Rebuilding the Damaged Heart: Mesenchymal Stem Cells, Cell-Based Therapy, and Engineered Heart Tissue
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Title
Rebuilding the Damaged Heart: Mesenchymal Stem Cells, Cell-Based Therapy, and Engineered Heart Tissue
Authors
Keywords
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Journal
PHYSIOLOGICAL REVIEWS
Volume 96, Issue 3, Pages 1127-1168
Publisher
American Physiological Society
Online
2016-06-23
DOI
10.1152/physrev.00019.2015
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- Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes
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- SDF-1α as a therapeutic stem cell homing factor in myocardial infarction
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- TNF RECEPTOR 2, NOT TNF RECEPTOR 1, ENHANCES MESENCHYMAL STEM CELL-MEDIATED CARDIAC PROTECTION FOLLOWING ACUTE ISCHEMIA
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- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
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- Transforming Growth Factor-β and Notch Signaling Mediate Stem Cell Differentiation into Smooth Muscle Cells
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- Effect of 5-Azacytidine: Evidence for Alteration of the Multipotent Ability of Mesenchymal Stem Cells
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- Mesenchymal stem cells attenuate myocardial functional depression and reduce systemic and myocardial inflammation during endotoxemia
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- HO-1 modified mesenchymal stem cells modulate MMPs/TIMPs system and adverse remodeling in infarcted myocardium
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- Improved Function and Myocardial Repair of Infarcted Heart by Intracoronary Injection of Mesenchymal Stem Cell-Derived Growth Factors
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- Role of matrix metalloproteinases in skeletal muscle
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- Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen
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- Combining neuropeptide Y and mesenchymal stem cells reverses remodeling after myocardial infarction
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- Allogeneic Mesenchymal Precursor Cell Therapy to Limit Remodeling After Myocardial Infarction: The Effect of Cell Dosage
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- Combined transplantation of endothelial progenitor cells and mesenchymal stem cells into a rat model of isoproterenol-induced myocardial injury
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- Combined Therapy With Simvastatin and Bone Marrow–Derived Mesenchymal Stem Cells Increases Benefits in Infarcted Swine Hearts
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- Amplification of Coronary Arteriogenic Capacity of Multipotent Stromal Cells by Epidermal Growth Factor
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- Chemical and physical stimuli induce cardiomyocyte differentiation from stem cells
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- Direct injection of autologous mesenchymal stromal cells improves myocardial function
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- Paracrine Role for Mesenchymal Stem Cells in Acute Myocardial Infarction
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- Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation
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- Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury
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- Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis
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- Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix
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- Hepatocyte growth factor-mediated attraction of mesenchymal stem cells for apoptotic neuronal and cardiomyocytic cells
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- Cell Sheet-Based Myocardial Tissue Engineering: New Hope for Damaged Heart Rescue
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- Human bone marrow stem cells co-cultured with neonatal rat cardiomyocytes display limited cardiomyogenic plasticity
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- Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathy
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- Transplantation with survivin-engineered mesenchymal stem cells results in better prognosis in a rat model of myocardial infarction
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- Dissecting coronary angiogenesis: 3D co-culture of cardiomyocytes with endothelial or mesenchymal cells
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- Endothelial differentiation of Wharton's jelly–derived mesenchymal stem cells in comparison with bone marrow–derived mesenchymal stem cells
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- Cardiac pre-differentiation of human mesenchymal stem cells by electrostimulation
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- Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells
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- Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats
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- Bone marrow mesenchymal stem cells upregulate transient outward potassium currents in postnatal rat ventricular myocytes
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- Pharmacological Preconditioning of Mesenchymal Stem Cells with Trimetazidine (1-[2,3,4-Trimethoxybenzyl]piperazine) Protects Hypoxic Cells against Oxidative Stress and Enhances Recovery of Myocardial Function in Infarcted Heart through Bcl-2 Expression
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- A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction
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- Mesenchymal stem cells modified with stromal cell-derived factor 1α improve cardiac remodeling via paracrine activation of hepatocyte growth factor in a rat model of myocardial infarction
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- Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles
