmacology

Distribution and Biological Activities of the Flavonoid Luteolin

(2009) Miguel Lopez-Lazaro   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Investigation of the radioprotective efficacy of hesperidin against gamma-radiation induced cellular damage in cultured human peripheral blood lymphocytes

(2009) K.B. Kalpana et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Protective effects of hesperidin against genotoxicity induced by 99mTc-MIBI in human cultured lymphocyte cells

(2009) Seyed Jalal Hosseinimehr et al.   NUCLEAR MEDICINE AND BIOLOGY

Antioxidant and antimutagenic effect of quercetin against DEN induced hepatotoxicity in rat

(2009) C. Gupta et al.   PHYTOTHERAPY RESEARCH

Myricetin, quercetin, (+)-catechin and (−)-epicatechin protect against N-nitrosamines-induced DNA damage in human hepatoma cells

(2009) M.E. Delgado et al.   TOXICOLOGY IN VITRO

Dietary polyphenols protect against N-nitrosamines and benzo(a)pyrene-induced DNA damage (strand breaks and oxidized purines/pyrimidines) in HepG2 human hepatoma cells

(2008) Maria Eugenia Delgado et al.   EUROPEAN JOURNAL OF NUTRITION

Health effects of quercetin: From antioxidant to nutraceutical

(2008) Agnes W. Boots et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antigenotoxic effect of apigenin against mitomycin C induced genotoxic damage in mice bone marrow cells

(2008) Yasir Hasan Siddique et al.   FOOD AND CHEMICAL TOXICOLOGY

Metabolism and toxicology of heterocyclic aromatic amines when consumed in diet: Influence of the genetic susceptibility to develop human cancer. A review

(2008) Maite Sanz Alaejos et al.   FOOD RESEARCH INTERNATIONAL

Catechin, epicatechin, quercetin, rutin and resveratrol in red grape: Content, in vitro antioxidant activity and interactions

(2008) P. Iacopini et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Antigenotoxic effects of quercetin, rutin and ursolic acid on HepG2 cells: Evaluation by the comet assay

(2008) A.A. Ramos et al.   TOXICOLOGY LETTERS

Antioxidant and antigenotoxic activities of Korean fermented soybean

(2007) Nam Yee Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Phenolic acids and flavonoids of fig fruit (Ficus carica L.) in the northern Mediterranean region

(2007) Robert Veberic et al.   FOOD CHEMISTRY

Protective effect of quercetin on nicotine-induced prooxidant and antioxidant imbalance and DNA damage in Wistar rats

(2007) Shanmugavelu Muthukumaran et al.   TOXICOLOGY

Antigenotoxic effect of Xanthohumol in rat liver slices

(2007) Janja Plazar et al.   TOXICOLOGY IN VITRO

Antigenotoxic effect of apigenin against anti-cancerous drugs

(2007) Yasir Hasan Siddique et al.   TOXICOLOGY IN VITRO