ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

A Proliferative Burst during Preadolescence Establishes the Final Cardiomyocyte Number

(2014) Nawazish Naqvi et al.   CELL

High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation

(2014) D. W. Staudt et al.   DEVELOPMENT

Macrophages are required for neonatal heart regeneration

(2014) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

An emerging consensus on cardiac regeneration

(2014) Jop H van Berlo et al.   NATURE MEDICINE

Surgical models for cardiac regeneration in neonatal mice

(2014) Ahmed I Mahmoud et al.   Nature Protocols

Recombinant Neuregulin 1 Does Not Activate Cardiomyocyte DNA Synthesis in Normal or Infarcted Adult Mice

(2014) Sean Reuter et al.   PLoS One

 -Catenin Signaling Is a Critical Event in ErbB2-Mediated Mammary Tumor Progression

(2013) B. Schade et al.   CANCER RESEARCH

Cardiac Stem Cell Therapy and the Promise of Heart Regeneration

(2013) Jessica C. Garbern et al.   Cell Stem Cell

Identification of Chemicals Inducing Cardiomyocyte Proliferation in Developmental Stage–Specific Manner With Pluripotent Stem Cells

(2013) Hideki Uosaki et al.   Circulation-Cardiovascular Genetics

Hippo signaling impedes adult heart regeneration

(2013) T. Heallen et al.   DEVELOPMENT

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

(2013) Ahmed I. Mahmoud et al.   NATURE

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

(2013) Mei Xin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation

(2012) Brian Wadugu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Neuregulin in Cardiovascular Development and Disease

(2012) Oghenerukevwe Odiete et al.   CIRCULATION RESEARCH

Mammalian heart renewal by pre-existing cardiomyocytes

(2012) Samuel E. Senyo et al.   NATURE

Cardiac-Specific Over-Expression of Epidermal Growth Factor Receptor 2 (ErbB2) Induces Pro-Survival Pathways and Hypertrophic Cardiomyopathy in Mice

(2012) Polina Sysa-Shah et al.   PLoS One

Oncostatin M Is a Major Mediator of Cardiomyocyte Dedifferentiation and Remodeling

(2011) Thomas Kubin et al.   Cell Stem Cell

Cardiac muscle regeneration: lessons from development

(2011) M. Mercola et al.   GENES & DEVELOPMENT

Neuregulin-1β for the treatment of systolic heart failure

(2011) Douglas B. Sawyer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions

(2011) C-R Pradeep et al.   ONCOGENE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance

(2010) Russell S. Whelan et al.   Annual Review of Physiology

Neuregulin 1 Sustains the Gene Regulatory Network in Both Trabecular and Nontrabecular Myocardium

(2010) Donna Lai et al.   CIRCULATION RESEARCH

A dual role for ErbB2 signaling in cardiac trabeculation

(2010) J. Liu et al.   DEVELOPMENT

Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses

(2010) Andrew Jabbour et al.   EUROPEAN JOURNAL OF HEART FAILURE

A Phase II, Randomized, Double-Blind, Multicenter, Based on Standard Therapy, Placebo-Controlled Study of the Efficacy and Safety of Recombinant Human Neuregulin-1 in Patients With Chronic Heart Failure

(2010) Runlin Gao et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells

(2010) K. Zaoui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

(2009) Kevin Bersell et al.   CELL

From fish to amphibians to mammals: in search of novel strategies to optimize cardiac regeneration

(2009) Simonetta Ausoni et al.   JOURNAL OF CELL BIOLOGY

Nongenetic method for purifying stem cell–derived cardiomyocytes

(2009) Fumiyuki Hattori et al.   NATURE METHODS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Oncogene-Mediated Inhibition of Glycogen Synthase Kinase 3  Impairs Degradation of Prolactin Receptor

(2008) A. Plotnikov et al.   CANCER RESEARCH

The role of Neuregulin-1β/ErbB signaling in the heart

(2008) Laura Pentassuglia et al.   EXPERIMENTAL CELL RESEARCH