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- Functional Profiling Reveals Critical Role for miRNA in Differentiation of Human Mesenchymal Stem Cells
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- Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity
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- Bone marrow Derived Pluripotent Cells are Pericytes which Contribute to Vascularization
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- Mesenchymal Stem Cells Promote Matrix Metalloproteinase Secretion by Cardiac Fibroblasts and Reduce Cardiac Ventricular Fibrosis After Myocardial Infarction
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- Bone Marrow–Derived Mesenchymal Stem Cells Promote Angiogenic Processes in a Time- and Dose-Dependent Manner In Vitro
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- Mesenchymal Stem Cells Require a Sufficient, Ongoing Immune Response to Exert Their Immunosuppressive Function
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- VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function
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- Early improvement in cardiac tissue perfusion due to mesenchymal stem cells
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- Donor-Derived Mesenchymal Stem Cells Remain Present and Functional in the Transplanted Human Heart
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- Intravenous infusion of mesenchymal stem cells enhances regional perfusion and improves ventricular function in a porcine model of myocardial infarction
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- VEGF improves survival of mesenchymal stem cells in infarcted hearts
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- Paracrine action of HO-1-modified mesenchymal stem cells mediates cardiac protection and functional improvement
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- Cardiac mesoangioblasts are committed, self-renewable progenitors, associated with small vessels of juvenile mouse ventricle
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- Stem Cell Regulation via Dynamic Interactions of the Nervous and Immune Systems with the Microenvironment
- (2008) Asaf Spiegel et al. Cell Stem Cell
- Ontogeny and Multipotency of Neural Crest-Derived Stem Cells in Mouse Bone Marrow, Dorsal Root Ganglia, and Whisker Pad
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- All MSCs Are Pericytes?
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- Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions
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- A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs
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- Comparison of Different Adult Stem Cell Types for Treatment of Myocardial Ischemia
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- Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy
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- Immuno-inflammatory regulation effect of mesenchymal stem cell transplantation in a rat model of myocardial infarction
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- Macrophage roles following myocardial infarction
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- Cell-to-cell cross-talk between mesenchymal stem cells and cardiomyocytes in co-culture
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- Histopathological Study of Healing After Allogenic Mesenchymal Stem Cell Delivery in Myocardial Infarction in Dogs
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- Pre-Treatment of Mesenchymal Stem Cells With a Combination of Growth Factors Enhances Gap Junction Formation, Cytoprotective Effect on Cardiomyocytes, and Therapeutic Efficacy for Myocardial Infarction
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- Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis
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- Reverse remodeling is associated with changes in extracellular matrix proteases and tissue inhibitors after mesenchymal stem cell (MSC) treatment of pressure overload hypertrophy
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- Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
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- Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart
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- TNFR gene-modified mesenchymal stem cells attenuate inflammation and cardiac dysfunction following MI
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- Nitric Oxide SUPPRESSES THE SECRETION OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND HEPATOCYTE GROWTH FACTOR FROM HUMAN MESENCHYMAL STEM CELLS
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- Secreted Frizzled-Related Protein-1 Enhances Mesenchymal Stem Cell Function in Angiogenesis and Contributes to Neovessel Maturation
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- Immunogenicity of Human Mesenchymal Stem Cells in HLA-Class I-Restricted T-Cell Responses Against Viral or Tumor-Associated Antigens
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- IFATS Collection: Adipose Stromal Cells Adopt a Proangiogenic Phenotype Under the Influence of Hypoxia
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- Identification and Purification of Mesodermal Progenitor Cells From Human Adult Bone Marrow
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- Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction
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- Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling
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- Toll-Like Receptors on Human Mesenchymal Stem Cells Drive Their Migration and Immunomodulating Responses
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- Bone Marrow-Derived Mesenchymal Stem Cells Induce Both Polyclonal Expansion and Differentiation of B Cells Isolated from Healthy Donors and Systemic Lupus Erythematosus Patients
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- Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells
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- Human Mesenchymal Stem Cells Inhibit Neutrophil Apoptosis: A Model for Neutrophil Preservation in the Bone Marrow Niche
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